| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Baicalin perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Baicalin_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0606327 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0568695 |
| SMAD3 | SMAD family member 3 | 0.0545643 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0513128 |
| PCBP2 | poly(rC) binding protein 2 | 0.0484723 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0480456 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.044762 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0436823 |
| TXNRD1 | thioredoxin reductase 1 | 0.0418709 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0413248 |
| TPX2 | TPX2, microtubule-associated | 0.0393884 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0390394 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.038697 |
| CENPF | centromere protein F, 350/400kDa | 0.0376012 |
| NAV2 | neuron navigator 2 | 0.0371284 |
| ZNF292 | zinc finger protein 292 | 0.036878 |
| YAP1 | Yes-associated protein 1 | 0.0367017 |
| DIAPH3 | diaphanous-related formin 3 | 0.0364008 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0353958 |
| KIAA1958 | KIAA1958 | 0.0350363 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0341401 |
| KIAA1328 | KIAA1328 | 0.0327351 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0321614 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0308243 |
| ECT2 | epithelial cell transforming 2 | 0.0307054 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.030681 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0305068 |
| CD44 | CD44 molecule (Indian blood group) | 0.0303532 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0302535 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0300261 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.029449 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0293453 |
| MKI67 | marker of proliferation Ki-67 | 0.0292837 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0292536 |
| SPAG9 | sperm associated antigen 9 | 0.0286556 |
| HJURP | Holliday junction recognition protein | 0.0285883 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0280595 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0279664 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0277319 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0276001 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0272913 |
| CEP250 | centrosomal protein 250kDa | 0.0272151 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0269426 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | 0.0264174 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0264162 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0259964 |
| XPO1 | exportin 1 | 0.0254325 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.025158 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0251524 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0251089 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0248843 |
| SGO2 | shugoshin 2 | 0.0243911 |
| ANLN | anillin, actin binding protein | 0.0243327 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.023727 |
| PER1 | period circadian clock 1 | 0.0235266 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0234746 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.0233668 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 | 0.0232669 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0231365 |
| MATR3 | matrin 3 | 0.0229445 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0226633 |
| RNF145 | ring finger protein 145 | 0.0225116 |
| PCNX1 | pecanex 1 | 0.0224889 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0224469 |
| TFG | TRK-fused gene | 0.022191 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0220881 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0219773 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0219566 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0219279 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.0218177 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0217527 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0217512 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0217443 |
| YBX3 | Y box binding protein 3 | 0.0216514 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0214923 |
| PCM1 | pericentriolar material 1 | 0.02141 |
| STK24 | serine/threonine kinase 24 | 0.0212526 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0212315 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | 0.0209579 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0207944 |
| CEP295 | centrosomal protein 295kDa | 0.0205547 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0205015 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0204838 |
| CKAP2L | cytoskeleton associated protein 2-like | 0.0203606 |
| CUL3 | cullin 3 | 0.0203312 |
| SSH1 | slingshot protein phosphatase 1 | 0.0203033 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0202828 |
| CORO1C | coronin, actin binding protein, 1C | 0.0202711 |
| CENPE | centromere protein E, 312kDa | 0.0200922 |
| KIF23 | kinesin family member 23 | 0.0197185 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.0195976 |
| ALG9 | ALG9, alpha-1,2-mannosyltransferase | 0.019204 |
| PANK3 | pantothenate kinase 3 | 0.0191718 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0190905 |
| TTK | TTK protein kinase | 0.0190831 |
| ATAD2B | ATPase family, AAA domain containing 2B | 0.0190274 |
| PNN | pinin, desmosome associated protein | 0.0189045 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0188897 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0188029 |
