Balsalazide (sodium hydrate)_J82 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Balsalazide (sodium hydrate) perturbation in J82 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Balsalazide (sodium hydrate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0934414
TRIO trio Rho guanine nucleotide exchange factor 0.0573325
FNDC3B fibronectin type III domain containing 3B 0.0558394
MYH9 myosin, heavy chain 9, non-muscle 0.0539489
NAV2 neuron navigator 2 0.0518039
NALF1 NALCN channel auxiliary factor 1 0.0496042
PALM2AKAP2 PALM2 and AKAP2 fusion 0.047579
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0468096
FN1 fibronectin 1 0.0444314
COL5A1 collagen, type V, alpha 1 0.0439477
DST dystonin 0.0415551
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.0412074
FLNB filamin B, beta 0.0406455
CD44 CD44 molecule (Indian blood group) 0.0376138
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0348465
AHNAK AHNAK nucleoprotein 0.0329512
ADARB1 adenosine deaminase, RNA-specific, B1 0.0326775
ASPH aspartate beta-hydroxylase 0.0318684
EGFR epidermal growth factor receptor 0.0318184
KLF7 Kruppel-like factor 7 (ubiquitous) 0.0317763
GALNT18 polypeptide N-acetylgalactosaminyltransferase 18 0.0301093
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.030096
PRELID2 PRELI domain containing 2 0.0292492
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.0289292
ERBIN erbb2 interacting protein 0.0288471
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.0267586
ELL2 elongation factor, RNA polymerase II, 2 0.0265288
SMAD3 SMAD family member 3 0.0261803
DTNA dystrobrevin, alpha 0.0255114
SDK1 sidekick cell adhesion molecule 1 0.0245266
OSMR oncostatin M receptor 0.0241389
RBMS3 RNA binding motif, single stranded interacting protein 3 0.0241175
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.023591
LPP LIM domain containing preferred translocation partner in lipoma 0.0233578
ATXN1 ataxin 1 0.0231108
SEPTIN9 septin 9 0.0220379
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.0218966
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0208111
RUNX1 runt-related transcription factor 1 0.0203468
RAI14 retinoic acid induced 14 0.0202794
FARP1 FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) 0.0202219
NAV1 neuron navigator 1 0.0201829
SMYD3 SET and MYND domain containing 3 0.0198189
ANO6 anoctamin 6 0.0197633
RAD51B RAD51 paralog B 0.0195338
PHACTR1 phosphatase and actin regulator 1 0.0194642
IGFBP3 insulin-like growth factor binding protein 3 0.0193066
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.0192242
ANKRD36 ankyrin repeat domain 36 0.0190839
SAMD4A sterile alpha motif domain containing 4A 0.0189841
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.0189734
FAM219A family with sequence similarity 219, member A 0.0188456
FLNA filamin A, alpha 0.0188175
FHIT fragile histidine triad 0.0185602
FRMD6 FERM domain containing 6 0.0184749
PCLO piccolo presynaptic cytomatrix protein 0.0180584
DOCK5 dedicator of cytokinesis 5 0.0180313
PICALM phosphatidylinositol binding clathrin assembly protein 0.017817
IQCJ-SCHIP1 IQCJ-SCHIP1 readthrough 0.0177924
MACF1 microtubule-actin crosslinking factor 1 0.0174235
CRYBG3 beta-gamma crystallin domain containing 3 0.0173537
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0173016
HEG1 heart development protein with EGF-like domains 1 0.0171682
GSK3B glycogen synthase kinase 3 beta 0.016954
PTPN14 protein tyrosine phosphatase, non-receptor type 14 0.0167484
PDLIM5 PDZ and LIM domain 5 0.0164948
EFNA5 ephrin-A5 0.0164679
SLC12A8 solute carrier family 12, member 8 0.0161164
LIMCH1 LIM and calponin homology domains 1 0.0160078
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0159751
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0158895
PLSCR1 phospholipid scramblase 1 0.0158522
YEATS2 YEATS domain containing 2 0.0157211
MSN moesin 0.0156897
PBX3 pre-B-cell leukemia homeobox 3 0.0151933
PLEC plectin 0.0150787
CEP250 centrosomal protein 250kDa 0.0149592
VEGFC vascular endothelial growth factor C 0.0148907
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.0148372
SETX senataxin 0.0147385
UBA6 ubiquitin-like modifier activating enzyme 6 0.0145508
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.0145423
ZNF432 zinc finger protein 432 0.0144218
PODXL podocalyxin-like 0.0142892
COL7A1 collagen, type VII, alpha 1 0.014191
LRMDA leucine rich melanocyte differentiation associated 0.0140029
FER fer (fps/fes related) tyrosine kinase 0.013979
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.0138497
TNIK TRAF2 and NCK interacting kinase 0.0138338
KDM4C lysine (K)-specific demethylase 4C 0.0138058
TBC1D5 TBC1 domain family, member 5 0.013794
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1 0.0136647
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.0135632
JARID2 jumonji, AT rich interactive domain 2 0.0134876
FAT1 FAT atypical cadherin 1 0.0134304
