| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Balsalazide (sodium hydrate) perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Balsalazide (sodium hydrate)_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.176137 |
| PM20D1 | peptidase M20 domain containing 1 | 0.14406 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.116205 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0870443 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.075988 |
| GRAMD1B | GRAM domain containing 1B | 0.0721631 |
| POTEF | POTE ankyrin domain family, member F | 0.0717466 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0702159 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0681702 |
| MCL1 | myeloid cell leukemia 1 | 0.0628 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0531537 |
| COPA | coatomer protein complex, subunit alpha | 0.0509414 |
| TPM3 | tropomyosin 3 | 0.0498809 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0481903 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0467623 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0465669 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0430859 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0428191 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0423917 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0409055 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0385918 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0383705 |
| RPL3 | ribosomal protein L3 | 0.0382653 |
| BMP6 | bone morphogenetic protein 6 | 0.037227 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0347356 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0331091 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0324606 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0318974 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0296922 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0295218 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.0295089 |
| MSN | moesin | 0.0294067 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.028735 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0284789 |
| ATXN1 | ataxin 1 | 0.0272634 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0268164 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0261261 |
| PCBP2 | poly(rC) binding protein 2 | 0.0258331 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0248093 |
| UBC | ubiquitin C | 0.0247893 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0247494 |
| CALR | calreticulin | 0.0246036 |
| KLC1 | kinesin light chain 1 | 0.024437 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0238648 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0238403 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0237475 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0236395 |
| IL6 | interleukin 6 | 0.0235657 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0235485 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0232199 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0229149 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0225279 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0222504 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0221272 |
| ITGB5 | integrin, beta 5 | 0.0214851 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0214685 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0211156 |
| PDE10A | phosphodiesterase 10A | 0.021114 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0208008 |
| BRD2 | bromodomain containing 2 | 0.0202622 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0202482 |
| CASC3 | cancer susceptibility candidate 3 | 0.0200192 |
| LAMC2 | laminin, gamma 2 | 0.0199719 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0199018 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.019889 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0197749 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0197631 |
| TJP1 | tight junction protein 1 | 0.0196138 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0194721 |
| AXL | AXL receptor tyrosine kinase | 0.0192672 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0191302 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.019069 |
| LAMA5 | laminin, alpha 5 | 0.019008 |
| DIAPH1 | diaphanous-related formin 1 | 0.0185789 |
| MYO1E | myosin IE | 0.0185461 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.018467 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0184534 |
| SMAD4 | SMAD family member 4 | 0.0180212 |
| FLNA | filamin A, alpha | 0.0179524 |
| CCNY | cyclin Y | 0.0178758 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.017813 |
| MEF2D | myocyte enhancer factor 2D | 0.0178053 |
| VEGFA | vascular endothelial growth factor A | 0.0177348 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0176741 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0176592 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0175787 |
| YLPM1 | YLP motif containing 1 | 0.0175469 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.0175243 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0174869 |
| TCIM | transcriptional and immune response regulator | 0.0174661 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0173483 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0171972 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0170093 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0167261 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0167039 |
| CDCP1 | CUB domain containing protein 1 | 0.0166432 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0165795 |
| CCNL1 | cyclin L1 | 0.0165264 |
| CLIC4 | chloride intracellular channel 4 | 0.0164222 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0164031 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.239804 |
| VIM | vimentin | -0.182181 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.177748 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.171605 |
| TXNRD1 | thioredoxin reductase 1 | -0.152731 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.138507 |
| FTL | ferritin, light polypeptide | -0.118763 |
| TMSB10 | thymosin beta 10 | -0.117237 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0838608 |
| IER3 | immediate early response 3 | -0.0827063 |
| ACTG1 | actin gamma 1 | -0.072841 |
| IGF2 | insulin-like growth factor 2 | -0.0719709 |
| CAVIN1 | caveolae associated protein 1 | -0.0695519 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.068099 |
| BICC1 | BicC family RNA binding protein 1 | -0.0676126 |
| PTMA | prothymosin, alpha | -0.0628974 |
| HDAC9 | histone deacetylase 9 | -0.0565913 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0519539 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0514467 |
| RPL19 | ribosomal protein L19 | -0.0472948 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0472943 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0453613 |
| S100A6 | S100 calcium binding protein A6 | -0.0436808 |
| RPL35A | ribosomal protein L35a | -0.0434923 |
| RPS21 | ribosomal protein S21 | -0.0425095 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0416115 |
| NRG1 | neuregulin 1 | -0.0407092 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0393587 |
| AK1 | adenylate kinase 1 | -0.0390417 |
| ASPH | aspartate beta-hydroxylase | -0.0385748 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0378541 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0365273 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0361501 |
| LMNA | lamin A/C | -0.0354607 |
| HMGA1 | high mobility group AT-hook 1 | -0.0346185 |
| SRGN | serglycin | -0.0332548 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0330958 |
| S100A10 | S100 calcium binding protein A10 | -0.0330518 |
| RPS24 | ribosomal protein S24 | -0.0328954 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0321801 |
| RPL23 | ribosomal protein L23 | -0.0320085 |
| ERBIN | erbb2 interacting protein | -0.0320004 |
| ACACA | acetyl-CoA carboxylase alpha | -0.031676 |
| RPS8 | ribosomal protein S8 | -0.0311114 |
| GNAS | GNAS complex locus | -0.0309895 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0305626 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0305469 |
| RPLP1 | ribosomal protein, large, P1 | -0.0304888 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0300844 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0296509 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0296121 |
| RPL34 | ribosomal protein L34 | -0.0294104 |
| RPS29 | ribosomal protein S29 | -0.0293559 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0293546 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0291956 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0291721 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0291119 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0290783 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0289628 |
| RPL11 | ribosomal protein L11 | -0.0288621 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0287448 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0286855 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0286281 |
| CYRIB | CYFIP related Rac1 interactor B | -0.0278675 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0278357 |
| SERF2 | small EDRK-rich factor 2 | -0.0278318 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.027753 |
| STC1 | stanniocalcin 1 | -0.0276556 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0271738 |
| ZFHX3 | zinc finger homeobox 3 | -0.0270399 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0267766 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.0267252 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0267052 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0265484 |
| TMEM123 | transmembrane protein 123 | -0.0264671 |
| SEPTIN7 | septin 7 | -0.0264481 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0264392 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0264004 |
| EFNA5 | ephrin-A5 | -0.0263174 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0262844 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0261426 |
| DST | dystonin | -0.0260975 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0257923 |
| WDR43 | WD repeat domain 43 | -0.0255766 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0254599 |
| SQSTM1 | sequestosome 1 | -0.0254586 |
| SMAD2 | SMAD family member 2 | -0.0253881 |
| RPS19 | ribosomal protein S19 | -0.0252973 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0248242 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0246716 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0244201 |
| RPL31 | ribosomal protein L31 | -0.0243118 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0242213 |
| RPL8 | ribosomal protein L8 | -0.0242104 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0240653 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0238452 |
| RPL36 | ribosomal protein L36 | -0.0237104 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0235564 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0234864 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0234593 |
