Balsalazide (sodium hydrate)_AN3 CA Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Balsalazide (sodium hydrate) perturbation in AN3 CA cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Balsalazide (sodium hydrate)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
MEST mesoderm specific transcript 0.0479596
FGFR1 fibroblast growth factor receptor 1 0.0463894
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0446605
TOP2B topoisomerase (DNA) II beta 180kDa 0.0409099
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0409039
PDE4D phosphodiesterase 4D, cAMP-specific 0.040814
PDE10A phosphodiesterase 10A 0.0394754
VEGFA vascular endothelial growth factor A 0.0393546
GSE1 Gse1 coiled-coil protein 0.0322941
RPL3 ribosomal protein L3 0.0322203
EEF2 eukaryotic translation elongation factor 2 0.0257808
RPL4 ribosomal protein L4 0.0251492
PDE4B phosphodiesterase 4B, cAMP-specific 0.0245624
QKI QKI, KH domain containing, RNA binding 0.023582
PRELID2 PRELI domain containing 2 0.0229369
TMSB4X thymosin beta 4, X-linked 0.0228991
HSPA8 heat shock 70kDa protein 8 0.0227919
MATR3 matrin 3 0.0226044
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0200612
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.0199883
PCDH7 protocadherin 7 0.0199665
ITGAV integrin, alpha V 0.0199103
RAD51B RAD51 paralog B 0.0197184
MED13L mediator complex subunit 13-like 0.0196551
YEATS2 YEATS domain containing 2 0.0193688
ANO6 anoctamin 6 0.0187726
FAM120B family with sequence similarity 120B 0.0185065
OGA O-GlcNAcase 0.0181504
ADGRA3 adhesion G protein-coupled receptor A3 0.0181246
MACF1 microtubule-actin crosslinking factor 1 0.0178283
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0175339
SFTPA2 surfactant protein A2 0.0170688
FGFR2 fibroblast growth factor receptor 2 0.0159919
FTH1 ferritin, heavy polypeptide 1 0.0157862
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.0153621
BHLHE40 basic helix-loop-helix family, member e40 0.0152205
ARRDC3 arrestin domain containing 3 0.0151529
PAXBP1 PAX3 and PAX7 binding protein 1 0.015079
USP24 ubiquitin specific peptidase 24 0.0149833
OSBPL10 oxysterol binding protein-like 10 0.0149623
BCOR BCL6 corepressor 0.0148929
EIF4H eukaryotic translation initiation factor 4H 0.0148729
ARHGAP21 Rho GTPase activating protein 21 0.0148714
MMP16 matrix metallopeptidase 16 (membrane-inserted) 0.0144319
NCKAP1 NCK-associated protein 1 0.0141404
MNAT1 MNAT CDK-activating kinase assembly factor 1 0.0140776
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0139602
ZNF292 zinc finger protein 292 0.0138924
HOXA3 homeobox A3 0.0138069
PDK4 pyruvate dehydrogenase kinase, isozyme 4 0.0137402
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) 0.0135921
PTBP2 polypyrimidine tract binding protein 2 0.0134936
MED14 mediator complex subunit 14 0.013473
PRKCE protein kinase C, epsilon 0.0132929
USP3 ubiquitin specific peptidase 3 0.0132917
SEPTIN11 septin 11 0.013184
GTF2I general transcription factor IIi 0.0131367
KDM5C lysine (K)-specific demethylase 5C 0.0130173
KLHDC10 kelch domain containing 10 0.0129529
ATP11A ATPase, class VI, type 11A 0.0129254
NUBPL nucleotide binding protein-like 0.0129107
MYEF2 myelin expression factor 2 0.0128865
RPS3A ribosomal protein S3A 0.012866
VGLL4 vestigial-like family member 4 0.0126501
NCOR2 nuclear receptor corepressor 2 0.0125864
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 0.0124452
RPS18 ribosomal protein S18 0.0122857
FAR1 fatty acyl CoA reductase 1 0.0122419
PRKN parkin RBR E3 ubiquitin protein ligase 0.0121958
USP9X ubiquitin specific peptidase 9, X-linked 0.0119745
TSHZ2 teashirt zinc finger homeobox 2 0.0118359
TAC4 tachykinin 4 (hemokinin) 0.0116639
SGCE sarcoglycan, epsilon 0.0115186
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 0.0114908
ANKIB1 ankyrin repeat and IBR domain containing 1 0.0114667
UBQLN1 ubiquilin 1 0.0113809
CAPRIN1 cell cycle associated protein 1 0.0113684
AHNAK AHNAK nucleoprotein 0.0112772
TCF20 transcription factor 20 (AR1) 0.0111773
STX8 syntaxin 8 0.0110901
AKR1C2 aldo-keto reductase family 1, member C2 0.0110816
TRIM33 tripartite motif containing 33 0.0110453
LUC7L2 LUC7-like 2 (S. cerevisiae) 0.0110049
ZNF608 zinc finger protein 608 0.0109923
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 0.0108907
ATXN7 ataxin 7 0.0108555
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae) 0.0107931
MAML3 mastermind-like 3 (Drosophila) 0.0107507
SKIL SKI-like proto-oncogene 0.0107471
KDM1A lysine (K)-specific demethylase 1A 0.0106247
ARID1B AT rich interactive domain 1B (SWI1-like) 0.0105722
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein 0.0105182
SNX13 sorting nexin 13 0.0104319
BTBD3 BTB (POZ) domain containing 3 0.0103347
ARMH3 armadillo like helical domain containing 3 0.01033
KANK1 KN motif and ankyrin repeat domains 1 0.0103078
