| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Balsalazide (sodium hydrate) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Balsalazide (sodium hydrate)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.0780493 |
| NCOA3 | nuclear receptor coactivator 3 | 0.074117 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0702605 |
| CEP250 | centrosomal protein 250kDa | 0.0598416 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0562629 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0530619 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.051679 |
| LASP1 | LIM and SH3 protein 1 | 0.0510112 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0487843 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0464902 |
| CDK12 | cyclin-dependent kinase 12 | 0.0424772 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0390323 |
| VCP | valosin containing protein | 0.0379335 |
| SMYD3 | SET and MYND domain containing 3 | 0.0378889 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.037502 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.03736 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0367567 |
| ENAH | enabled homolog (Drosophila) | 0.0360602 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0355427 |
| INTS6 | integrator complex subunit 6 | 0.0354592 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.035361 |
| MYOF | myoferlin | 0.0343865 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.0334552 |
| SP100 | SP100 nuclear antigen | 0.0333326 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0330687 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0329996 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.032208 |
| RAD51B | RAD51 paralog B | 0.031448 |
| PGK1 | phosphoglycerate kinase 1 | 0.0305651 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.030543 |
| AHNAK | AHNAK nucleoprotein | 0.0305118 |
| VEGFA | vascular endothelial growth factor A | 0.0299507 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0294986 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0294728 |
| FAM219A | family with sequence similarity 219, member A | 0.0285955 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0281558 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0281075 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0276736 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0272807 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0272376 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0271047 |
| EFNA5 | ephrin-A5 | 0.0270921 |
| MSI2 | musashi RNA-binding protein 2 | 0.0270157 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0269472 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0269455 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0268653 |
| FOXO3 | forkhead box O3 | 0.026634 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0266105 |
| KRT8 | keratin 8, type II | 0.026505 |
| PTK2 | protein tyrosine kinase 2 | 0.0264598 |
| PLEKHG4B | pleckstrin homology domain containing, family G (with RhoGef domain) member 4B | 0.0260742 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0259598 |
| NEBL | nebulette | 0.0258135 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0255997 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0253363 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.025191 |
| ENO1 | enolase 1, (alpha) | 0.0251685 |
| FAM168A | family with sequence similarity 168, member A | 0.0248041 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0247746 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | 0.0244523 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0244213 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0243972 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0242913 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0237844 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0233572 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.023321 |
| PLSCR1 | phospholipid scramblase 1 | 0.0232223 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.023203 |
| RNF213 | ring finger protein 213 | 0.0230224 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0230011 |
| KRT86 | keratin 86, type II | 0.0227755 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0224823 |
| KRT18 | keratin 18, type I | 0.0224556 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0223881 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0219867 |
| HELZ | helicase with zinc finger | 0.0213387 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0213227 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.021279 |
| NCOA6 | nuclear receptor coactivator 6 | 0.0209962 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 0.0209611 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0208367 |
| DENND1A | DENN/MADD domain containing 1A | 0.0206487 |
| KIAA1217 | KIAA1217 | 0.0206393 |
| PRELID2 | PRELI domain containing 2 | 0.0206195 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0205781 |
| CCNY | cyclin Y | 0.0203603 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0203099 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0200699 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0198484 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.019621 |
| NF1 | neurofibromin 1 | 0.0195936 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.019584 |
| ADAR | adenosine deaminase, RNA-specific | 0.0193904 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0193647 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0189774 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0187155 |
| MLPH | melanophilin | 0.0186468 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0186126 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0186041 |
