| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Balsalazide (sodium hydrate) perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Balsalazide (sodium hydrate)_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FRMD4A | FERM domain containing 4A | 0.160958 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.124099 |
| NAV2 | neuron navigator 2 | 0.0582141 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.052151 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0513915 |
| GPC6 | glypican 6 | 0.0446095 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0395993 |
| SMAD3 | SMAD family member 3 | 0.028319 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0275973 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.025498 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0254488 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0250539 |
| VEGFA | vascular endothelial growth factor A | 0.0241842 |
| PLEC | plectin | 0.0234294 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0233692 |
| FAM13A | family with sequence similarity 13, member A | 0.0225907 |
| RNF213 | ring finger protein 213 | 0.0220475 |
| ATP13A3 | ATPase type 13A3 | 0.0208043 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0195916 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0195594 |
| COL5A1 | collagen, type V, alpha 1 | 0.0187835 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0185548 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0185191 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | 0.0179353 |
| GPC5 | glypican 5 | 0.0177645 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0176261 |
| EHBP1 | EH domain binding protein 1 | 0.0174708 |
| HPCAL1 | hippocalcin-like 1 | 0.0173736 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0173068 |
| NDRG1 | N-myc downstream regulated 1 | 0.0172732 |
| SFTPA2 | surfactant protein A2 | 0.0172216 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0170592 |
| APOL1 | apolipoprotein L, 1 | 0.0167743 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0167174 |
| CA12 | carbonic anhydrase XII | 0.0166914 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0165824 |
| AHNAK | AHNAK nucleoprotein | 0.0164785 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0161642 |
| DAPK1 | death-associated protein kinase 1 | 0.0160739 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0159909 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0156854 |
| FMNL2 | formin-like 2 | 0.0156458 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0153098 |
| RAI14 | retinoic acid induced 14 | 0.0152822 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0149614 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0147731 |
| FSTL1 | follistatin-like 1 | 0.0144839 |
| TGM2 | transglutaminase 2 | 0.0144375 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0144016 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.0143805 |
| ANO6 | anoctamin 6 | 0.0140025 |
| LOXL2 | lysyl oxidase-like 2 | 0.0139397 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0139205 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.013612 |
| EFNA5 | ephrin-A5 | 0.0134427 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0133773 |
| NEK6 | NIMA-related kinase 6 | 0.0133509 |
| UBE3C | ubiquitin protein ligase E3C | 0.0132709 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0132 |
| BNC2 | basonuclin 2 | 0.0131001 |
| PRKCA | protein kinase C, alpha | 0.0128446 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0126656 |
| EXOC4 | exocyst complex component 4 | 0.0125997 |
| MYOF | myoferlin | 0.012197 |
| HDLBP | high density lipoprotein binding protein | 0.0121889 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0121708 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0121602 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0121321 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0120825 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0119948 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0119919 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0118517 |
| FRMD5 | FERM domain containing 5 | 0.0115278 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0114412 |
| TCF12 | transcription factor 12 | 0.0114335 |
| PTK2 | protein tyrosine kinase 2 | 0.0114258 |
| RUNX2 | runt-related transcription factor 2 | 0.0114245 |
| SLC22A3 | solute carrier family 22 (organic cation transporter), member 3 | 0.0114121 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0113656 |
| CTBP2 | C-terminal binding protein 2 | 0.0113109 |
| FNIP1 | folliculin interacting protein 1 | 0.0112747 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0112732 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | 0.0111998 |
| FAM219A | family with sequence similarity 219, member A | 0.0111867 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0111381 |
| SEPTIN9 | septin 9 | 0.0110839 |
| TNS1 | tensin 1 | 0.0110319 |
| C1D | C1D nuclear receptor corepressor | 0.0108463 |
| GAD1 | glutamate decarboxylase 1 (brain, 67kDa) | 0.0107885 |
| TMEM65 | transmembrane protein 65 | 0.0107839 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0106341 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | 0.0105959 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0105032 |
| FAT1 | FAT atypical cadherin 1 | 0.0103248 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0101943 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0101866 |
