| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Balsalazide (sodium hydrate) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Balsalazide (sodium hydrate)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0857338 |
| LAMC2 | laminin, gamma 2 | 0.0665216 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0622322 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0525312 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0511032 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0484771 |
| OGA | O-GlcNAcase | 0.0456565 |
| MT2A | metallothionein 2A | 0.0435462 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0419684 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0417684 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0407173 |
| NAV2 | neuron navigator 2 | 0.0402711 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0402037 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0388659 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0387955 |
| RUNX1 | runt-related transcription factor 1 | 0.0386092 |
| CDCP1 | CUB domain containing protein 1 | 0.0384539 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0378503 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.037848 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0371339 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0369574 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0363412 |
| AK1 | adenylate kinase 1 | 0.0354929 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0351875 |
| ASPH | aspartate beta-hydroxylase | 0.0342292 |
| VCL | vinculin | 0.0328946 |
| PRKCA | protein kinase C, alpha | 0.0319738 |
| OSMR | oncostatin M receptor | 0.0319624 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0317897 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | 0.030844 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0307065 |
| INTS6 | integrator complex subunit 6 | 0.0303505 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0298122 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0297238 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0294764 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | 0.0294245 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0291664 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.029079 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0288449 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.028547 |
| ENO1 | enolase 1, (alpha) | 0.0284224 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0281792 |
| FNIP1 | folliculin interacting protein 1 | 0.0277839 |
| AHNAK | AHNAK nucleoprotein | 0.027225 |
| APP | amyloid beta (A4) precursor protein | 0.0271705 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0268417 |
| GOLGA3 | golgin A3 | 0.0267003 |
| FLNB | filamin B, beta | 0.0264977 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0258232 |
| USP53 | ubiquitin specific peptidase 53 | 0.0257637 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0257037 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0254631 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0253087 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0252872 |
| METTL15 | methyltransferase like 15 | 0.0251985 |
| HDAC4 | histone deacetylase 4 | 0.0248253 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0247907 |
| SEPTIN10 | septin 10 | 0.0247656 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.024717 |
| GPATCH2L | G patch domain containing 2-like | 0.0245409 |
| CNKSR3 | CNKSR family member 3 | 0.0242584 |
| PFKP | phosphofructokinase, platelet | 0.0240951 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.02388 |
| STC1 | stanniocalcin 1 | 0.0238697 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0237662 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0237114 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0235656 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0235022 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0234521 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0232335 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.023189 |
| GRAMD1B | GRAM domain containing 1B | 0.023144 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0231347 |
| CD44 | CD44 molecule (Indian blood group) | 0.0230456 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0230448 |
| PLEC | plectin | 0.0230328 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0229933 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0229682 |
| CALU | calumenin | 0.0228229 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0226495 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | 0.0225849 |
| PPP2R2C | protein phosphatase 2, regulatory subunit B, gamma | 0.0225489 |
| CDH13 | cadherin 13 | 0.0225447 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0223475 |
| LOXL2 | lysyl oxidase-like 2 | 0.0223383 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0221676 |
| ATG7 | autophagy related 7 | 0.0221277 |
| ADM | adrenomedullin | 0.0220173 |
| EGFR | epidermal growth factor receptor | 0.0219679 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0219639 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0215313 |
| UBC | ubiquitin C | 0.0214362 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0214253 |
| FERMT2 | fermitin family member 2 | 0.0213696 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0211861 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0211144 |
| SFTPA2 | surfactant protein A2 | 0.021095 |
| SUB1 | SUB1 homolog (S. cerevisiae) | 0.0210807 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0210427 |
| MSN | moesin | 0.020829 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GRB10 | growth factor receptor-bound protein 10 | -0.104227 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0877564 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.079834 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0731554 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0675376 |
| TXNRD1 | thioredoxin reductase 1 | -0.0597047 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0589464 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0588023 |
| RIOK3 | RIO kinase 3 | -0.0573037 |
| ATOSA | atos homolog A | -0.0566693 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0550641 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0501918 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | -0.0476811 |
| EGR1 | early growth response 1 | -0.045903 |
| FDPS | farnesyl diphosphate synthase | -0.0420212 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0416099 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0412442 |
| B2M | beta-2-microglobulin | -0.0399681 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.039592 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0382356 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0380831 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0377175 |
| SVIL | supervillin | -0.0373909 |
| TLK1 | tousled-like kinase 1 | -0.0373119 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0368921 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.036831 |
| CMIP | c-Maf inducing protein | -0.03678 |
| RPS6 | ribosomal protein S6 | -0.0366849 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0362619 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.036042 |
| SETD5 | SET domain containing 5 | -0.036001 |
| ZNF638 | zinc finger protein 638 | -0.0351057 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.0347877 |
| TAOK3 | TAO kinase 3 | -0.0345331 |
| SRPK2 | SRSF protein kinase 2 | -0.0340667 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | -0.0331362 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0323908 |
| RPL23 | ribosomal protein L23 | -0.0323457 |
| REPS1 | RALBP1 associated Eps domain containing 1 | -0.0320818 |
| LMO7 | LIM domain 7 | -0.0320356 |
| PDE8A | phosphodiesterase 8A | -0.0319557 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0319158 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0315557 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0314189 |
| FTL | ferritin, light polypeptide | -0.0313415 |
| S100A8 | S100 calcium binding protein A8 | -0.0312551 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0312246 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0309521 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0309517 |
| RIGI | RNA sensor RIG-I | -0.0307233 |
| MUC16 | mucin 16, cell surface associated | -0.0306846 |
| GRB7 | growth factor receptor-bound protein 7 | -0.0306729 |
| FN1 | fibronectin 1 | -0.029742 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0296032 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0291759 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0291559 |
| DSG2 | desmoglein 2 | -0.0289597 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0287912 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0287522 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0286897 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0285704 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0285316 |
| FBXO34 | F-box protein 34 | -0.0282497 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0280507 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0278656 |
| PTEN | phosphatase and tensin homolog | -0.0276785 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | -0.0276681 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0273914 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0272899 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0270598 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | -0.0263821 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0263057 |
| CPNE8 | copine VIII | -0.0261641 |
| CD2AP | CD2-associated protein | -0.0261113 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0257985 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.02574 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.025555 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0254748 |
| FBXO32 | F-box protein 32 | -0.0253064 |
| WDR26 | WD repeat domain 26 | -0.0251596 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0250703 |
| MYO1E | myosin IE | -0.0250093 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0249302 |
| RPS25 | ribosomal protein S25 | -0.0248032 |
| SNX9 | sorting nexin 9 | -0.0246713 |
| S100P | S100 calcium binding protein P | -0.0244931 |
| ERBIN | erbb2 interacting protein | -0.0242693 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0242245 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0240661 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0239733 |
| PMM2 | phosphomannomutase 2 | -0.0239498 |
| DYNC2I1 | dynein 2 intermediate chain 1 | -0.0238263 |
| NUP58 | nucleoporin 58 | -0.0237966 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0237072 |
| USP15 | ubiquitin specific peptidase 15 | -0.0236373 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0235973 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0234867 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.023214 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0231175 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0225936 |