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 0.0133792
NEK7 NIMA-related kinase 7 0.0133136
PTK2 protein tyrosine kinase 2 0.0132804
SIPA1L3 signal-induced proliferation-associated 1 like 3 0.0132143
EXT1 exostosin glycosyltransferase 1 0.0131907

decreased expression

Symbol Name Standardized Value
FTL ferritin, light polypeptide -0.24505
HLA-B major histocompatibility complex, class I, B -0.219986
MT2A metallothionein 2A -0.189513
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.180823
B2M beta-2-microglobulin -0.0998288
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0989506
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0863307
PTMA prothymosin, alpha -0.0855268
DEK DEK proto-oncogene -0.0847865
TMSB10 thymosin beta 10 -0.0813225
MARCKS myristoylated alanine-rich protein kinase C substrate -0.0804673
UGCG UDP-glucose ceramide glucosyltransferase -0.0725615
TPT1 tumor protein, translationally-controlled 1 -0.071173
MT1X metallothionein 1X -0.0706884
NDRG1 N-myc downstream regulated 1 -0.0656313
RPL35A ribosomal protein L35a -0.0636042
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0618757
RPS6 ribosomal protein S6 -0.061339
VIM vimentin -0.0584986
HLA-A major histocompatibility complex, class I, A -0.0576464
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0562177
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0550419
ADM adrenomedullin -0.0512384
FTH1 ferritin, heavy polypeptide 1 -0.0505555
RPLP2 ribosomal protein, large, P2 -0.0500322
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0494075
GNAS GNAS complex locus -0.0493491
RPL12 ribosomal protein L12 -0.0486057
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0469969
IFI6 interferon, alpha-inducible protein 6 -0.0449133
RPL23 ribosomal protein L23 -0.0419287
CTSD cathepsin D -0.0415145
CALR calreticulin -0.0414408
ACTG1 actin gamma 1 -0.040835
ENO1 enolase 1, (alpha) -0.0393178
S100A10 S100 calcium binding protein A10 -0.038961
TMSB4X thymosin beta 4, X-linked -0.0388637
BASP1 brain abundant, membrane attached signal protein 1 -0.038472
KPNB1 karyopherin (importin) beta 1 -0.0380356
RPS8 ribosomal protein S8 -0.0380215
GOLGA4 golgin A4 -0.0372082
ZFP36L1 ZFP36 ring finger protein-like 1 -0.0356765
RPS13 ribosomal protein S13 -0.0353656
NAP1L1 nucleosome assembly protein 1-like 1 -0.035193
RPL37 ribosomal protein L37 -0.0351084
EIF1 eukaryotic translation initiation factor 1 -0.0347041
IFITM3 interferon induced transmembrane protein 3 -0.0346443
PGK1 phosphoglycerate kinase 1 -0.0346439
RPL11 ribosomal protein L11 -0.0346382
S100A6 S100 calcium binding protein A6 -0.0343837
CAVIN1 caveolae associated protein 1 -0.0342904
PFN1 profilin 1 -0.0338104
HMGB1 high mobility group box 1 -0.0334313
LOC112694756 uncharaterized LOC112694756 -0.0332079
RPLP1 ribosomal protein, large, P1 -0.0329376
RPS3 ribosomal protein S3 -0.0327339
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.032108
SF3B2 splicing factor 3b, subunit 2, 145kDa -0.0319939
NOP58 NOP58 ribonucleoprotein -0.0310116
RAD21 RAD21 homolog (S. pombe) -0.030717
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0303883
HLA-E major histocompatibility complex, class I, E -0.0299841
RPL26 ribosomal protein L26 -0.0297591
MYL12B myosin, light chain 12B, regulatory -0.0292041
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0290185
WSB1 WD repeat and SOCS box containing 1 -0.0287127
RPS19 ribosomal protein S19 -0.0283219
RPL27A ribosomal protein L27a -0.0281818
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.0279599
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0278548
LDHA lactate dehydrogenase A -0.0278165
RPL34 ribosomal protein L34 -0.0277781
TPI1 triosephosphate isomerase 1 -0.0275094
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.027384
LMNA lamin A/C -0.0273015
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0270909
TXNRD1 thioredoxin reductase 1 -0.0268484
RBM39 RNA binding motif protein 39 -0.0268384
IER3 immediate early response 3 -0.0262323
RPL31 ribosomal protein L31 -0.02569
RPL32 ribosomal protein L32 -0.0256533
FAM162A family with sequence similarity 162, member A -0.025652
RPL19 ribosomal protein L19 -0.0251896
LMAN1 lectin, mannose-binding, 1 -0.0251354
AKAP12 A kinase (PRKA) anchor protein 12 -0.0250115
HMGB2 high mobility group box 2 -0.0248294
MORF4L2 mortality factor 4 like 2 -0.0248282
VDAC1 voltage-dependent anion channel 1 -0.0248027
ANKRD10 ankyrin repeat domain 10 -0.0247609
RPL8 ribosomal protein L8 -0.0247471
TUBB tubulin, beta class I -0.0245781
RPL35 ribosomal protein L35 -0.0245473
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 -0.0245081
RPS21 ribosomal protein S21 -0.0244707
RPS24 ribosomal protein S24 -0.0243203
SEPTIN7 septin 7 -0.0238684
RPL30 ribosomal protein L30 -0.0237243
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0235859
RPL5 ribosomal protein L5 -0.023479
TPM4 tropomyosin 4 -0.0230276