Balsalazide (sodium hydrate)_Hs 766T Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Balsalazide (sodium hydrate) perturbation in Hs 766T cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Balsalazide (sodium hydrate)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0745752
PDLIM5 PDZ and LIM domain 5 0.0736754
MBNL1 muscleblind-like splicing regulator 1 0.0665572
INTS6 integrator complex subunit 6 0.0642245
VCL vinculin 0.0602875
FOXO1 forkhead box O1 0.0549005
FNDC3B fibronectin type III domain containing 3B 0.0514412
DST dystonin 0.0505384
SMAD3 SMAD family member 3 0.0502961
MYH9 myosin, heavy chain 9, non-muscle 0.0474576
TRIO trio Rho guanine nucleotide exchange factor 0.0396195
DOCK5 dedicator of cytokinesis 5 0.0373131
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.0371162
MSN moesin 0.0368871
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.0344549
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.033595
PICALM phosphatidylinositol binding clathrin assembly protein 0.0331215
AOPEP aminopeptidase O (putative) 0.0327895
APLP2 amyloid beta (A4) precursor-like protein 2 0.0321266
RERE arginine-glutamic acid dipeptide (RE) repeats 0.0313103
MBNL2 muscleblind-like splicing regulator 2 0.0309528
CEMIP cell migration inducing protein, hyaluronan binding 0.0302697
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.0299895
ASXL1 additional sex combs like transcriptional regulator 1 0.0296095
MYOF myoferlin 0.0295929
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.0293497
CAPRIN2 caprin family member 2 0.0285868
BCAR3 breast cancer anti-estrogen resistance 3 0.0282792
HMGA2 high mobility group AT-hook 2 0.0280719
RASAL2 RAS protein activator like 2 0.0279941
PRELID2 PRELI domain containing 2 0.0270708
PLS3 plastin 3 0.0270047
PDE4D phosphodiesterase 4D, cAMP-specific 0.0263394
KLF5 Kruppel-like factor 5 (intestinal) 0.0263091
FN1 fibronectin 1 0.0258983
FLNA filamin A, alpha 0.0256197
MACF1 microtubule-actin crosslinking factor 1 0.0252459
CTBP2 C-terminal binding protein 2 0.0250031
PALM2AKAP2 PALM2 and AKAP2 fusion 0.024904
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.0242848
RALY RALY heterogeneous nuclear ribonucleoprotein 0.0242154
EFNA5 ephrin-A5 0.0236252
PLEC plectin 0.0233597
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.0227184
EXT1 exostosin glycosyltransferase 1 0.0224606
IQCJ-SCHIP1 IQCJ-SCHIP1 readthrough 0.0222993
VMP1 vacuole membrane protein 1 0.0215324
ASPH aspartate beta-hydroxylase 0.0214495
DDAH1 dimethylarginine dimethylaminohydrolase 1 0.0214149
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase 0.021254
ANKRD33B ankyrin repeat domain 33B 0.0206243
PLXNA2 plexin A2 0.0205672
NCEH1 neutral cholesterol ester hydrolase 1 0.0205578
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 0.0203372
LUZP1 leucine zipper protein 1 0.0195774
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0193463
ANO6 anoctamin 6 0.0191058
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.018861
PCBP2 poly(rC) binding protein 2 0.0187736
ZSWIM6 zinc finger, SWIM-type containing 6 0.0186178
SEPTIN9 septin 9 0.0183515
WWTR1 WW domain containing transcription regulator 1 0.0181157
CLIC4 chloride intracellular channel 4 0.0180738
CORO2A coronin, actin binding protein, 2A 0.0179943
PALLD palladin, cytoskeletal associated protein 0.0177599
CSMD2 CUB and Sushi multiple domains 2 0.0177508
SAMD4A sterile alpha motif domain containing 4A 0.0175219
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.017472
ACTN1 actinin, alpha 1 0.0172951
BHLHE40 basic helix-loop-helix family, member e40 0.0171008
AMOTL1 angiomotin like 1 0.0170126
ATXN1 ataxin 1 0.0169807
RPL3 ribosomal protein L3 0.0168704
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0165589
ASCC3 activating signal cointegrator 1 complex subunit 3 0.0163455
AFAP1L2 actin filament associated protein 1-like 2 0.0163007
SLCO1B3-SLCO1B7 SLCO1B3-SLCO1B7 readthrough 0.0162885
MTAP methylthioadenosine phosphorylase 0.016178
BRD2 bromodomain containing 2 0.0160976
BLCAP bladder cancer associated protein 0.0160417
EP300 E1A binding protein p300 0.0160137
FAT1 FAT atypical cadherin 1 0.0159327
WNK1 WNK lysine deficient protein kinase 1 0.0157779
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.0157335
TOM1L2 target of myb1-like 2 (chicken) 0.015642
CFLAR CASP8 and FADD-like apoptosis regulator 0.0155368
LAMA5 laminin, alpha 5 0.0154523
YAP1 Yes-associated protein 1 0.0152848
MEIS2 Meis homeobox 2 0.0152051
SETX senataxin 0.0151065
ECE1 endothelin converting enzyme 1 0.015067
EEF2 eukaryotic translation elongation factor 2 0.0148372
RND3 Rho family GTPase 3 0.0148273
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.0148176
PMM2 phosphomannomutase 2 0.0147673
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0147619
EGR1 early growth response 1 0.0147517
AGO2 argonaute RISC catalytic component 2 0.0146747
ARHGAP29 Rho GTPase activating protein 29 0.0144762