| KIF1A | kinesin family member 1A | 0.0184804 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL19 | ribosomal protein L19 | -0.10637 |
| MT2A | metallothionein 2A | -0.0918007 |
| RPL23 | ribosomal protein L23 | -0.0715401 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0615746 |
| PTMA | prothymosin, alpha | -0.0578283 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0507468 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0499907 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0493103 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0434407 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0419002 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0407575 |
| S100A8 | S100 calcium binding protein A8 | -0.0403122 |
| B2M | beta-2-microglobulin | -0.038984 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0366758 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0355489 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0353266 |
| S100A9 | S100 calcium binding protein A9 | -0.0348708 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0334802 |
| TMSB10 | thymosin beta 10 | -0.0306387 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0301678 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.02826 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0278814 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0277041 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0257472 |
| RPL12 | ribosomal protein L12 | -0.025215 |
| RPS3 | ribosomal protein S3 | -0.0245788 |
| RPS8 | ribosomal protein S8 | -0.0244951 |
| TXNRD1 | thioredoxin reductase 1 | -0.0236449 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0235025 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0234965 |
| RPL9 | ribosomal protein L9 | -0.0233126 |
| CCNI | cyclin I | -0.02262 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0225044 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0224597 |
| FTL | ferritin, light polypeptide | -0.0223025 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.021765 |
| RPS2 | ribosomal protein S2 | -0.0217316 |
| CBX3 | chromobox homolog 3 | -0.0217313 |
| TMEM165 | transmembrane protein 165 | -0.0215839 |
| SET | SET nuclear proto-oncogene | -0.0212705 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0210609 |
| DSTN | destrin (actin depolymerizing factor) | -0.0207521 |
| RPL35A | ribosomal protein L35a | -0.0207161 |
| PRR11 | proline rich 11 | -0.0205584 |
| RPS19 | ribosomal protein S19 | -0.0204851 |
| STK17A | serine/threonine kinase 17a | -0.0203883 |
| S100A14 | S100 calcium binding protein A14 | -0.0198153 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0191323 |
| SERF2 | small EDRK-rich factor 2 | -0.018304 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0183026 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0181783 |
| PFDN4 | prefoldin subunit 4 | -0.0176339 |
| MUCL1 | mucin-like 1 | -0.0173744 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.0172704 |
| AREG | amphiregulin | -0.0172645 |
| MIEN1 | migration and invasion enhancer 1 | -0.0171964 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0170953 |
| COX6C | cytochrome c oxidase subunit VIc | -0.0168065 |
| RPS6 | ribosomal protein S6 | -0.0167249 |
| CENPF | centromere protein F, 350/400kDa | -0.0166598 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.016618 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.0163768 |
| CFB | complement factor B | -0.0162226 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0158811 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0158362 |
| RPL32 | ribosomal protein L32 | -0.0157971 |
| DUSP6 | dual specificity phosphatase 6 | -0.0157053 |
| OSMR | oncostatin M receptor | -0.0156827 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0156596 |
| YBX3 | Y box binding protein 3 | -0.0156254 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0153405 |
| KAZN | kazrin, periplakin interacting protein | -0.0152953 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0152738 |
| S100A7 | S100 calcium binding protein A7 | -0.0151311 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0150014 |
| PERP | PERP, TP53 apoptosis effector | -0.0149473 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0148061 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0147705 |
| S100A6 | S100 calcium binding protein A6 | -0.0147437 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0146894 |
| TMEM41B | transmembrane protein 41B | -0.0146474 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.0145738 |
| UBXN4 | UBX domain protein 4 | -0.0145699 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0141741 |
| RPS12 | ribosomal protein S12 | -0.0140646 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -0.0139573 |
| SPTSSA | serine palmitoyltransferase, small subunit A | -0.0137461 |
| RPS13 | ribosomal protein S13 | -0.0137367 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0136971 |
| SDC4 | syndecan 4 | -0.0136751 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0136508 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0136477 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0136287 |
| BCAS1 | breast carcinoma amplified sequence 1 | -0.0135429 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0134795 |
| WWOX | WW domain containing oxidoreductase | -0.0134438 |
| NDRG1 | N-myc downstream regulated 1 | -0.0132838 |
| SMIM14 | small integral membrane protein 14 | -0.0132082 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0131652 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | -0.0131224 |
