| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Balsalazide (sodium hydrate) perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Balsalazide (sodium hydrate)_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCBP2 | poly(rC) binding protein 2 | 0.0958211 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0618502 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0596764 |
| CCN2 | cellular communication network factor 2 | 0.0583113 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0566685 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0559473 |
| POTEF | POTE ankyrin domain family, member F | 0.0554103 |
| CEP192 | centrosomal protein 192kDa | 0.0549515 |
| XPO1 | exportin 1 | 0.0537048 |
| TPM3 | tropomyosin 3 | 0.0526499 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0526119 |
| CCNL1 | cyclin L1 | 0.0523206 |
| ZNF292 | zinc finger protein 292 | 0.0522513 |
| YAP1 | Yes-associated protein 1 | 0.0516319 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0510989 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0489421 |
| PCM1 | pericentriolar material 1 | 0.0477988 |
| ZNF638 | zinc finger protein 638 | 0.0475148 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0467878 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0463182 |
| USP34 | ubiquitin specific peptidase 34 | 0.0454377 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0452409 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0432283 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0397656 |
| RBM39 | RNA binding motif protein 39 | 0.0395085 |
| BRD2 | bromodomain containing 2 | 0.0391128 |
| YBX1 | Y box binding protein 1 | 0.0388951 |
| DST | dystonin | 0.0388308 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0382518 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0381528 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0380462 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0378905 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0377425 |
| VMP1 | vacuole membrane protein 1 | 0.0374344 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0370912 |
| ECT2 | epithelial cell transforming 2 | 0.036704 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0363085 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0362058 |
| YEATS2 | YEATS domain containing 2 | 0.0360303 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0359278 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0351119 |
| TBK1 | TANK-binding kinase 1 | 0.0349407 |
| RBM25 | RNA binding motif protein 25 | 0.0345864 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.03442 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0343675 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0338075 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0334564 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0333529 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0331581 |
| PTMS | parathymosin | 0.0327056 |
| CCDC88A | coiled-coil domain containing 88A | 0.0326123 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0325229 |
| WWOX | WW domain containing oxidoreductase | 0.0323048 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0316779 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0315866 |
| EPHA6 | EPH receptor A6 | 0.0312283 |
| HELZ | helicase with zinc finger | 0.0311394 |
| PRKCI | protein kinase C, iota | 0.031029 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0306432 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0303807 |
| RPL3 | ribosomal protein L3 | 0.0298206 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0298193 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0296233 |
| ARF4 | ADP-ribosylation factor 4 | 0.0295251 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0295044 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0289857 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.0286589 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0286507 |
| TPR | translocated promoter region, nuclear basket protein | 0.0284786 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0283029 |
| EZR | ezrin | 0.0282409 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0282332 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0282312 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0279971 |
| MKI67 | marker of proliferation Ki-67 | 0.0276573 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0274701 |
| FUS | FUS RNA binding protein | 0.027371 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0273212 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0270782 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.026901 |
| RRM2 | ribonucleotide reductase M2 | 0.0268991 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0266484 |
| WDR43 | WD repeat domain 43 | 0.0266198 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0266094 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0265657 |
| MATR3 | matrin 3 | 0.0265165 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0263338 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.025871 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0257194 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0256837 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0253074 |
| CPOX | coproporphyrinogen oxidase | 0.0251944 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0251786 |
| MED13 | mediator complex subunit 13 | 0.0250944 |
| ATP11A | ATPase, class VI, type 11A | 0.0249748 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0248501 |
