| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Balsalazide (sodium hydrate) perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Balsalazide (sodium hydrate)_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PM20D1 | peptidase M20 domain containing 1 | 0.18153 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.152101 |
| PDE10A | phosphodiesterase 10A | 0.125204 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.10649 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0974713 |
| GRAMD1B | GRAM domain containing 1B | 0.0864842 |
| FTL | ferritin, light polypeptide | 0.0750431 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0730285 |
| DST | dystonin | 0.0694009 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.0598245 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0558265 |
| MYOF | myoferlin | 0.0555807 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0555691 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.0550661 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0534269 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0464858 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0437475 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0411793 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0397798 |
| MT2A | metallothionein 2A | 0.0396325 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0392554 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0342138 |
| TXNRD1 | thioredoxin reductase 1 | 0.0337397 |
| PDE7B | phosphodiesterase 7B | 0.0317183 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.031641 |
| KYNU | kynureninase | 0.0308202 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0303079 |
| SLF1 | SMC5-SMC6 complex localization factor 1 | 0.0288464 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | 0.0281596 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0275024 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.026893 |
| PRELID2 | PRELI domain containing 2 | 0.0263568 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0262643 |
| BDNF | brain-derived neurotrophic factor | 0.0256013 |
| NRCAM | neuronal cell adhesion molecule | 0.0255524 |
| CENPF | centromere protein F, 350/400kDa | 0.0250593 |
| ITPK1 | inositol-tetrakisphosphate 1-kinase | 0.0249447 |
| EGR1 | early growth response 1 | 0.0248323 |
| EPHA4 | EPH receptor A4 | 0.0245137 |
| RBM39 | RNA binding motif protein 39 | 0.0244152 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0241995 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0241774 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0241448 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0241013 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0237782 |
| MKI67 | marker of proliferation Ki-67 | 0.0235857 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0233831 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0227921 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0224906 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0224372 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0224068 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0223142 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0221752 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0221088 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0214245 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 0.0213887 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0210589 |
| TENM2 | teneurin transmembrane protein 2 | 0.0202656 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0200184 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.019672 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0196349 |
| SPAG9 | sperm associated antigen 9 | 0.0194028 |
| MAFK | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K | 0.0192855 |
| CDK6 | cyclin-dependent kinase 6 | 0.0188322 |
| NHSL1 | NHS-like 1 | 0.0187496 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0185805 |
| ARF1 | ADP-ribosylation factor 1 | 0.0182925 |
| CEP72 | centrosomal protein 72kDa | 0.0182792 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0181378 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0179181 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0178583 |
| MALT1 | MALT1 paracaspase | 0.0177102 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0174951 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.017418 |
| TBXT | T-box transcription factor T | 0.0172974 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0171717 |
| ATXN1 | ataxin 1 | 0.017159 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | 0.0170524 |
| NEK7 | NIMA-related kinase 7 | 0.0170521 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0167126 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0161608 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0161195 |
| RPL35A | ribosomal protein L35a | 0.0160178 |
| FAM13A | family with sequence similarity 13, member A | 0.0160037 |
| RIGI | RNA sensor RIG-I | 0.0157654 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.015505 |
| RGS2 | regulator of G-protein signaling 2 | 0.0154357 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | 0.0152944 |
| DIAPH3 | diaphanous-related formin 3 | 0.0151755 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.015099 |
| GSG1L2 | GSG1 like 2 | 0.014931 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0149128 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0147337 |
| PRKD3 | protein kinase D3 | 0.014691 |
| CD109 | CD109 molecule | 0.0146448 |
| EFNA5 | ephrin-A5 | 0.0145025 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.0142573 |
| ALPK2 | alpha-kinase 2 | 0.0142346 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0141271 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.014115 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.23285 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.224608 |
| VIM | vimentin | -0.2042 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.172124 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.150803 |
| UBC | ubiquitin C | -0.144125 |
| RPS27A | ribosomal protein S27a | -0.121603 |
| PTMA | prothymosin, alpha | -0.111626 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.101868 |
| CANX | calnexin | -0.093887 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0828548 |
| MCL1 | myeloid cell leukemia 1 | -0.0807103 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0802018 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0779118 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0777611 |
| ENO1 | enolase 1, (alpha) | -0.0771892 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0761131 |
| ASPH | aspartate beta-hydroxylase | -0.0745871 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.069056 |
| AUTS2 | autism susceptibility candidate 2 | -0.0681123 |
| CDH13 | cadherin 13 | -0.0675746 |
| RPS12 | ribosomal protein S12 | -0.0649943 |
| S100A6 | S100 calcium binding protein A6 | -0.0577256 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0559525 |
| RPS24 | ribosomal protein S24 | -0.0548238 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0504122 |
| LDHA | lactate dehydrogenase A | -0.0501149 |
| TMSB10 | thymosin beta 10 | -0.0498137 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0484905 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0464736 |
| SET | SET nuclear proto-oncogene | -0.0464241 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.045667 |
| RPS3 | ribosomal protein S3 | -0.043904 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0436859 |
| AHNAK | AHNAK nucleoprotein | -0.0433396 |
| STC1 | stanniocalcin 1 | -0.0433262 |
| RPL26 | ribosomal protein L26 | -0.0431276 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0419029 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0415142 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0397676 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0394903 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0384606 |
| RPS8 | ribosomal protein S8 | -0.038127 |
| RPL37A | ribosomal protein L37a | -0.0379248 |
| CD44 | CD44 molecule (Indian blood group) | -0.0372525 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0358582 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0350367 |
| CTSL | cathepsin L | -0.034351 |
| RPL36A | ribosomal protein L36a | -0.034092 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0335861 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0325112 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0323663 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0323294 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0320619 |
| APP | amyloid beta (A4) precursor protein | -0.0316039 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0315603 |
| NCKAP5 | NCK-associated protein 5 | -0.0305525 |
| RACK1 | receptor for activated C kinase 1 | -0.0302661 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0301888 |
| RANBP17 | RAN binding protein 17 | -0.0295049 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.029399 |
| SQSTM1 | sequestosome 1 | -0.029306 |
| CALR | calreticulin | -0.0292881 |
| RPL9 | ribosomal protein L9 | -0.0292402 |
| LAMB1 | laminin, beta 1 | -0.0286645 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0284219 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.028075 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0277856 |
| SOX6 | SRY (sex determining region Y)-box 6 | -0.0275591 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0274888 |
| VCL | vinculin | -0.0270692 |
| CUX1 | cut-like homeobox 1 | -0.0270501 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0269096 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0268108 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0267649 |
| RPL23 | ribosomal protein L23 | -0.0262969 |
| DENND1A | DENN/MADD domain containing 1A | -0.02625 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0262314 |
| RPL31 | ribosomal protein L31 | -0.0261621 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | -0.0260933 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0260476 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0260043 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0257966 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0257317 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0256444 |
| FMNL2 | formin-like 2 | -0.0255665 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0254607 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0253978 |
| TPM4 | tropomyosin 4 | -0.0252334 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0250646 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0249695 |
| RPL15 | ribosomal protein L15 | -0.0245652 |
| HLA-A | major histocompatibility complex, class I, A | -0.024481 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0242367 |
| PCBP2 | poly(rC) binding protein 2 | -0.0240859 |
| TPM3 | tropomyosin 3 | -0.0240055 |
| PCBP3 | poly(rC) binding protein 3 | -0.0239498 |
| B2M | beta-2-microglobulin | -0.0236015 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0227712 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0227702 |
