| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Balsalazide (sodium hydrate) perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Balsalazide (sodium hydrate)_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.266471 |
| FN1 | fibronectin 1 | 0.145328 |
| COL6A3 | collagen, type VI, alpha 3 | 0.113337 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0672262 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0605235 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0550207 |
| AHNAK | AHNAK nucleoprotein | 0.0549802 |
| ASPH | aspartate beta-hydroxylase | 0.0479179 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0457809 |
| COL1A1 | collagen, type I, alpha 1 | 0.037799 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0355343 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0345427 |
| PLEC | plectin | 0.0342231 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0322894 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.030577 |
| NAV2 | neuron navigator 2 | 0.02761 |
| ANXA2 | annexin A2 | 0.0261342 |
| SP100 | SP100 nuclear antigen | 0.0249376 |
| FAT1 | FAT atypical cadherin 1 | 0.0249156 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0248344 |
| ENO1 | enolase 1, (alpha) | 0.0233343 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0229259 |
| RIGI | RNA sensor RIG-I | 0.0222184 |
| PDLIM5 | PDZ and LIM domain 5 | 0.021698 |
| KIAA1217 | KIAA1217 | 0.0206534 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0206176 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0199596 |
| ANO6 | anoctamin 6 | 0.0197725 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0197464 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.018645 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0182881 |
| PRELID2 | PRELI domain containing 2 | 0.0177929 |
| FBN1 | fibrillin 1 | 0.0176501 |
| NAV1 | neuron navigator 1 | 0.0174634 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0173277 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0168712 |
| NRP1 | neuropilin 1 | 0.0168706 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0166595 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0166583 |
| RNF213 | ring finger protein 213 | 0.01618 |
| NAV3 | neuron navigator 3 | 0.0158483 |
| HDAC9 | histone deacetylase 9 | 0.0155424 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0155408 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0154277 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0144817 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0143949 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0139991 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0137228 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.013508 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0131759 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0131524 |
| RHOA | ras homolog family member A | 0.0130124 |
| CTSB | cathepsin B | 0.0128768 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0124893 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.012431 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0124211 |
| OSMR | oncostatin M receptor | 0.0123927 |
| HMGA2 | high mobility group AT-hook 2 | 0.0123747 |
| RHOC | ras homolog family member C | 0.0123214 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0123129 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0121519 |
| VEGFA | vascular endothelial growth factor A | 0.0121183 |
| EPHB1 | EPH receptor B1 | 0.0120943 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0119921 |
| GLIPR1 | GLI pathogenesis-related 1 | 0.0119216 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.011812 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0117528 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0117168 |
| ADAM12 | ADAM metallopeptidase domain 12 | 0.0116143 |
| VEGFC | vascular endothelial growth factor C | 0.0114712 |
| INTS6 | integrator complex subunit 6 | 0.0113943 |
| NREP | neuronal regeneration related protein | 0.0113805 |
| EMP1 | epithelial membrane protein 1 | 0.0112918 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0112573 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0112352 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0111692 |
| ARRDC3 | arrestin domain containing 3 | 0.01111 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0108953 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.0107103 |
| ATXN1 | ataxin 1 | 0.01064 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.010616 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0105094 |
| COL3A1 | collagen, type III, alpha 1 | 0.0105022 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0104551 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0104243 |
| SETBP1 | SET binding protein 1 | 0.01037 |
| PLSCR1 | phospholipid scramblase 1 | 0.0103488 |
| ANXA1 | annexin A1 | 0.0103136 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0102674 |
| RGS17 | regulator of G-protein signaling 17 | 0.0102136 |
| CD2AP | CD2-associated protein | 0.0100576 |
| FHIT | fragile histidine triad | 0.0100521 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0100505 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0100165 |
| RNF168 | ring finger protein 168, E3 ubiquitin protein ligase | 0.00993046 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.00987956 |
| COL22A1 | collagen, type XXII, alpha 1 | 0.009833 |
| JAG1 | jagged 1 | 0.00977624 |
| COL7A1 | collagen, type VII, alpha 1 | 0.00973829 |
