| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Balsalazide (sodium hydrate) perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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199 genes differentially expressed following the Balsalazide (sodium hydrate)_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | 0.238596 |
| DSCAM | Down syndrome cell adhesion molecule | 0.134177 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.125289 |
| SQSTM1 | sequestosome 1 | 0.122527 |
| RORA | RAR-related orphan receptor A | 0.116244 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.099945 |
| LMO7 | LIM domain 7 | 0.0849669 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0848757 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0761274 |
| ERBIN | erbb2 interacting protein | 0.0742481 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0730213 |
| RPS12 | ribosomal protein S12 | 0.0725145 |
| INTS6 | integrator complex subunit 6 | 0.0691625 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0670397 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0667274 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0624145 |
| EZR | ezrin | 0.0606611 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0566931 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0556786 |
| PDE10A | phosphodiesterase 10A | 0.0542896 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | 0.0542144 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0536935 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0526194 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0520169 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0509947 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0502222 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0484911 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0482456 |
| ZNF292 | zinc finger protein 292 | 0.0481875 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0477865 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0471778 |
| PHF3 | PHD finger protein 3 | 0.0465426 |
| GNAS | GNAS complex locus | 0.0458 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0447671 |
| MAP1B | microtubule-associated protein 1B | 0.0435111 |
| PKM | pyruvate kinase, muscle | 0.0417671 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0399994 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.039045 |
| MYO5B | myosin VB | 0.0389126 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0385908 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0382157 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0374279 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0371264 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0370357 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0358299 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0356863 |
| EFNA5 | ephrin-A5 | 0.0353982 |
| FOXP1 | forkhead box P1 | 0.0351473 |
| ANXA2 | annexin A2 | 0.0330941 |
| MYO1D | myosin ID | 0.0314237 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0307159 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0306461 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0304958 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0304721 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0301933 |
| ANO6 | anoctamin 6 | 0.0299918 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.029659 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0290174 |
| USP34 | ubiquitin specific peptidase 34 | 0.0281885 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0281306 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0279595 |
| RPS8 | ribosomal protein S8 | 0.0274512 |
| RAD51B | RAD51 paralog B | 0.0268282 |
| ZNF638 | zinc finger protein 638 | 0.0266316 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0257991 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0257551 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.025688 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0252451 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0250977 |
| RUNX1 | runt-related transcription factor 1 | 0.0244637 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.024373 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0241685 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0224176 |
| RAB2A | RAB2A, member RAS oncogene family | 0.022115 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0214893 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0203428 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0203329 |
| OGA | O-GlcNAcase | 0.0202832 |
| EGFR | epidermal growth factor receptor | 0.0201148 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0197998 |
| PRELID2 | PRELI domain containing 2 | 0.0190815 |
| NAV1 | neuron navigator 1 | 0.0189248 |
| POTEF | POTE ankyrin domain family, member F | 0.0183272 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0149252 |
| FMNL2 | formin-like 2 | 0.0147468 |
| FLNB | filamin B, beta | 0.0138908 |
| PRKCA | protein kinase C, alpha | 0.0133563 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0124441 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0123145 |
| NABP1 | nucleic acid binding protein 1 | 0.0115133 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0103906 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.00849915 |
| MCL1 | myeloid cell leukemia 1 | 0.00847195 |
| SBF2 | SET binding factor 2 | 0.00809973 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.00802052 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.00769807 |
| ATP13A3 | ATPase type 13A3 | 0.00704388 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.00682122 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.00630138 |
| VCL | vinculin | 0.0062288 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.314308 |
| FN1 | fibronectin 1 | -0.224257 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.213918 |
| TMSB10 | thymosin beta 10 | -0.122061 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0930149 |
| B2M | beta-2-microglobulin | -0.0877204 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0857106 |
| NDRG1 | N-myc downstream regulated 1 | -0.0848289 |
| IGF2 | insulin-like growth factor 2 | -0.0804275 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0771088 |
| MMP1 | matrix metallopeptidase 1 | -0.0755904 |
| GPC6 | glypican 6 | -0.0734179 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0683659 |
| PTK2 | protein tyrosine kinase 2 | -0.0663233 |
| PTMA | prothymosin, alpha | -0.0661737 |
| JMJD1C | jumonji domain containing 1C | -0.0658951 |
| RNF213 | ring finger protein 213 | -0.0640108 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0607354 |
| RPL23 | ribosomal protein L23 | -0.0593857 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0590426 |
| LAMB3 | laminin, beta 3 | -0.058426 |
| CCNI | cyclin I | -0.0568333 |
| GOLGA4 | golgin A4 | -0.0554453 |
| LDHA | lactate dehydrogenase A | -0.0547101 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0545822 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0545753 |
| BPTF | bromodomain PHD finger transcription factor | -0.0533063 |
| HELZ | helicase with zinc finger | -0.0523333 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0520375 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0519211 |
| PARD3 | par-3 family cell polarity regulator | -0.049396 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.049097 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0489447 |
| NF1 | neurofibromin 1 | -0.0484497 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0470536 |
| INHBA | inhibin, beta A | -0.0462358 |
| ASPH | aspartate beta-hydroxylase | -0.0453835 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0451981 |
| CDH13 | cadherin 13 | -0.0439759 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0438831 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0428423 |
| CLTC | clathrin, heavy chain (Hc) | -0.0421899 |
| DST | dystonin | -0.041326 |
| RPS6 | ribosomal protein S6 | -0.0396751 |
| FAM13A | family with sequence similarity 13, member A | -0.0393785 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0376719 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0374756 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0349225 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0337722 |
| CANX | calnexin | -0.033624 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0313802 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0305162 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0304829 |
| PDLIM5 | PDZ and LIM domain 5 | -0.029917 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0290505 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0279639 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0279554 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0268156 |
| TPM4 | tropomyosin 4 | -0.0264634 |
| MED13 | mediator complex subunit 13 | -0.0262318 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0259597 |
| HMGA2 | high mobility group AT-hook 2 | -0.0258634 |
| RPL35A | ribosomal protein L35a | -0.0257189 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0251456 |
| FTL | ferritin, light polypeptide | -0.0246243 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0243963 |
| CD44 | CD44 molecule (Indian blood group) | -0.0239842 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.023871 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0231173 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0228961 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0228912 |
| MYO10 | myosin X | -0.0222913 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0211734 |
| VMP1 | vacuole membrane protein 1 | -0.0202345 |
| RPL37A | ribosomal protein L37a | -0.0195419 |
| NAV2 | neuron navigator 2 | -0.0191558 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0174789 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0163927 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.015735 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0155765 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0124051 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0119512 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0113543 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0102379 |
| YAP1 | Yes-associated protein 1 | -0.0102024 |
| RRBP1 | ribosome binding protein 1 | -0.00872332 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.00791571 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.00788968 |
| RIGI | RNA sensor RIG-I | -0.00688686 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.00582962 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0058256 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.00450057 |
| MT2A | metallothionein 2A | -0.00401736 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0039919 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.00361805 |
| CNKSR3 | CNKSR family member 3 | -0.00287616 |
| MYO1E | myosin IE | -0.00214828 |
| METTL15 | methyltransferase like 15 | -0.00162285 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -1.23601E-4 |