| SMYD3 | SET and MYND domain containing 3 | 0.0247353 |
| OGA | O-GlcNAcase | 0.0245553 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0244748 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0244583 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.220299 |
| VIM | vimentin | -0.165285 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.152374 |
| HMGA2 | high mobility group AT-hook 2 | -0.144138 |
| TMSB10 | thymosin beta 10 | -0.108687 |
| EHBP1 | EH domain binding protein 1 | -0.0918628 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0885988 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0721754 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0695094 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0666001 |
| ZNF804A | zinc finger protein 804A | -0.0602496 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.057958 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0572915 |
| PCDH7 | protocadherin 7 | -0.0571282 |
| ASPH | aspartate beta-hydroxylase | -0.056861 |
| BCHE | butyrylcholinesterase | -0.0531916 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0526522 |
| CLDN1 | claudin 1 | -0.0508492 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0506762 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0495658 |
| RASAL2 | RAS protein activator like 2 | -0.0490799 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0469777 |
| RPS24 | ribosomal protein S24 | -0.0456766 |
| NABP1 | nucleic acid binding protein 1 | -0.045326 |
| NHSL1 | NHS-like 1 | -0.0452965 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0452848 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0452456 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0414901 |
| RPL26 | ribosomal protein L26 | -0.0393409 |
| RPLP0 | ribosomal protein, large, P0 | -0.0352532 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0350975 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0342099 |
| INTS6 | integrator complex subunit 6 | -0.0340419 |
| RPL34 | ribosomal protein L34 | -0.0337624 |
| MTAP | methylthioadenosine phosphorylase | -0.0336173 |
| PTMA | prothymosin, alpha | -0.033115 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0328982 |
| RPL19 | ribosomal protein L19 | -0.0325848 |
| PCDH9 | protocadherin 9 | -0.0325014 |
| ACTG1 | actin gamma 1 | -0.031931 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0314678 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0306926 |
| CUX1 | cut-like homeobox 1 | -0.0304706 |
| S100A10 | S100 calcium binding protein A10 | -0.0303769 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0298041 |
| GNAS | GNAS complex locus | -0.0293786 |
| NLGN1 | neuroligin 1 | -0.0291801 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0279427 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0271899 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.027084 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0266259 |
| SYT1 | synaptotagmin I | -0.0266036 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0262519 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0261653 |
| RPL35A | ribosomal protein L35a | -0.0259398 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0258067 |
| S100A6 | S100 calcium binding protein A6 | -0.0255985 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0252616 |
| EPHA5 | EPH receptor A5 | -0.0252367 |
| RPS8 | ribosomal protein S8 | -0.0249813 |
| RPL23 | ribosomal protein L23 | -0.0243638 |
| RPL9 | ribosomal protein L9 | -0.0241317 |
| KLF6 | Kruppel-like factor 6 | -0.0239975 |
| MMP12 | matrix metallopeptidase 12 | -0.0239355 |
| RPL31 | ribosomal protein L31 | -0.0235087 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | -0.0234583 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.023254 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0231255 |
| RPS3 | ribosomal protein S3 | -0.0229607 |
| RPL37 | ribosomal protein L37 | -0.0228433 |
| RPS27A | ribosomal protein S27a | -0.0227934 |
| RPL27 | ribosomal protein L27 | -0.0221953 |
| RAB10 | RAB10, member RAS oncogene family | -0.0220784 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0218935 |
| PCNX4 | pecanex 4 | -0.0216044 |
| FAM110C | family with sequence similarity 110, member C | -0.0215129 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0215111 |
| LRRC23 | leucine rich repeat containing 23 | -0.021394 |
| NACA | nascent polypeptide-associated complex alpha subunit | -0.0212292 |
| BRI3BP | BRI3 binding protein | -0.0205754 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0204569 |
| AHNAK | AHNAK nucleoprotein | -0.0202047 |
| GPATCH8 | G patch domain containing 8 | -0.0201656 |
| STMP1 | short transmembrane mitochondrial protein 1 | -0.0200602 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0195714 |
| COMMD10 | COMM domain containing 10 | -0.0194797 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0193728 |
| RPS15 | ribosomal protein S15 | -0.0192505 |
| RPL12 | ribosomal protein L12 | -0.0192209 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0190601 |
| CDK12 | cyclin-dependent kinase 12 | -0.0190432 |
| TRAF3 | TNF receptor-associated factor 3 | -0.018754 |
| RPS20 | ribosomal protein S20 | -0.0185776 |
| RPS25 | ribosomal protein S25 | -0.0182967 |
| RSU1 | Ras suppressor protein 1 | -0.0182734 |
| RPL38 | ribosomal protein L38 | -0.0181866 |
| RPS12 | ribosomal protein S12 | -0.018186 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0181841 |
| R3HDM2 | R3H domain containing 2 | -0.0181718 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0179405 |
