| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Balsalazide (sodium hydrate) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Balsalazide (sodium hydrate)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | 0.14468 |
| DST | dystonin | 0.0929049 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0912154 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0792114 |
| ENO1 | enolase 1, (alpha) | 0.0784805 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.068395 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0645178 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0638765 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0612754 |
| PTMA | prothymosin, alpha | 0.0561144 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0560101 |
| TXNIP | thioredoxin interacting protein | 0.0555219 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0541714 |
| RPS12 | ribosomal protein S12 | 0.052396 |
| PRELID2 | PRELI domain containing 2 | 0.0518199 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0477242 |
| CADM2 | cell adhesion molecule 2 | 0.0469262 |
| SLK | STE20-like kinase | 0.0449227 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.044419 |
| PCBP2 | poly(rC) binding protein 2 | 0.04402 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0436026 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0415915 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.041337 |
| VEGFA | vascular endothelial growth factor A | 0.0410407 |
| PCDH1 | protocadherin 1 | 0.0408277 |
| PLIN2 | perilipin 2 | 0.0400151 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0399957 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0398922 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0376885 |
| PKM | pyruvate kinase, muscle | 0.0376009 |
| FMNL2 | formin-like 2 | 0.0368519 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0353433 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0352427 |
| TPM3 | tropomyosin 3 | 0.0351411 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0337509 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0332087 |
| YEATS2 | YEATS domain containing 2 | 0.0330748 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0330392 |
| CAPRIN2 | caprin family member 2 | 0.0329619 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0329335 |
| MYOF | myoferlin | 0.0329291 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0324976 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0321534 |
| UBC | ubiquitin C | 0.0319063 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0317651 |
| HLA-A | major histocompatibility complex, class I, A | 0.0316399 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0314801 |
| RAD51B | RAD51 paralog B | 0.031474 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.030993 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0308185 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0305982 |
| RHOA | ras homolog family member A | 0.0303139 |
| DNER | delta/notch-like EGF repeat containing | 0.0300949 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0300847 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0299198 |
| RNF213 | ring finger protein 213 | 0.0297004 |
| TMSB4X | thymosin beta 4, X-linked | 0.0295153 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0294769 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0294638 |
| TPI1 | triosephosphate isomerase 1 | 0.0293221 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0292831 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0292689 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0287809 |
| FNIP1 | folliculin interacting protein 1 | 0.0285847 |
| ZNF292 | zinc finger protein 292 | 0.028302 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0282641 |
| MSN | moesin | 0.0280713 |
| SNX3 | sorting nexin 3 | 0.0273707 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0270878 |
| F2R | coagulation factor II (thrombin) receptor | 0.0268072 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.026788 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.0265602 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0263589 |
| ZNF148 | zinc finger protein 148 | 0.0262512 |
| TPRG1 | tumor protein p63 regulated 1 | 0.0261811 |
| RPL3 | ribosomal protein L3 | 0.0259834 |
| NDRG1 | N-myc downstream regulated 1 | 0.0258493 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0258232 |
| HELZ | helicase with zinc finger | 0.0257734 |
| EFNA5 | ephrin-A5 | 0.0257414 |
| SET | SET nuclear proto-oncogene | 0.0255357 |
| XPO1 | exportin 1 | 0.0254331 |
| CDK19 | cyclin-dependent kinase 19 | 0.0253411 |
| GOLGA4 | golgin A4 | 0.025168 |
| FAM162A | family with sequence similarity 162, member A | 0.0246577 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0239357 |
| B2M | beta-2-microglobulin | 0.02393 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0235719 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0233108 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0232632 |
| VPS35 | vacuolar protein sorting 35 homolog (S. cerevisiae) | 0.0229342 |
| CEP250 | centrosomal protein 250kDa | 0.0228034 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0227838 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0227549 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0226507 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0224808 |
| WASF2 | WAS protein family, member 2 | 0.022353 |
| ADAR | adenosine deaminase, RNA-specific | 0.022279 |
| RPL37A | ribosomal protein L37a | 0.022275 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0219586 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.280814 |
