Balsalazide (sodium hydrate)_HCT15 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Balsalazide (sodium hydrate) perturbation in HCT15 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Balsalazide (sodium hydrate)_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0952401
AHNAK AHNAK nucleoprotein 0.0936363
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0810508
PRELID2 PRELI domain containing 2 0.0791683
PLEC plectin 0.0320057
MYH9 myosin, heavy chain 9, non-muscle 0.0312089
KIAA1217 KIAA1217 0.0305058
TXNRD1 thioredoxin reductase 1 0.0299602
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0296466
NEBL nebulette 0.0294575
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0282852
OGA O-GlcNAcase 0.0281641
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.0277049
EEF2 eukaryotic translation elongation factor 2 0.0257897
TMTC2 transmembrane and tetratricopeptide repeat containing 2 0.0250716
PARP4 poly (ADP-ribose) polymerase family, member 4 0.0249011
HELZ helicase with zinc finger 0.0247488
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0244999
FHIP1A FHF complex subunit HOOK interacting protein 1A 0.0241768
PRAG1 PEAK1 related, kinase-activating pseudokinase 1 0.0240985
ANXA2 annexin A2 0.0223119
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.0218713
BHLHE40 basic helix-loop-helix family, member e40 0.0218038
FHIT fragile histidine triad 0.0217148
SEC31A SEC31 homolog A (S. cerevisiae) 0.0214884
KLF5 Kruppel-like factor 5 (intestinal) 0.0214063
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0209519
RRM2 ribonucleotide reductase M2 0.0199042
TBC1D5 TBC1 domain family, member 5 0.0198221
ANKRD36 ankyrin repeat domain 36 0.0197316
METTL15 methyltransferase like 15 0.0193729
CEP192 centrosomal protein 192kDa 0.0191983
CEMIP2 cell migration inducing hyaluronidase 2 0.0190031
ZBTB20 zinc finger and BTB domain containing 20 0.0189835
IGF2R insulin-like growth factor 2 receptor 0.0189024
H1-4 H1.4 linker histone, cluster member 0.0187517
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.0183939
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0178343
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0173572
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.0172809
APLP2 amyloid beta (A4) precursor-like protein 2 0.0171992
ZNF654 zinc finger protein 654 0.0171613
SUMF1 sulfatase modifying factor 1 0.0171545
TBC1D22A TBC1 domain family, member 22A 0.017107
KRT8 keratin 8, type II 0.0169202
TAC4 tachykinin 4 (hemokinin) 0.0168459
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase 0.0167252
ADGRG6 adhesion G protein-coupled receptor G6 0.0165143
USP9Y ubiquitin specific peptidase 9, Y-linked 0.0163879
TPR translocated promoter region, nuclear basket protein 0.0162356
DMXL1 Dmx-like 1 0.0158495
TET2 tet methylcytosine dioxygenase 2 0.0156931
MACROD2 MACRO domain containing 2 0.0156627
KIAA1328 KIAA1328 0.0156023
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide 0.0155807
EXOC6B exocyst complex component 6B 0.0155685
CCNG2 cyclin G2 0.0154147
LOC112694756 uncharaterized LOC112694756 0.0154112
FLNA filamin A, alpha 0.0152819
BLTP1 bridge-like lipid transfer protein family member 1 0.0152118
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.0151507
KLF6 Kruppel-like factor 6 0.0151266
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.0150651
HSPA8 heat shock 70kDa protein 8 0.0146095
TIMP1 TIMP metallopeptidase inhibitor 1 0.0144788
YAP1 Yes-associated protein 1 0.0144638
NEK7 NIMA-related kinase 7 0.014463
CABIN1 calcineurin binding protein 1 0.0143008
RAB7A RAB7A, member RAS oncogene family 0.0142947
KDM4C lysine (K)-specific demethylase 4C 0.0142857
PTPRF protein tyrosine phosphatase, receptor type, F 0.0142626
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6 0.0142489
CKAP2 cytoskeleton associated protein 2 0.0141976
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0141794
XRN1 5'-3' exoribonuclease 1 0.0141575
ATRN attractin 0.0141257
ATG10 autophagy related 10 0.0140948
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0140699
ITPRID2 ITPR interacting domain containing 2 0.0140611
APOLD1 apolipoprotein L domain containing 1 0.0139249
MNMIP1 manchette microtubule inner protein 1 0.0138507
H1-0 H1.0 linker histone 0.0138496
POM121 POM121 transmembrane nucleoporin 0.013797
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 0.0137783
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 0.0137761
RAD51B RAD51 paralog B 0.013716
CELF2 CUGBP, Elav-like family member 2 0.0135286
NUP50 nucleoporin 50kDa 0.0135051
PRKCE protein kinase C, epsilon 0.0134427
CPNE1 copine I 0.0133637
MKI67 marker of proliferation Ki-67 0.0132997
RBBP7 retinoblastoma binding protein 7 0.0132896
DHX32 DEAH (Asp-Glu-Ala-His) box polypeptide 32 0.0132785
SMAD3 SMAD family member 3 0.013232
CDK8 cyclin-dependent kinase 8 0.0132176
ARF4 ADP-ribosylation factor 4 0.0131942
NCKAP1 NCK-associated protein 1 0.0131077
