| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Balsalazide (sodium hydrate) perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Balsalazide (sodium hydrate)_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH13 | cadherin 13 | 0.170306 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.163295 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.143062 |
| COL5A1 | collagen, type V, alpha 1 | 0.140929 |
| AHNAK | AHNAK nucleoprotein | 0.116752 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.115236 |
| PODXL | podocalyxin-like | 0.107282 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0909418 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0716823 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0709212 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0665682 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0637965 |
| EGFR | epidermal growth factor receptor | 0.0630283 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0616715 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0600486 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.0594637 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0589373 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0586786 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0575047 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0574571 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0567748 |
| FN1 | fibronectin 1 | 0.05354 |
| CALR | calreticulin | 0.0532041 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0518333 |
| FLNA | filamin A, alpha | 0.0502864 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0485121 |
| NAV2 | neuron navigator 2 | 0.0479921 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0477263 |
| FSTL1 | follistatin-like 1 | 0.0464298 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0464229 |
| DCLK2 | doublecortin-like kinase 2 | 0.0427517 |
| CD109 | CD109 molecule | 0.0410199 |
| HDAC9 | histone deacetylase 9 | 0.0408705 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0407412 |
| ASPH | aspartate beta-hydroxylase | 0.0404127 |
| MSI2 | musashi RNA-binding protein 2 | 0.0399956 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0398157 |
| EFNA5 | ephrin-A5 | 0.0380197 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0378043 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0373393 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0372549 |
| FLNB | filamin B, beta | 0.0372136 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0357365 |
| DSPP | dentin sialophosphoprotein | 0.0353597 |
| ENO1 | enolase 1, (alpha) | 0.0339394 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0334903 |
| TPM3 | tropomyosin 3 | 0.0334423 |
| DST | dystonin | 0.0309631 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0306159 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0294777 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.029365 |
| MSN | moesin | 0.0292205 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | 0.0291339 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0290263 |
| C1D | C1D nuclear receptor corepressor | 0.0287173 |
| POTEF | POTE ankyrin domain family, member F | 0.0287151 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0284363 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0277403 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0275862 |
| RHOA | ras homolog family member A | 0.0275702 |
| JUN | jun proto-oncogene | 0.0271964 |
| PLEC | plectin | 0.026666 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.026605 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0259331 |
| L1CAM | L1 cell adhesion molecule | 0.0257619 |
| PLXNA2 | plexin A2 | 0.0253388 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0252923 |
| UBC | ubiquitin C | 0.0249497 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0248572 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0245639 |
| COPA | coatomer protein complex, subunit alpha | 0.0245313 |
| FMN2 | formin 2 | 0.0243301 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 0.0242019 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0239861 |
| MAP1B | microtubule-associated protein 1B | 0.0239116 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0237237 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0231532 |
| FLT1 | fms-related tyrosine kinase 1 | 0.0230616 |
| PKM | pyruvate kinase, muscle | 0.0229318 |
| EZR | ezrin | 0.0227719 |
| NAV1 | neuron navigator 1 | 0.0227567 |
| ANKRD30B | ankyrin repeat domain 30B | 0.022235 |
| MYOF | myoferlin | 0.0222094 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0222012 |
| SMAD3 | SMAD family member 3 | 0.0218846 |
| SORBS2 | sorbin and SH3 domain containing 2 | 0.0212885 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0211913 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0211539 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0209948 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | 0.0209227 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0206723 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0206259 |
| ULK1 | unc-51 like autophagy activating kinase 1 | 0.0203767 |
| CANX | calnexin | 0.0201579 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0201379 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0200816 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0200371 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0198988 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0195913 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0189483 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.194827 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.185672 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.180257 |
