Baicalin_SNU-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Baicalin perturbation in SNU-1 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Baicalin_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
PCBP2 poly(rC) binding protein 2 0.0475065
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0436446
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.032341
EEF2 eukaryotic translation elongation factor 2 0.0313369
KMT2E lysine (K)-specific methyltransferase 2E 0.0308862
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0298857
EZR ezrin 0.0297623
FAM13A family with sequence similarity 13, member A 0.0275384
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0273391
SSBP2 single-stranded DNA binding protein 2 0.026846
FAT1 FAT atypical cadherin 1 0.0245974
HELZ helicase with zinc finger 0.0241233
CAMTA1 calmodulin binding transcription activator 1 0.024088
APLP2 amyloid beta (A4) precursor-like protein 2 0.02365
RCOR1 REST corepressor 1 0.0235337
ZNF608 zinc finger protein 608 0.0234976
ENO2 enolase 2 (gamma, neuronal) 0.02344
CCNL1 cyclin L1 0.0230295
ZNF292 zinc finger protein 292 0.0227777
RYBP RING1 and YY1 binding protein 0.022292
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0222515
FN1 fibronectin 1 0.0221914
NAMPT nicotinamide phosphoribosyltransferase 0.0217416
QKI QKI, KH domain containing, RNA binding 0.0212441
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.0208397
RPL3 ribosomal protein L3 0.0206809
KDM6A lysine (K)-specific demethylase 6A 0.0205422
HILPDA hypoxia inducible lipid droplet-associated 0.0202008
XPO1 exportin 1 0.0201194
RAB18 RAB18, member RAS oncogene family 0.0198756
UBA6 ubiquitin-like modifier activating enzyme 6 0.0198692
PER1 period circadian clock 1 0.0195039
ZNF451 zinc finger protein 451 0.0194823
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0187521
HDGF hepatoma-derived growth factor 0.0187302
FLNA filamin A, alpha 0.0184009
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 0.0178957
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 0.0174801
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.0174058
TSC22D2 TSC22 domain family, member 2 0.0171335
PCM1 pericentriolar material 1 0.0170903
SOX6 SRY (sex determining region Y)-box 6 0.0166844
ATOSA atos homolog A 0.016485
LMCD1 LIM and cysteine-rich domains 1 0.0164255
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 0.0163379
NDRG1 N-myc downstream regulated 1 0.0163313
POTEF POTE ankyrin domain family, member F 0.0163285
NUP58 nucleoporin 58 0.0162112
ADAM17 ADAM metallopeptidase domain 17 0.0159851
IGFBP3 insulin-like growth factor binding protein 3 0.0157012
VEGFA vascular endothelial growth factor A 0.0155738
SEPTIN7 septin 7 0.0155644
RNASE3 ribonuclease, RNase A family, 3 0.0155331
INSIG2 insulin induced gene 2 0.0151626
TENT4A terminal nucleotidyltransferase 4A 0.0151247
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 0.0147834
CNOT4 CCR4-NOT transcription complex, subunit 4 0.0147817
USP3 ubiquitin specific peptidase 3 0.0147391
TFG TRK-fused gene 0.0145386
COPA coatomer protein complex, subunit alpha 0.0145367
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 0.0144693
ZMIZ1 zinc finger, MIZ-type containing 1 0.0143311
ECT2 epithelial cell transforming 2 0.0142624
ARRDC3 arrestin domain containing 3 0.0141102
HMGA1 high mobility group AT-hook 1 0.0140977
ARHGAP12 Rho GTPase activating protein 12 0.0140024
SRP54 signal recognition particle 54kDa 0.0138612
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0.0138025
ANKRD36B ankyrin repeat domain 36B 0.0137075
TAC4 tachykinin 4 (hemokinin) 0.0136563
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 0.0134297
ZNF462 zinc finger protein 462 0.0132663
FGD4 FYVE, RhoGEF and PH domain containing 4 0.0132285
CABIN1 calcineurin binding protein 1 0.0131766
YAP1 Yes-associated protein 1 0.0130609
NCOR2 nuclear receptor corepressor 2 0.0130231
RPSA ribosomal protein SA 0.0129804
KIF5C kinesin family member 5C 0.0129427
CNOT6L CCR4-NOT transcription complex, subunit 6-like 0.0127177
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.0125933
CORO1C coronin, actin binding protein, 1C 0.0124958
SLMAP sarcolemma associated protein 0.012478
GATA6 GATA binding protein 6 0.0122388
TMF1 TATA element modulatory factor 1 0.0121167
RNMT RNA (guanine-7-) methyltransferase 0.012005
MED4 mediator complex subunit 4 0.0119783
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 0.0119553
RIOK3 RIO kinase 3 0.0119306
ZSWIM6 zinc finger, SWIM-type containing 6 0.0119275
TRA2B transformer 2 beta homolog (Drosophila) 0.0119237
CDK5RAP2 CDK5 regulatory subunit associated protein 2 0.0119212
BRD2 bromodomain containing 2 0.0118782
TENT2 terminal nucleotidyltransferase 2 0.011748
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.0116666
HYOU1 hypoxia up-regulated 1 0.0115537
OGA O-GlcNAcase 0.0115412
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 0.0112584
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.011194