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0130397
EXOC1 exocyst complex component 1 0.0129359
ZNF106 zinc finger protein 106 0.0127962

decreased expression

Symbol Name Standardized Value
PTMA prothymosin, alpha -0.237879
RPS6 ribosomal protein S6 -0.130786
TMSB10 thymosin beta 10 -0.109127
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.108341
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0957444
RPS8 ribosomal protein S8 -0.0893467
TPT1 tumor protein, translationally-controlled 1 -0.0844172
RPL35A ribosomal protein L35a -0.0721559
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0703135
PKM pyruvate kinase, muscle -0.0648831
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.0632669
SCD stearoyl-CoA desaturase (delta-9-desaturase) -0.0624992
S100A9 S100 calcium binding protein A9 -0.0624151
ANKRD17 ankyrin repeat domain 17 -0.0605052
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.0603497
RPL18 ribosomal protein L18 -0.0572409
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0570109
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0567882
SET SET nuclear proto-oncogene -0.0511938
RPLP2 ribosomal protein, large, P2 -0.050733
RPL34 ribosomal protein L34 -0.0478005
RBPJ recombination signal binding protein for immunoglobulin kappa J region -0.0468494
PFN1 profilin 1 -0.0465699
RPLP1 ribosomal protein, large, P1 -0.0459588
RPS12 ribosomal protein S12 -0.0458455
RPS3 ribosomal protein S3 -0.0456783
DLG1 discs, large homolog 1 (Drosophila) -0.0455485
RPL8 ribosomal protein L8 -0.0453457
S100A6 S100 calcium binding protein A6 -0.0443682
NDRG1 N-myc downstream regulated 1 -0.0441442
KTN1 kinectin 1 (kinesin receptor) -0.0430145
SERBP1 SERPINE1 mRNA binding protein 1 -0.0429097
NAP1L1 nucleosome assembly protein 1-like 1 -0.0412262
RPS19 ribosomal protein S19 -0.0410431
CBX3 chromobox homolog 3 -0.040787
CADPS Ca++-dependent secretion activator -0.0407363
PNISR PNN-interacting serine/arginine-rich protein -0.0404455
KPNB1 karyopherin (importin) beta 1 -0.0404218
RPL11 ribosomal protein L11 -0.0392047
P4HB prolyl 4-hydroxylase, beta polypeptide -0.0389851
RPS23 ribosomal protein S23 -0.0389708
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0389263
CUX1 cut-like homeobox 1 -0.0387159
TPM4 tropomyosin 4 -0.0386424
RPS25 ribosomal protein S25 -0.0379028
RPS13 ribosomal protein S13 -0.0376906
RPL23 ribosomal protein L23 -0.0376731
EIF3A eukaryotic translation initiation factor 3, subunit A -0.0375731
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.0375219
RPL19 ribosomal protein L19 -0.0369082
EIF5B eukaryotic translation initiation factor 5B -0.03661
MT2A metallothionein 2A -0.0363108
RPL35 ribosomal protein L35 -0.0357253
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila) -0.0351546
RPL31 ribosomal protein L31 -0.0346811
SRPK2 SRSF protein kinase 2 -0.0346236
MSI2 musashi RNA-binding protein 2 -0.0344752
RPLP0 ribosomal protein, large, P0 -0.0344581
RPL9 ribosomal protein L9 -0.0335252
ACACA acetyl-CoA carboxylase alpha -0.0335066
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 -0.0330279
RPS11 ribosomal protein S11 -0.0329139
RPL26 ribosomal protein L26 -0.032857
CDK13 cyclin-dependent kinase 13 -0.0327908
RPS14 ribosomal protein S14 -0.0324639
RPL37A ribosomal protein L37a -0.032451
RPL36 ribosomal protein L36 -0.0324314
ZFHX3 zinc finger homeobox 3 -0.0322568
RBM25 RNA binding motif protein 25 -0.0322531
HMGA1 high mobility group AT-hook 1 -0.0322471
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -0.0322005
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.0314703
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -0.0313663
RPS5 ribosomal protein S5 -0.031185
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.0308603
RPS29 ribosomal protein S29 -0.0308405
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.0296713
RPS15 ribosomal protein S15 -0.0294573
RPS27A ribosomal protein S27a -0.0289545
GOLGA4 golgin A4 -0.0288495
PABPN1 poly(A) binding protein, nuclear 1 -0.0288317
GMDS GDP-mannose 4,6-dehydratase -0.0286929
RPL32 ribosomal protein L32 -0.0284927
RPL17-C18ORF32 RPL17-C18orf32 readthrough -0.0283529
PA2G4 proliferation-associated 2G4, 38kDa -0.0283427
CCND1 cyclin D1 -0.0280012
GARS1 glycyl-tRNA synthetase 1 -0.0276345
SCAF11 SR-related CTD-associated factor 11 -0.0275617
BAZ1B bromodomain adjacent to zinc finger domain, 1B -0.0275171
NOP58 NOP58 ribonucleoprotein -0.0274938
RPS16 ribosomal protein S16 -0.0274681
SETD5 SET domain containing 5 -0.0274139
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0273056
UBE2E2 ubiquitin-conjugating enzyme E2E 2 -0.0273011
ZFAND3 zinc finger, AN1-type domain 3 -0.0270095
UBE2K ubiquitin-conjugating enzyme E2K -0.0264219
RPS17 ribosomal protein S17 -0.0264091
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0263202
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) -0.0260134
S100A10 S100 calcium binding protein A10 -0.0256359