| AMBRA1 | autophagy/beclin-1 regulator 1 | 0.018701 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.304488 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.163793 |
| VIM | vimentin | -0.120208 |
| LDHA | lactate dehydrogenase A | -0.0998064 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0985699 |
| TMSB10 | thymosin beta 10 | -0.0981402 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.075632 |
| HMGA2 | high mobility group AT-hook 2 | -0.0735277 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0691632 |
| ANGPTL4 | angiopoietin-like 4 | -0.059995 |
| NDRG1 | N-myc downstream regulated 1 | -0.0583122 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0568066 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0525626 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0524991 |
| PRR16 | proline rich 16 | -0.0511713 |
| PTMA | prothymosin, alpha | -0.051104 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0510329 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0508504 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0506325 |
| AHNAK | AHNAK nucleoprotein | -0.0498866 |
| POTEF | POTE ankyrin domain family, member F | -0.0495266 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0487741 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0474665 |
| RAI14 | retinoic acid induced 14 | -0.0466961 |
| DST | dystonin | -0.044602 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0432791 |
| IGF2 | insulin-like growth factor 2 | -0.0431409 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0415245 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0415048 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0397839 |
| MT2A | metallothionein 2A | -0.0392912 |
| TPI1 | triosephosphate isomerase 1 | -0.039113 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0386543 |
| PLEK2 | pleckstrin 2 | -0.0379965 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0379211 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0372921 |
| ACTG1 | actin gamma 1 | -0.0369505 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0364209 |
| PRSS23 | protease, serine, 23 | -0.0364097 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0360897 |
| ENO1 | enolase 1, (alpha) | -0.0360473 |
| PODXL | podocalyxin-like | -0.0359301 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0356173 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0351088 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0349734 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0348103 |
| PCED1B | PC-esterase domain containing 1B | -0.0346359 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0346214 |
| FMN1 | formin 1 | -0.0345365 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0344823 |
| RPL35A | ribosomal protein L35a | -0.0335342 |
| B2M | beta-2-microglobulin | -0.0331971 |
| S100A6 | S100 calcium binding protein A6 | -0.032712 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0325539 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0318284 |
| RPLP1 | ribosomal protein, large, P1 | -0.0316293 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0314857 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0314601 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.0308132 |
| S100A10 | S100 calcium binding protein A10 | -0.0304605 |
| RPL26 | ribosomal protein L26 | -0.0304217 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0302613 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0301887 |
| MYOF | myoferlin | -0.0299357 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0290604 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0287844 |
| EGFR | epidermal growth factor receptor | -0.0284027 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0283705 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -0.028178 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0279852 |
| CAVIN1 | caveolae associated protein 1 | -0.0275335 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0275293 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0273038 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.026898 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0268715 |
| INTS6 | integrator complex subunit 6 | -0.02687 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0268505 |
| IER3 | immediate early response 3 | -0.0265605 |
| ZFHX3 | zinc finger homeobox 3 | -0.0265433 |
| EGR1 | early growth response 1 | -0.0263347 |
| PURA | purine-rich element binding protein A | -0.0263217 |
| UBB | ubiquitin B | -0.0259812 |
| HLA-B | major histocompatibility complex, class I, B | -0.0259518 |
| PARD3 | par-3 family cell polarity regulator | -0.0258617 |
| ASPH | aspartate beta-hydroxylase | -0.0255431 |
| NALCN | sodium leak channel, non selective | -0.0253442 |
| RPL9 | ribosomal protein L9 | -0.0251563 |
| FTL | ferritin, light polypeptide | -0.0250774 |
| RPS13 | ribosomal protein S13 | -0.0250758 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | -0.025009 |
| GPC6 | glypican 6 | -0.0249375 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0249054 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0247728 |
| PTK2 | protein tyrosine kinase 2 | -0.0247088 |
| RPS6 | ribosomal protein S6 | -0.0247078 |
| COL5A1 | collagen, type V, alpha 1 | -0.024582 |
| RPS21 | ribosomal protein S21 | -0.0245719 |
| THBS1 | thrombospondin 1 | -0.0241183 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0240166 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0236446 |