| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Balsalazide (sodium hydrate) perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Balsalazide (sodium hydrate)_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SMAD3 | SMAD family member 3 | 0.128291 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.123889 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.120593 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0776849 |
| AHNAK | AHNAK nucleoprotein | 0.0590118 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0525257 |
| PDE10A | phosphodiesterase 10A | 0.052111 |
| FLNB | filamin B, beta | 0.0485518 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0465013 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0445438 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0431672 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.043088 |
| FMNL2 | formin-like 2 | 0.0430728 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0426959 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0422699 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.040305 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0395787 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0391175 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0375432 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0367794 |
| SPAG9 | sperm associated antigen 9 | 0.0361913 |
| PLEC | plectin | 0.036089 |
| NAV2 | neuron navigator 2 | 0.035112 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0348348 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.034303 |
| RPL4 | ribosomal protein L4 | 0.0329114 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0322399 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0320427 |
| CA12 | carbonic anhydrase XII | 0.0319404 |
| OGA | O-GlcNAcase | 0.030762 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0304664 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0296574 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0294619 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0288392 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0286053 |
| HELZ | helicase with zinc finger | 0.0285127 |
| TNS1 | tensin 1 | 0.0275224 |
| TCIM | transcriptional and immune response regulator | 0.0273561 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0272818 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0262691 |
| FAM13A | family with sequence similarity 13, member A | 0.026046 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0256126 |
| APP | amyloid beta (A4) precursor protein | 0.0254759 |
| FNDC3B | fibronectin type III domain containing 3B | 0.025335 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.025324 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0251527 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0251067 |
| C1D | C1D nuclear receptor corepressor | 0.0249465 |
| SEPTIN9 | septin 9 | 0.0241084 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0240429 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.0239331 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0237778 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0237355 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0237217 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0234305 |
| CORO1C | coronin, actin binding protein, 1C | 0.0230321 |
| USP3 | ubiquitin specific peptidase 3 | 0.0228107 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0227861 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0225543 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0221506 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.0220915 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0220422 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | 0.0220367 |
| TGM2 | transglutaminase 2 | 0.0216852 |
| PFKP | phosphofructokinase, platelet | 0.0210893 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0210853 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0208844 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0208189 |
| PDZD8 | PDZ domain containing 8 | 0.0206829 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0205638 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | 0.0204347 |
| MYO10 | myosin X | 0.0204047 |
| PRKCE | protein kinase C, epsilon | 0.0202805 |
| YEATS2 | YEATS domain containing 2 | 0.0201808 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0199917 |
| LOXL2 | lysyl oxidase-like 2 | 0.0197276 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0196335 |
| SMYD3 | SET and MYND domain containing 3 | 0.0195044 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.019428 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0193905 |
| ANO6 | anoctamin 6 | 0.0191533 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0190594 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0189318 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0188801 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0188117 |
| ANXA2 | annexin A2 | 0.0187111 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0182747 |
| HIP1 | huntingtin interacting protein 1 | 0.0181405 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0181089 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0180163 |
| NGLY1 | N-glycanase 1 | 0.0179943 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0179677 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0177217 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0175566 |
| ADAR | adenosine deaminase, RNA-specific | 0.0174562 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0172632 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0172082 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0172065 |
