| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Balsalazide (sodium hydrate) perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Balsalazide (sodium hydrate)_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.147216 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.114825 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.101153 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0976205 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0838554 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0821962 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0712174 |
| COPA | coatomer protein complex, subunit alpha | 0.0708005 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.070572 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0680242 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0616235 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.060478 |
| PRELID2 | PRELI domain containing 2 | 0.0556295 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0509741 |
| OGA | O-GlcNAcase | 0.0509601 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0471385 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0434697 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0415154 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0388807 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0385015 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0371385 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0369606 |
| PCBP2 | poly(rC) binding protein 2 | 0.0369535 |
| FAM168A | family with sequence similarity 168, member A | 0.0364008 |
| TLN1 | talin 1 | 0.0360202 |
| ENO1 | enolase 1, (alpha) | 0.0357166 |
| GRAMD1B | GRAM domain containing 1B | 0.0353606 |
| PRKCE | protein kinase C, epsilon | 0.0345829 |
| GOLGB1 | golgin B1 | 0.0341499 |
| CANX | calnexin | 0.0334302 |
| ATP11A | ATPase, class VI, type 11A | 0.0333814 |
| PHF21A | PHD finger protein 21A | 0.0333614 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0327301 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0327238 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0325362 |
| PGK1 | phosphoglycerate kinase 1 | 0.032081 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0320248 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0310063 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0306633 |
| UBC | ubiquitin C | 0.0300208 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0297841 |
| TPM3 | tropomyosin 3 | 0.0295362 |
| PYGL | phosphorylase, glycogen, liver | 0.0294366 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0291993 |
| CALR | calreticulin | 0.0290616 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0290211 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0289906 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0287497 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0287398 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0286206 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0284945 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0283864 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0282884 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0281935 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0281344 |
| MCL1 | myeloid cell leukemia 1 | 0.0278626 |
| PREPL | prolyl endopeptidase-like | 0.0278265 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0275091 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0274844 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0274082 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0273727 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0273294 |
| GOLGA4 | golgin A4 | 0.0271463 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0267621 |
| FMNL2 | formin-like 2 | 0.0267188 |
| PDE10A | phosphodiesterase 10A | 0.0264959 |
| HELZ | helicase with zinc finger | 0.0264237 |
| PLEC | plectin | 0.0262149 |
| FAM13A | family with sequence similarity 13, member A | 0.0261398 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0261318 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0259458 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0257934 |
| ADAR | adenosine deaminase, RNA-specific | 0.0257038 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0249946 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0246882 |
| RSF1 | remodeling and spacing factor 1 | 0.0245169 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0241418 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0241291 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0239715 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0237666 |
| WWOX | WW domain containing oxidoreductase | 0.0235121 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0234358 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0233739 |
| KRT18 | keratin 18, type I | 0.0231309 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0230367 |
| XPO1 | exportin 1 | 0.0229607 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0228813 |
| PKM | pyruvate kinase, muscle | 0.0224787 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.022463 |
| LATS2 | large tumor suppressor kinase 2 | 0.022436 |
| H1-0 | H1.0 linker histone | 0.0220864 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0220226 |
| BBX | bobby sox homolog (Drosophila) | 0.0218675 |
| JAK1 | Janus kinase 1 | 0.0218588 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0217391 |
| PRPF8 | pre-mRNA processing factor 8 | 0.021453 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0213909 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0213563 |
| SSH2 | slingshot protein phosphatase 2 | 0.0213504 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0211886 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TFPI2 | tissue factor pathway inhibitor 2 | -0.135736 |
| VIM | vimentin | -0.0815844 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0713373 |
| TMSB10 | thymosin beta 10 | -0.0697794 |
| YBX3 | Y box binding protein 3 | -0.0663032 |
| PTMA | prothymosin, alpha | -0.0650934 |
| TXNRD1 | thioredoxin reductase 1 | -0.0545442 |
| EGR1 | early growth response 1 | -0.0507507 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0452273 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0440172 |
| MT2A | metallothionein 2A | -0.0433938 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0429024 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0394369 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0394316 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0393918 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0390869 |
| NABP1 | nucleic acid binding protein 1 | -0.0388074 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0372688 |
| CENPF | centromere protein F, 350/400kDa | -0.0360792 |
| HMGA2 | high mobility group AT-hook 2 | -0.035223 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0349222 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0340694 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0332608 |
| RPL23 | ribosomal protein L23 | -0.0325623 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0323928 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0321616 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0318905 |
| KLF6 | Kruppel-like factor 6 | -0.0307862 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0304913 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0304743 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0299403 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0298256 |
| HLA-B | major histocompatibility complex, class I, B | -0.0296596 |
| RPL9 | ribosomal protein L9 | -0.0291765 |
| RPL35A | ribosomal protein L35a | -0.0288732 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0287268 |
| RPL26 | ribosomal protein L26 | -0.0285561 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.028373 |
| MYL12B | myosin, light chain 12B, regulatory | -0.027872 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0275626 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0274341 |
| PMP22 | peripheral myelin protein 22 | -0.0272887 |
| TUBA1C | tubulin, alpha 1c | -0.0266776 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0263662 |
| IER3 | immediate early response 3 | -0.0259987 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0250912 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0245367 |
| VCL | vinculin | -0.0245167 |
| RPS8 | ribosomal protein S8 | -0.0243385 |
| RIGI | RNA sensor RIG-I | -0.0241034 |
| RPS6 | ribosomal protein S6 | -0.0235567 |
| TUBA1B | tubulin, alpha 1b | -0.0233102 |
| CBX3 | chromobox homolog 3 | -0.0229153 |
| RPL12 | ribosomal protein L12 | -0.0227922 |
| RPS24 | ribosomal protein S24 | -0.0227677 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0225588 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0221842 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0221514 |
| OSMR | oncostatin M receptor | -0.0219646 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0219033 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.021835 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0213837 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0213609 |
| CENPE | centromere protein E, 312kDa | -0.0210507 |
| THADA | thyroid adenoma associated | -0.020936 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0207932 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0201715 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0199638 |
| PLSCR1 | phospholipid scramblase 1 | -0.0197856 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0193148 |
| DOCK3 | dedicator of cytokinesis 3 | -0.0191367 |
| CDK17 | cyclin-dependent kinase 17 | -0.0188633 |
| RPL19 | ribosomal protein L19 | -0.0188487 |
| RPL11 | ribosomal protein L11 | -0.0186676 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.0183571 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0181963 |
| RASAL2 | RAS protein activator like 2 | -0.0179908 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0179427 |
| AFG2A | AFG2 AAA ATPase homolog A | -0.0178038 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0177628 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0173492 |
| RPS21 | ribosomal protein S21 | -0.0172785 |
| MT1X | metallothionein 1X | -0.0171841 |
| RRM2 | ribonucleotide reductase M2 | -0.0171627 |
| RPL34 | ribosomal protein L34 | -0.0171007 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0170783 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0169963 |
| TPI1 | triosephosphate isomerase 1 | -0.0169396 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0168473 |
| RPS19 | ribosomal protein S19 | -0.0167084 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0166321 |
| RPLP0 | ribosomal protein, large, P0 | -0.0164807 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0164395 |
| FHL2 | four and a half LIM domains 2 | -0.0163959 |
| MIDN | midnolin | -0.0163199 |
| STC1 | stanniocalcin 1 | -0.0163058 |
| S100A6 | S100 calcium binding protein A6 | -0.0161914 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0161687 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0161647 |
| HMGA1 | high mobility group AT-hook 1 | -0.0160504 |
