| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Balsalazide (sodium hydrate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Balsalazide (sodium hydrate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.22895 |
| SMAD3 | SMAD family member 3 | 0.123271 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.105488 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0916909 |
| TXNRD1 | thioredoxin reductase 1 | 0.0862817 |
| EZR | ezrin | 0.0815618 |
| NTN4 | netrin 4 | 0.0768929 |
| BCL2L1 | BCL2-like 1 | 0.0673949 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0667601 |
| PDZD8 | PDZ domain containing 8 | 0.0658758 |
| CTBP2 | C-terminal binding protein 2 | 0.0648318 |
| ARHGAP23 | Rho GTPase activating protein 23 | 0.0570182 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0558742 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0552737 |
| STK24 | serine/threonine kinase 24 | 0.0544402 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0537931 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0522012 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.049797 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0484247 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0473172 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.04663 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0459672 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0444226 |
| ATXN1 | ataxin 1 | 0.0429446 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0417789 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0402101 |
| MYO1E | myosin IE | 0.0401206 |
| FAT1 | FAT atypical cadherin 1 | 0.0397669 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0393243 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0385806 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0379932 |
| TJP1 | tight junction protein 1 | 0.0379697 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0378488 |
| FHL2 | four and a half LIM domains 2 | 0.0377987 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0375037 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0374313 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0371336 |
| WWC1 | WW and C2 domain containing 1 | 0.0369707 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0367535 |
| PDE10A | phosphodiesterase 10A | 0.036729 |
| LATS2 | large tumor suppressor kinase 2 | 0.0366575 |
| CCNYL1 | cyclin Y-like 1 | 0.036395 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0359178 |
| DST | dystonin | 0.0358452 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0354695 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0353384 |
| UTRN | utrophin | 0.0350711 |
| ANXA11 | annexin A11 | 0.0347349 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0346458 |
| VCL | vinculin | 0.0339897 |
| PPL | periplakin | 0.0339069 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0338089 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0332208 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0330027 |
| MYOF | myoferlin | 0.0326182 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | 0.0325497 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0321252 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0319934 |
| VEGFA | vascular endothelial growth factor A | 0.0314383 |
| FOXO1 | forkhead box O1 | 0.0310553 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0308839 |
| CLIC5 | chloride intracellular channel 5 | 0.0308563 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0307193 |
| MYEOV | myeloma overexpressed | 0.0299335 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0297987 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0297501 |
| PGCKA1 | PDCD10 and GCKIII kinases associated 1 | 0.0294553 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0288956 |
| SEPTIN9 | septin 9 | 0.0287249 |
| KRT18 | keratin 18, type I | 0.0285619 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0281921 |
| DIAPH1 | diaphanous-related formin 1 | 0.0278599 |
| PCBP2 | poly(rC) binding protein 2 | 0.0278525 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0275357 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0274863 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0271485 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0266855 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0263892 |
| SLTM | SAFB-like, transcription modulator | 0.026283 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0262056 |
| PRR5L | proline rich 5 like | 0.0260944 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0260218 |
| PUM2 | pumilio RNA-binding family member 2 | 0.025833 |
| YAP1 | Yes-associated protein 1 | 0.0257825 |
| RHEB | Ras homolog enriched in brain | 0.0256952 |
| EPS8L1 | EPS8-like 1 | 0.025639 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.0245411 |
| RPL3 | ribosomal protein L3 | 0.0243443 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0240537 |
| TES | testin LIM domain protein | 0.0240391 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0237789 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0236706 |
| TPM3 | tropomyosin 3 | 0.0231273 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0230203 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | 0.0228562 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0227888 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0226744 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.022324 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0222459 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0221712 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.160337 |