USP32 ubiquitin specific peptidase 32 0.0102624
TSNAX translin-associated factor X 0.0102242
BIRC2 baculoviral IAP repeat containing 2 0.0101929
HSF2 heat shock transcription factor 2 0.0101839

decreased expression

Symbol Name Standardized Value
VIM vimentin -0.198548
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.102267
PTMA prothymosin, alpha -0.0908218
RPS6 ribosomal protein S6 -0.0871036
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0726566
CENPF centromere protein F, 350/400kDa -0.0709958
CADM2 cell adhesion molecule 2 -0.0689562
MGP matrix Gla protein -0.0603518
TMSB10 thymosin beta 10 -0.0548965
RPS23 ribosomal protein S23 -0.0535931
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0535632
RPL34 ribosomal protein L34 -0.0526119
RPS8 ribosomal protein S8 -0.050619
RPS24 ribosomal protein S24 -0.0505201
RPL35A ribosomal protein L35a -0.050019
PEG10 paternally expressed 10 -0.0485741
RPLP1 ribosomal protein, large, P1 -0.0476832
RPL31 ribosomal protein L31 -0.0435166
RPLP2 ribosomal protein, large, P2 -0.0412847
RPL23 ribosomal protein L23 -0.0399308
RPS19 ribosomal protein S19 -0.0385803
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0383037
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0376793
S100A9 S100 calcium binding protein A9 -0.0373076
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 -0.0372942
RPS11 ribosomal protein S11 -0.0369559
RPS14 ribosomal protein S14 -0.0365042
ACTG1 actin gamma 1 -0.0356107
FTL ferritin, light polypeptide -0.03492
KTN1 kinectin 1 (kinesin receptor) -0.0348508
HMGA1 high mobility group AT-hook 1 -0.0346127
RPL37 ribosomal protein L37 -0.0343191
MT2A metallothionein 2A -0.0339785
HMGA2 high mobility group AT-hook 2 -0.0329105
RPL12 ribosomal protein L12 -0.0324779
JMJD1C jumonji domain containing 1C -0.0324621
RPS25 ribosomal protein S25 -0.03202
TPT1 tumor protein, translationally-controlled 1 -0.0319555
RPS12 ribosomal protein S12 -0.0315222
RPS3 ribosomal protein S3 -0.0306776
RPS13 ribosomal protein S13 -0.0305648
RPL19 ribosomal protein L19 -0.0298785
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0296906
NAP1L1 nucleosome assembly protein 1-like 1 -0.0296428
RPL37A ribosomal protein L37a -0.0295633
ARIH1 ariadne RBR E3 ubiquitin protein ligase 1 -0.0295573
SOX4 SRY (sex determining region Y)-box 4 -0.0292779
HMGB1 high mobility group box 1 -0.0285706
RAB7A RAB7A, member RAS oncogene family -0.0279922
FBXO11 F-box protein 11 -0.0274099
CENPE centromere protein E, 312kDa -0.0271873
RACK1 receptor for activated C kinase 1 -0.0257293
RPL11 ribosomal protein L11 -0.025677
ANKHD1 ankyrin repeat and KH domain containing 1 -0.0255676
AFF4 AF4/FMR2 family, member 4 -0.0253745
ANKRD12 ankyrin repeat domain 12 -0.0252721
RPL26 ribosomal protein L26 -0.025265
RPL36 ribosomal protein L36 -0.0250654
RPL27A ribosomal protein L27a -0.0245512
TPM4 tropomyosin 4 -0.0243293
RPS10 ribosomal protein S10 -0.0242139
EGR1 early growth response 1 -0.024128
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.023964
RPS17 ribosomal protein S17 -0.0237076
RPL17-C18ORF32 RPL17-C18orf32 readthrough -0.0235076
CTBP2 C-terminal binding protein 2 -0.0231517
DEK DEK proto-oncogene -0.0228004
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.0227914
DSTN destrin (actin depolymerizing factor) -0.022492
CSNK1A1 casein kinase 1, alpha 1 -0.0224882
BBX bobby sox homolog (Drosophila) -0.0224763
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0224563
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0222702
RPS15 ribosomal protein S15 -0.0220637
RPS21 ribosomal protein S21 -0.0220415
EIF1 eukaryotic translation initiation factor 1 -0.0219257
RPL28 ribosomal protein L28 -0.0217989
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0217748
RPS5 ribosomal protein S5 -0.0217482
RPL32 ribosomal protein L32 -0.0216922
TPX2 TPX2, microtubule-associated -0.021152
RPL8 ribosomal protein L8 -0.0209353
RPL9 ribosomal protein L9 -0.0206814
CRY1 cryptochrome circadian clock 1 -0.0204113
CBX3 chromobox homolog 3 -0.0203726
RRBP1 ribosome binding protein 1 -0.0203223
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.020243
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.0202306
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0200726
LOC102724023 ES1 protein homolog, mitochondrial -0.0200634
IER3 immediate early response 3 -0.0199874
APLP2 amyloid beta (A4) precursor-like protein 2 -0.019986
PHIP pleckstrin homology domain interacting protein -0.0199594
SMC3 structural maintenance of chromosomes 3 -0.0199293
ENO1 enolase 1, (alpha) -0.0195973
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0195966
RPL5 ribosomal protein L5 -0.0195172
PFN1 profilin 1 -0.0194059
ZBTB20 zinc finger and BTB domain containing 20 -0.0191096
RPS29 ribosomal protein S29 -0.0190989