| FA2H | fatty acid 2-hydroxylase | 0.0171272 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0170905 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.260174 |
| VIM | vimentin | -0.125697 |
| MT2A | metallothionein 2A | -0.109806 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0922777 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0894253 |
| MT1X | metallothionein 1X | -0.0803229 |
| KRT81 | keratin 81, type II | -0.0753389 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.0647578 |
| RPS19 | ribosomal protein S19 | -0.0548525 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0523941 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0480944 |
| PFN1 | profilin 1 | -0.0466062 |
| S100A6 | S100 calcium binding protein A6 | -0.0461373 |
| ASPH | aspartate beta-hydroxylase | -0.0449444 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0448218 |
| ACTG1 | actin gamma 1 | -0.0443972 |
| MYADM | myeloid-associated differentiation marker | -0.0442499 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0432472 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.042825 |
| RPS6 | ribosomal protein S6 | -0.0426379 |
| EHBP1 | EH domain binding protein 1 | -0.0400735 |
| HMGA1 | high mobility group AT-hook 1 | -0.040044 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0393471 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0371303 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0365548 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0359402 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0353462 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0352314 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0318127 |
| LMNA | lamin A/C | -0.0312928 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0307353 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0307278 |
| MAP1B | microtubule-associated protein 1B | -0.0297487 |
| RPL23 | ribosomal protein L23 | -0.0296904 |
| NDRG1 | N-myc downstream regulated 1 | -0.0291692 |
| RPLP1 | ribosomal protein, large, P1 | -0.0291353 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0287154 |
| CCDC88A | coiled-coil domain containing 88A | -0.0285607 |
| RPS24 | ribosomal protein S24 | -0.0282611 |
| FTL | ferritin, light polypeptide | -0.0281473 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.0280549 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.026983 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.026636 |
| EGR1 | early growth response 1 | -0.0247939 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0246041 |
| S100A10 | S100 calcium binding protein A10 | -0.0241295 |
| ASTN2 | astrotactin 2 | -0.0239197 |
| B2M | beta-2-microglobulin | -0.0238151 |
| HMGA2 | high mobility group AT-hook 2 | -0.0238124 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0234501 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0232666 |
| BPTF | bromodomain PHD finger transcription factor | -0.0229618 |
| PRKCA | protein kinase C, alpha | -0.0228328 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0227447 |
| PTMA | prothymosin, alpha | -0.0227389 |
| KYNU | kynureninase | -0.0225472 |
| RPL18 | ribosomal protein L18 | -0.0222537 |
| RPL12 | ribosomal protein L12 | -0.0222468 |
| PERP | PERP, TP53 apoptosis effector | -0.0220459 |
| RPL26 | ribosomal protein L26 | -0.022029 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0216404 |
| TPI1 | triosephosphate isomerase 1 | -0.0211963 |
| RPLP2 | ribosomal protein, large, P2 | -0.0207815 |
| RPL9 | ribosomal protein L9 | -0.0206187 |
| H3-3B | H3.3 histone B | -0.0204995 |
| RPL32 | ribosomal protein L32 | -0.0203385 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0202463 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.01962 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0196116 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0195272 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0194395 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0193468 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0192859 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0191888 |
| RPS21 | ribosomal protein S21 | -0.0190317 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0190078 |
| RPL37A | ribosomal protein L37a | -0.0186871 |
| RPS8 | ribosomal protein S8 | -0.0186532 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0186279 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0180757 |
| RPL36A | ribosomal protein L36a | -0.018008 |
| NRG1 | neuregulin 1 | -0.0179871 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0178811 |
| CBX3 | chromobox homolog 3 | -0.0178744 |
| HLA-B | major histocompatibility complex, class I, B | -0.0178064 |
| AUTS2 | autism susceptibility candidate 2 | -0.0177118 |
| RPS14 | ribosomal protein S14 | -0.017649 |
| ZFHX3 | zinc finger homeobox 3 | -0.0175302 |
| CAPNS1 | calpain, small subunit 1 | -0.0174833 |
| SLC25A51 | solute carrier family 25, member 51 | -0.0173503 |
| S100A11 | S100 calcium binding protein A11 | -0.0171716 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0171242 |
| NRP1 | neuropilin 1 | -0.016844 |
| RPS16 | ribosomal protein S16 | -0.0166936 |
| RPL35A | ribosomal protein L35a | -0.0166478 |
| FBXO11 | F-box protein 11 | -0.0166077 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0165527 |
| RPL35 | ribosomal protein L35 | -0.016243 |
| RPL19 | ribosomal protein L19 | -0.0161295 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0161188 |