| TXNRD1 | thioredoxin reductase 1 | -0.155897 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.135531 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.116591 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.11338 |
| VIM | vimentin | -0.0752779 |
| ACTG1 | actin gamma 1 | -0.0662375 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0618052 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0594271 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0581726 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.052538 |
| AHNAK | AHNAK nucleoprotein | -0.0519255 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0517702 |
| TMSB10 | thymosin beta 10 | -0.0498434 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0443962 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0439338 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0438349 |
| USP34 | ubiquitin specific peptidase 34 | -0.0431611 |
| RGS4 | regulator of G-protein signaling 4 | -0.0426711 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.04173 |
| TMEM41B | transmembrane protein 41B | -0.0411801 |
| RIGI | RNA sensor RIG-I | -0.0403877 |
| JMJD1C | jumonji domain containing 1C | -0.0395891 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0376441 |
| CMIP | c-Maf inducing protein | -0.0375044 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0374492 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0373982 |
| EGR1 | early growth response 1 | -0.0372242 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0370129 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0369316 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.035359 |
| SRGN | serglycin | -0.0350919 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0350797 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0350413 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0349857 |
| TOP1 | topoisomerase (DNA) I | -0.0347212 |
| YBX3 | Y box binding protein 3 | -0.033292 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0330883 |
| FBXO11 | F-box protein 11 | -0.0325661 |
| EMP1 | epithelial membrane protein 1 | -0.0323696 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0321691 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0320721 |
| RAI1 | retinoic acid induced 1 | -0.0319728 |
| CENPF | centromere protein F, 350/400kDa | -0.0317756 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0314869 |
| SP100 | SP100 nuclear antigen | -0.0310331 |
| MT1X | metallothionein 1X | -0.0309036 |
| PLSCR1 | phospholipid scramblase 1 | -0.0306818 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0298761 |
| MT2A | metallothionein 2A | -0.0297577 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0296242 |
| NEK10 | NIMA-related kinase 10 | -0.0295036 |
| RTN4 | reticulon 4 | -0.0289258 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0288847 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0274709 |
| SGMS2 | sphingomyelin synthase 2 | -0.0274577 |
| KLF6 | Kruppel-like factor 6 | -0.0273165 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0272088 |
| RPL35A | ribosomal protein L35a | -0.0271077 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0268751 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0265795 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0264898 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0264678 |
| HPCAL1 | hippocalcin-like 1 | -0.0261267 |
| CD44 | CD44 molecule (Indian blood group) | -0.0259279 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0257103 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0256438 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | -0.0255353 |
| ERCC1 | excision repair cross-complementation group 1 | -0.0253701 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0253691 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0252312 |
| ARF1 | ADP-ribosylation factor 1 | -0.0251959 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0248011 |
| OSMR | oncostatin M receptor | -0.0247403 |
| HOMER1 | homer scaffolding protein 1 | -0.0241823 |
| KIF14 | kinesin family member 14 | -0.0241643 |
| RASAL2 | RAS protein activator like 2 | -0.0240091 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0239297 |
| S100A10 | S100 calcium binding protein A10 | -0.0235404 |
| INTS6 | integrator complex subunit 6 | -0.0230622 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0230022 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0229546 |
| MKI67 | marker of proliferation Ki-67 | -0.022798 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0226669 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0226301 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0226257 |
| WWTR1 | WW domain containing transcription regulator 1 | -0.0225846 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0221272 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | -0.0218907 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.021797 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0216883 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.021568 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0214966 |
| WDR26 | WD repeat domain 26 | -0.0211247 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.021069 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 | -0.0209239 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0208614 |
| PYGB | phosphorylase, glycogen; brain | -0.0207112 |
| ECT2 | epithelial cell transforming 2 | -0.0205286 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0205234 |