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 0.0144758

decreased expression

Symbol Name Standardized Value
TIMP3 TIMP metallopeptidase inhibitor 3 -0.31383
TPT1 tumor protein, translationally-controlled 1 -0.119895
TMSB4X thymosin beta 4, X-linked -0.0952196
NDRG1 N-myc downstream regulated 1 -0.0941846
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0920133
PTMA prothymosin, alpha -0.0884651
RPS6 ribosomal protein S6 -0.0834087
RPS21 ribosomal protein S21 -0.082509
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0802163
EMP1 epithelial membrane protein 1 -0.0786317
MTSS1 metastasis suppressor 1 -0.0774573
TMSB10 thymosin beta 10 -0.0741635
NAMPT nicotinamide phosphoribosyltransferase -0.0699255
PGK1 phosphoglycerate kinase 1 -0.0690534
B2M beta-2-microglobulin -0.0690178
MEF2A myocyte enhancer factor 2A -0.0630799
RPS8 ribosomal protein S8 -0.0614627
MT2A metallothionein 2A -0.0606839
S100A10 S100 calcium binding protein A10 -0.0582914
STC1 stanniocalcin 1 -0.057822
CLU clusterin -0.0573314
RPS13 ribosomal protein S13 -0.0533414
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0522127
RPS3 ribosomal protein S3 -0.0516471
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 -0.0497398
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta -0.0491813
ABI3BP ABI family, member 3 (NESH) binding protein -0.0490659
RPS24 ribosomal protein S24 -0.0481352
ALCAM activated leukocyte cell adhesion molecule -0.0479393
RPS25 ribosomal protein S25 -0.047309
HLA-B major histocompatibility complex, class I, B -0.0470967
RPLP2 ribosomal protein, large, P2 -0.046844
RPS19 ribosomal protein S19 -0.0461404
FLNB filamin B, beta -0.0460788
NAV2 neuron navigator 2 -0.0458079
GRB10 growth factor receptor-bound protein 10 -0.0457775
FTL ferritin, light polypeptide -0.0442943
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0441829
RPL23 ribosomal protein L23 -0.043931
S100A11 S100 calcium binding protein A11 -0.0414443
RPL12 ribosomal protein L12 -0.0414436
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0413297
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0410867
GOLGA4 golgin A4 -0.0406729
GNAS GNAS complex locus -0.0406013
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0405474
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0400634
RPLP0 ribosomal protein, large, P0 -0.0394227
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 -0.0391458
GARS1 glycyl-tRNA synthetase 1 -0.0388317
LDHA lactate dehydrogenase A -0.038784
RBM39 RNA binding motif protein 39 -0.0387254
RPL34 ribosomal protein L34 -0.0386239
RPLP1 ribosomal protein, large, P1 -0.0380774
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.038049
CAV1 caveolin 1, caveolae protein, 22kDa -0.0378888
RPL11 ribosomal protein L11 -0.0376757
S100A2 S100 calcium binding protein A2 -0.0375448
IFITM3 interferon induced transmembrane protein 3 -0.037531
DLG1 discs, large homolog 1 (Drosophila) -0.0374311
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) -0.0373988
IGF2 insulin-like growth factor 2 -0.0373455
RPL8 ribosomal protein L8 -0.0371147
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) -0.0365155
CANX calnexin -0.0365042
NAP1L1 nucleosome assembly protein 1-like 1 -0.0360581
SLC35F3 solute carrier family 35, member F3 -0.0354941
NPEPPS aminopeptidase puromycin sensitive -0.0351222
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -0.0349611
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 -0.0346427
RPL35A ribosomal protein L35a -0.0344257
S100A6 S100 calcium binding protein A6 -0.0343501
RPL26 ribosomal protein L26 -0.0342195
RPL37 ribosomal protein L37 -0.0338846
ENO1 enolase 1, (alpha) -0.0336923
RICTOR RPTOR independent companion of MTOR, complex 2 -0.0336245
MT1X metallothionein 1X -0.0326796
PRRC2C proline-rich coiled-coil 2C -0.0326705
CSTB cystatin B (stefin B) -0.0325704
RPS12 ribosomal protein S12 -0.0322844
MYO10 myosin X -0.0317446
PSD3 pleckstrin and Sec7 domain containing 3 -0.0314752
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.0314425
RPL27A ribosomal protein L27a -0.0309549
S100A9 S100 calcium binding protein A9 -0.030853
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa -0.0308116
AHNAK AHNAK nucleoprotein -0.0305918
CALB1 calbindin 1, 28kDa -0.0302888
TM4SF1 transmembrane 4 L six family member 1 -0.0300874
RPS14 ribosomal protein S14 -0.0298817
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0297544
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -0.0296799
FOSL1 FOS-like antigen 1 -0.0293614
HLA-E major histocompatibility complex, class I, E -0.0293388
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0293112
IFITM1 interferon induced transmembrane protein 1 -0.0292666
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.029262
ZMYND8 zinc finger, MYND-type containing 8 -0.0291992
IRF2BP2 interferon regulatory factor 2 binding protein 2 -0.0289737
EIF1 eukaryotic translation initiation factor 1 -0.028925