| NDRG1 | N-myc downstream regulated 1 | -0.129068 |
| MYH14 | myosin, heavy chain 14, non-muscle | -0.109738 |
| KRT20 | keratin 20, type I | -0.0983053 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0982912 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0963779 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0875313 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0875279 |
| LAMA4 | laminin, alpha 4 | -0.084022 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0826038 |
| DIAPH2 | diaphanous-related formin 2 | -0.0807331 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0793386 |
| FRY | furry homolog (Drosophila) | -0.0769521 |
| INTS6 | integrator complex subunit 6 | -0.0695457 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0685431 |
| EGR1 | early growth response 1 | -0.0657142 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0656049 |
| TMSB10 | thymosin beta 10 | -0.0655046 |
| AHNAK | AHNAK nucleoprotein | -0.0625983 |
| PTMA | prothymosin, alpha | -0.0589841 |
| PRELID2 | PRELI domain containing 2 | -0.058111 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0563672 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.056193 |
| PGK1 | phosphoglycerate kinase 1 | -0.0560839 |
| MCL1 | myeloid cell leukemia 1 | -0.0560349 |
| KRT19 | keratin 19, type I | -0.0554913 |
| SQSTM1 | sequestosome 1 | -0.0550132 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0549265 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.054342 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0535409 |
| AGR2 | anterior gradient 2 | -0.0521363 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0518033 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0516201 |
| ANXA2 | annexin A2 | -0.0494054 |
| JUN | jun proto-oncogene | -0.0491612 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0489899 |
| RPS24 | ribosomal protein S24 | -0.0484006 |
| RPS6 | ribosomal protein S6 | -0.0447526 |
| MMP7 | matrix metallopeptidase 7 | -0.0445987 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0431464 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0426948 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0426546 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0418358 |
| SDCBP | syndecan binding protein (syntenin) | -0.0411139 |
| LDHA | lactate dehydrogenase A | -0.0408682 |
| ASPH | aspartate beta-hydroxylase | -0.0398291 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0391531 |
| PCED1B | PC-esterase domain containing 1B | -0.0364898 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0362559 |
| ACTG1 | actin gamma 1 | -0.0346056 |
| EXOC4 | exocyst complex component 4 | -0.0343829 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0341026 |
| RPS3 | ribosomal protein S3 | -0.0339966 |
| RPS12 | ribosomal protein S12 | -0.0334033 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0330854 |
| KRT8 | keratin 8, type II | -0.0326584 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0324543 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0321822 |
| AEBP2 | AE binding protein 2 | -0.0321773 |
| RPL23 | ribosomal protein L23 | -0.0319103 |
| RPLP0 | ribosomal protein, large, P0 | -0.031834 |
| S100A10 | S100 calcium binding protein A10 | -0.0318137 |
| S100A6 | S100 calcium binding protein A6 | -0.0313636 |
| PRKCA | protein kinase C, alpha | -0.0308537 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0307584 |
| DGKH | diacylglycerol kinase, eta | -0.0306132 |
| TFRC | transferrin receptor | -0.0305173 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0304184 |
| GOLGB1 | golgin B1 | -0.0302128 |
| RPS8 | ribosomal protein S8 | -0.0299732 |
| POF1B | premature ovarian failure, 1B | -0.0296251 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0294049 |
| GSN | gelsolin | -0.029137 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0291221 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.029016 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0288643 |
| RRBP1 | ribosome binding protein 1 | -0.0285947 |
| FTL | ferritin, light polypeptide | -0.0284614 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0283102 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0280132 |
| KLF10 | Kruppel-like factor 10 | -0.0276369 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.027527 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0272967 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0271701 |
| SNX14 | sorting nexin 14 | -0.0268931 |
| B2M | beta-2-microglobulin | -0.0267131 |
| CCDC91 | coiled-coil domain containing 91 | -0.0267033 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0266515 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0262297 |
| RPL13A | ribosomal protein L13a | -0.0260197 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0258708 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0258219 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0257405 |
| WASF2 | WAS protein family, member 2 | -0.0255924 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0253874 |
| CAPN8 | calpain 8 | -0.0252234 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0250618 |
| RPL34 | ribosomal protein L34 | -0.025035 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0250146 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0249865 |