| EGFR | epidermal growth factor receptor | 0.0101111 |
| DST | dystonin | 0.0101005 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0100318 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0100174 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.158714 |
| VIM | vimentin | -0.148926 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.136436 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.125172 |
| TMSB10 | thymosin beta 10 | -0.113374 |
| CCL2 | chemokine (C-C motif) ligand 2 | -0.0995655 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0885434 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0785701 |
| B2M | beta-2-microglobulin | -0.0763658 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0748538 |
| CSF1 | colony stimulating factor 1 (macrophage) | -0.0734445 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0701371 |
| PFN1 | profilin 1 | -0.0693382 |
| ASPH | aspartate beta-hydroxylase | -0.0680685 |
| PTMA | prothymosin, alpha | -0.0640198 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0623691 |
| RPS6 | ribosomal protein S6 | -0.0608581 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0601018 |
| MT2A | metallothionein 2A | -0.0594339 |
| TXNRD1 | thioredoxin reductase 1 | -0.0534738 |
| RPL23 | ribosomal protein L23 | -0.0525586 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0515639 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0509587 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.046975 |
| RPL35A | ribosomal protein L35a | -0.0466781 |
| RPS8 | ribosomal protein S8 | -0.0464796 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0450792 |
| UBC | ubiquitin C | -0.0438548 |
| RTN4 | reticulon 4 | -0.0435119 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0434009 |
| RPLP2 | ribosomal protein, large, P2 | -0.0408772 |
| MAP1B | microtubule-associated protein 1B | -0.0401205 |
| PKM | pyruvate kinase, muscle | -0.0393377 |
| CBX3 | chromobox homolog 3 | -0.0391561 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.038229 |
| S100A10 | S100 calcium binding protein A10 | -0.0380554 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0375019 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0371691 |
| TUBA1B | tubulin, alpha 1b | -0.0370732 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0369365 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0369183 |
| RPS19 | ribosomal protein S19 | -0.0361151 |
| CENPF | centromere protein F, 350/400kDa | -0.0349422 |
| RPL9 | ribosomal protein L9 | -0.0347969 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0339841 |
| HLA-B | major histocompatibility complex, class I, B | -0.0339721 |
| G0S2 | G0/G1 switch 2 | -0.0328621 |
| RPS5 | ribosomal protein S5 | -0.0328403 |
| RPLP1 | ribosomal protein, large, P1 | -0.032247 |
| LITAF | lipopolysaccharide-induced TNF factor | -0.03128 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0312107 |
| CD44 | CD44 molecule (Indian blood group) | -0.0309702 |
| POTEF | POTE ankyrin domain family, member F | -0.0308736 |
| RPS24 | ribosomal protein S24 | -0.0308688 |
| RPL12 | ribosomal protein L12 | -0.0307029 |
| RPL19 | ribosomal protein L19 | -0.0306562 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0304759 |
| RPS13 | ribosomal protein S13 | -0.0304198 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0302338 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0291732 |
| RPS27A | ribosomal protein S27a | -0.0291556 |
| MYADM | myeloid-associated differentiation marker | -0.0289356 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.028834 |
| NOP58 | NOP58 ribonucleoprotein | -0.0286144 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0285221 |
| SON | SON DNA binding protein | -0.0280782 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0274262 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0273894 |
| RPL8 | ribosomal protein L8 | -0.0272509 |
| TPM4 | tropomyosin 4 | -0.0267862 |
| TAGLN2 | transgelin 2 | -0.0266923 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0264437 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0262851 |
| SEPTIN7 | septin 7 | -0.0259584 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0257596 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0255158 |
| CXXC1 | CXXC finger protein 1 | -0.0254251 |
| DSTN | destrin (actin depolymerizing factor) | -0.0252043 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0247932 |
| RPL34 | ribosomal protein L34 | -0.0245906 |
| HMGB1 | high mobility group box 1 | -0.0244112 |
| RPS12 | ribosomal protein S12 | -0.0243662 |
| S100A6 | S100 calcium binding protein A6 | -0.0243537 |
| GDF15 | growth differentiation factor 15 | -0.0243498 |
| RPL31 | ribosomal protein L31 | -0.0241631 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0240977 |
| H3-3B | H3.3 histone B | -0.0239094 |
| RPL26 | ribosomal protein L26 | -0.0237543 |
| PLK2 | polo-like kinase 2 | -0.023366 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0233534 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0233406 |
| NUCB2 | nucleobindin 2 | -0.0231371 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0230381 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0227545 |
| RPS23 | ribosomal protein S23 | -0.0227227 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.022666 |
| RPL28 | ribosomal protein L28 | -0.0226272 |
| JUN | jun proto-oncogene | -0.0224267 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0224265 |
| RBM25 | RNA binding motif protein 25 | -0.0223635 |