| SDC2 | syndecan 2 | 0.00973357 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.190261 |
| MT2A | metallothionein 2A | -0.187158 |
| CADM1 | cell adhesion molecule 1 | -0.106243 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.096118 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0906346 |
| VIM | vimentin | -0.0686025 |
| B2M | beta-2-microglobulin | -0.0575723 |
| PTMA | prothymosin, alpha | -0.0546404 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.052443 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0468842 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0453883 |
| TMSB10 | thymosin beta 10 | -0.0448128 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0446494 |
| SPAG9 | sperm associated antigen 9 | -0.043433 |
| GOLGA4 | golgin A4 | -0.0427978 |
| STC1 | stanniocalcin 1 | -0.0418031 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0415479 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.04084 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0408285 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.040403 |
| IGFBP7 | insulin-like growth factor binding protein 7 | -0.0392708 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0389194 |
| CD44 | CD44 molecule (Indian blood group) | -0.0370556 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0369552 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0368058 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0367902 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0354897 |
| QKI | QKI, KH domain containing, RNA binding | -0.0351298 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0347064 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0329108 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0329005 |
| TRAM1 | translocation associated membrane protein 1 | -0.0327649 |
| TMEM165 | transmembrane protein 165 | -0.0325395 |
| RPS2 | ribosomal protein S2 | -0.0311371 |
| SEC24A | SEC24 family member A | -0.0309294 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0305082 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0302601 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0301506 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0298002 |
| CDH13 | cadherin 13 | -0.0296293 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0292825 |
| CALR | calreticulin | -0.0290769 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0290378 |
| RPS19 | ribosomal protein S19 | -0.0285014 |
| MTDH | metadherin | -0.0282804 |
| FTL | ferritin, light polypeptide | -0.02828 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0282658 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0279988 |
| MAP1B | microtubule-associated protein 1B | -0.027952 |
| MT1X | metallothionein 1X | -0.0277766 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0277115 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0269698 |
| RBM39 | RNA binding motif protein 39 | -0.0260978 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0260484 |
| SETD5 | SET domain containing 5 | -0.0260475 |
| ZNF292 | zinc finger protein 292 | -0.0256535 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0255844 |
| CLINT1 | clathrin interactor 1 | -0.0254702 |
| RPS8 | ribosomal protein S8 | -0.0249724 |
| RPLP2 | ribosomal protein, large, P2 | -0.0246882 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0246412 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0244482 |
| GOLGB1 | golgin B1 | -0.0242739 |
| KIF13A | kinesin family member 13A | -0.0241792 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0237997 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0237924 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0237114 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0236993 |
| EGFR | epidermal growth factor receptor | -0.0233455 |
| TMF1 | TATA element modulatory factor 1 | -0.0231057 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | -0.0231036 |
| GLG1 | golgi glycoprotein 1 | -0.0230375 |
| FBXO32 | F-box protein 32 | -0.0229036 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0228901 |
| TBC1D23 | TBC1 domain family, member 23 | -0.0226338 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0226163 |
| RPS12 | ribosomal protein S12 | -0.0225949 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0222669 |
| RPS6 | ribosomal protein S6 | -0.0221909 |
| SON | SON DNA binding protein | -0.0221619 |
| RPL5 | ribosomal protein L5 | -0.0220862 |
| DOCK5 | dedicator of cytokinesis 5 | -0.021916 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0216296 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0215236 |
| SEPTIN7 | septin 7 | -0.0215089 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0214392 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0213709 |
| PDE8A | phosphodiesterase 8A | -0.0213238 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0212757 |
| RTN4 | reticulon 4 | -0.0212746 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0212252 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0211529 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.020977 |
| COL1A2 | collagen, type I, alpha 2 | -0.0208921 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0208518 |
| SBF2 | SET binding factor 2 | -0.0208198 |
| BRD4 | bromodomain containing 4 | -0.0205512 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0200807 |
| RPL18 | ribosomal protein L18 | -0.0199721 |
| ACTN1 | actinin, alpha 1 | -0.0199187 |