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.0111797
EXOC5 exocyst complex component 5 0.0111736

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.221701
PTMA prothymosin, alpha -0.165668
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 -0.127552
PDE4D phosphodiesterase 4D, cAMP-specific -0.125676
VCL vinculin -0.117891
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.116348
AHNAK AHNAK nucleoprotein -0.11573
TPT1 tumor protein, translationally-controlled 1 -0.099323
NBEA neurobeachin -0.0976587
TMSB4X thymosin beta 4, X-linked -0.0935604
FOXP1 forkhead box P1 -0.0896339
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0870957
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0864432
EGFR epidermal growth factor receptor -0.0854657
ACTG1 actin gamma 1 -0.0842447
TXNRD1 thioredoxin reductase 1 -0.0800336
ADAM10 ADAM metallopeptidase domain 10 -0.076313
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0756607
S100A6 S100 calcium binding protein A6 -0.07229
ENOX1 ecto-NOX disulfide-thiol exchanger 1 -0.0719334
CPED1 cadherin-like and PC-esterase domain containing 1 -0.0694331
PKM pyruvate kinase, muscle -0.0690163
STAT1 signal transducer and activator of transcription 1, 91kDa -0.0652644
PYGB phosphorylase, glycogen; brain -0.0647417
CACNB4 calcium channel, voltage-dependent, beta 4 subunit -0.0600676
RPS6 ribosomal protein S6 -0.0593482
SMYD3 SET and MYND domain containing 3 -0.057655
MINDY2 MINDY lysine 48 deubiquitinase 2 -0.0566275
RPL12 ribosomal protein L12 -0.0557835
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0552714
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.0525442
LPP LIM domain containing preferred translocation partner in lipoma -0.0504639
LOC112694756 uncharaterized LOC112694756 -0.0477618
OSMR oncostatin M receptor -0.0477365
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b -0.046789
CCND1 cyclin D1 -0.04621
EIF1 eukaryotic translation initiation factor 1 -0.0453018
PDE4B phosphodiesterase 4B, cAMP-specific -0.0437191
ZBTB20 zinc finger and BTB domain containing 20 -0.0437158
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0430008
ARL4C ADP-ribosylation factor-like 4C -0.0425091
DOCK3 dedicator of cytokinesis 3 -0.0424573
EFNA5 ephrin-A5 -0.0423077
LDHA lactate dehydrogenase A -0.0421038
RPL35A ribosomal protein L35a -0.0408918
RPLP2 ribosomal protein, large, P2 -0.0405433
RPS19 ribosomal protein S19 -0.0398543
NF1 neurofibromin 1 -0.0392314
TM4SF1 transmembrane 4 L six family member 1 -0.0389933
ZMYND8 zinc finger, MYND-type containing 8 -0.0388879
RPL34 ribosomal protein L34 -0.0388875
TTC28 tetratricopeptide repeat domain 28 -0.0385978
RPS13 ribosomal protein S13 -0.0385909
HDLBP high density lipoprotein binding protein -0.0383289
RPL19 ribosomal protein L19 -0.038241
RPS8 ribosomal protein S8 -0.0376339
RPLP1 ribosomal protein, large, P1 -0.0374599
RPLP0 ribosomal protein, large, P0 -0.0373798
RPS24 ribosomal protein S24 -0.0373295
SLC38A2 solute carrier family 38, member 2 -0.0371931
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0367703
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 -0.0363741
PHF14 PHD finger protein 14 -0.0361388
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0357292
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.0356735
RPL26 ribosomal protein L26 -0.0356443
RPS23 ribosomal protein S23 -0.035512
FLNB filamin B, beta -0.0351878
PTPRG protein tyrosine phosphatase, receptor type, G -0.0351836
RPS25 ribosomal protein S25 -0.0347854
ANK2 ankyrin 2, neuronal -0.0342154
TAS2R14 taste receptor, type 2, member 14 -0.0340436
KLF3 Kruppel-like factor 3 (basic) -0.0340145
CLIP1 CAP-GLY domain containing linker protein 1 -0.0338212
RPL7A ribosomal protein L7a -0.0338084
NAP1L1 nucleosome assembly protein 1-like 1 -0.0334551
NFE2L2 nuclear factor, erythroid 2-like 2 -0.0332728
RPL11 ribosomal protein L11 -0.0331522
EXOC6B exocyst complex component 6B -0.0331387
CMSS1 cms1 ribosomal small subunit homolog (yeast) -0.0330854
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 -0.0327053
TCF12 transcription factor 12 -0.0321129
BMP10 bone morphogenetic protein 10 -0.0321027
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.0318882
RPL31 ribosomal protein L31 -0.0318313
NT5C2 5'-nucleotidase, cytosolic II -0.0312746
S100A4 S100 calcium binding protein A4 -0.0311483
RPS27A ribosomal protein S27a -0.0308994
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) -0.0308401
RPL4 ribosomal protein L4 -0.0306888
RSL1D1 ribosomal L1 domain containing 1 -0.0305594
HNRNPK heterogeneous nuclear ribonucleoprotein K -0.0304895
GNAS GNAS complex locus -0.0304404
KPNB1 karyopherin (importin) beta 1 -0.0304034
GLI2 GLI family zinc finger 2 -0.0297332
NCEH1 neutral cholesterol ester hydrolase 1 -0.0297099
DIAPH2 diaphanous-related formin 2 -0.029598
SPIDR scaffolding protein involved in DNA repair -0.02958
RTN4 reticulon 4 -0.029299
TBC1D5 TBC1 domain family, member 5 -0.0292564