| FBN1 | fibrillin 1 | -0.16101 |
| TMSB10 | thymosin beta 10 | -0.13618 |
| COL1A2 | collagen, type I, alpha 2 | -0.111217 |
| VIM | vimentin | -0.102727 |
| PLAT | plasminogen activator, tissue | -0.0996063 |
| LOX | lysyl oxidase | -0.0856985 |
| B2M | beta-2-microglobulin | -0.0796839 |
| HLA-B | major histocompatibility complex, class I, B | -0.0793007 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0705595 |
| GPC6 | glypican 6 | -0.0596065 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0579539 |
| STC1 | stanniocalcin 1 | -0.0557604 |
| COL3A1 | collagen, type III, alpha 1 | -0.0535067 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0523386 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0516137 |
| S100A10 | S100 calcium binding protein A10 | -0.0510042 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0490013 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0453043 |
| SBF2 | SET binding factor 2 | -0.0438883 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0437638 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0414942 |
| NDRG1 | N-myc downstream regulated 1 | -0.0410824 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0407326 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0407324 |
| MX2 | MX dynamin-like GTPase 2 | -0.040529 |
| HLA-C | major histocompatibility complex, class I, C | -0.0404108 |
| MYADM | myeloid-associated differentiation marker | -0.0400721 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0388501 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0386658 |
| LOXL2 | lysyl oxidase-like 2 | -0.038219 |
| MT1X | metallothionein 1X | -0.0380444 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0360507 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0360063 |
| GLIS3 | GLIS family zinc finger 3 | -0.0359538 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0358654 |
| SQSTM1 | sequestosome 1 | -0.035207 |
| COL5A2 | collagen, type V, alpha 2 | -0.0343028 |
| CD44 | CD44 molecule (Indian blood group) | -0.0342377 |
| RBM25 | RNA binding motif protein 25 | -0.0338422 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0337671 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0333214 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0332827 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0332446 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0332057 |
| KIFAP3 | kinesin-associated protein 3 | -0.0331936 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0328806 |
| MAP4 | microtubule-associated protein 4 | -0.0328578 |
| S100A6 | S100 calcium binding protein A6 | -0.0328257 |
| FRMD5 | FERM domain containing 5 | -0.0313369 |
| ATP13A3 | ATPase type 13A3 | -0.0307509 |
| HLA-E | major histocompatibility complex, class I, E | -0.0306606 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0305967 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0305206 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0293862 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0292019 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0288329 |
| CLU | clusterin | -0.0287918 |
| TMOD1 | tropomodulin 1 | -0.0281732 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0273658 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0270285 |
| CD99 | CD99 molecule | -0.0268524 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.026627 |
| CAVIN1 | caveolae associated protein 1 | -0.0266082 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0265498 |
| PTMA | prothymosin, alpha | -0.026217 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0260789 |
| LMNA | lamin A/C | -0.0254757 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0253975 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0253662 |
| NKTR | natural killer cell triggering receptor | -0.0250155 |
| H3-3B | H3.3 histone B | -0.0246608 |
| ANKRD10 | ankyrin repeat domain 10 | -0.024624 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0245992 |
| SVIL | supervillin | -0.0242403 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0242344 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0240572 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0240363 |
| OPTN | optineurin | -0.0239232 |
| EHBP1 | EH domain binding protein 1 | -0.0236842 |
| RAI14 | retinoic acid induced 14 | -0.0235818 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0235584 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0235485 |
| RPS24 | ribosomal protein S24 | -0.0233124 |
| S100A4 | S100 calcium binding protein A4 | -0.0232558 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0232212 |
| TDRD7 | tudor domain containing 7 | -0.02317 |
| MEIS2 | Meis homeobox 2 | -0.0231148 |
| PXDN | peroxidasin | -0.0230863 |
| RASA2 | RAS p21 protein activator 2 | -0.0228898 |
| ADAR | adenosine deaminase, RNA-specific | -0.0227249 |
| NF1 | neurofibromin 1 | -0.0221255 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | -0.0220965 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0220377 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0219353 |
| RPS19 | ribosomal protein S19 | -0.0218947 |
| MTSS1 | metastasis suppressor 1 | -0.0216906 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0205664 |
