| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Balsalazide (sodium hydrate) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Balsalazide (sodium hydrate)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.101196 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0971319 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0914186 |
| NTM | neurotrimin | 0.0888918 |
| HDAC9 | histone deacetylase 9 | 0.0846721 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0811404 |
| NPAS3 | neuronal PAS domain protein 3 | 0.0724494 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0698899 |
| LRRC4C | leucine rich repeat containing 4C | 0.0693111 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0624457 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0606828 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0588067 |
| UBC | ubiquitin C | 0.0584292 |
| MED13L | mediator complex subunit 13-like | 0.0520567 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | 0.0509861 |
| PRELID2 | PRELI domain containing 2 | 0.0504469 |
| RCOR1 | REST corepressor 1 | 0.0497006 |
| DST | dystonin | 0.0484893 |
| ANK2 | ankyrin 2, neuronal | 0.0483675 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0458551 |
| KCTD16 | potassium channel tetramerization domain containing 16 | 0.0449035 |
| TJP1 | tight junction protein 1 | 0.0437853 |
| RAD51B | RAD51 paralog B | 0.0428103 |
| GPC3 | glypican 3 | 0.0423529 |
| CDH19 | cadherin 19, type 2 | 0.0407799 |
| DMD | dystrophin | 0.0406849 |
| PTK2 | protein tyrosine kinase 2 | 0.0405661 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | 0.0393353 |
| AHNAK | AHNAK nucleoprotein | 0.0393007 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0392965 |
| INTS6 | integrator complex subunit 6 | 0.038215 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0378224 |
| NHSL1 | NHS-like 1 | 0.037729 |
| PHIP | pleckstrin homology domain interacting protein | 0.0372017 |
| ATXN2 | ataxin 2 | 0.0366587 |
| TOX | thymocyte selection-associated high mobility group box | 0.0365553 |
| UTRN | utrophin | 0.0348387 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.034341 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0341603 |
| FAM171B | family with sequence similarity 171, member B | 0.0333359 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0332505 |
| OLA1 | Obg-like ATPase 1 | 0.0332212 |
| RASAL2 | RAS protein activator like 2 | 0.0325476 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.032357 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0313725 |
| ATXN1 | ataxin 1 | 0.0310811 |
| PHF21A | PHD finger protein 21A | 0.031061 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0309931 |
| GLI3 | GLI family zinc finger 3 | 0.0309443 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.030842 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0306227 |
| FOXO1 | forkhead box O1 | 0.0304439 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0303604 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0303338 |
| GAB2 | GRB2-associated binding protein 2 | 0.0303061 |
| PHF3 | PHD finger protein 3 | 0.0302629 |
| CLIC4 | chloride intracellular channel 4 | 0.030243 |
| PLS3 | plastin 3 | 0.0298254 |
| STAU1 | staufen double-stranded RNA binding protein 1 | 0.0297624 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0294495 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0291179 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0289846 |
| RBM20 | RNA binding motif protein 20 | 0.0288748 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0287061 |
| TMSB10 | thymosin beta 10 | 0.0284125 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0283485 |
| FOXP2 | forkhead box P2 | 0.0283034 |
| PALLD | palladin, cytoskeletal associated protein | 0.028136 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | 0.0277563 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0277444 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0277189 |
| BRMS1L | breast cancer metastasis-suppressor 1-like | 0.0276797 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0276716 |
| TNRC6B | trinucleotide repeat containing 6B | 0.0271907 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0270366 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0269057 |
| JUN | jun proto-oncogene | 0.0267788 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0267263 |
| EMP1 | epithelial membrane protein 1 | 0.0266076 |
| GSE1 | Gse1 coiled-coil protein | 0.0265572 |
| DPYD | dihydropyrimidine dehydrogenase | 0.026555 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0257825 |
| SMYD3 | SET and MYND domain containing 3 | 0.0253874 |
| AARS1 | alanyl-tRNA synthetase 1 | 0.0253349 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0253058 |
| RNF216 | ring finger protein 216 | 0.0253005 |
| PCDH7 | protocadherin 7 | 0.025244 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0252308 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0252163 |
| ZFAND6 | zinc finger, AN1-type domain 6 | 0.0248596 |
| NFIA | nuclear factor I/A | 0.0248027 |
| NCOA2 | nuclear receptor coactivator 2 | 0.024782 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0247444 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0244868 |
| COL3A1 | collagen, type III, alpha 1 | 0.0241083 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0237701 |
| EP300 | E1A binding protein p300 | 0.0236088 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0235823 |
| DNAH14 | dynein, axonemal, heavy chain 14 | 0.023468 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0233855 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.11844 |
| RPS6 | ribosomal protein S6 | -0.09619 |
| CENPF | centromere protein F, 350/400kDa | -0.0882051 |
| RPS2 | ribosomal protein S2 | -0.078543 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0758775 |
| PEG10 | paternally expressed 10 | -0.0739071 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0718765 |
| SFRP4 | secreted frizzled-related protein 4 | -0.0714217 |
| MKI67 | marker of proliferation Ki-67 | -0.0701514 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0692703 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0668561 |
| PTMA | prothymosin, alpha | -0.0644196 |
| TMSB4X | thymosin beta 4, X-linked | -0.0638064 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0632371 |
| SOX2 | SRY (sex determining region Y)-box 2 | -0.0630395 |
| COL11A1 | collagen, type XI, alpha 1 | -0.0613737 |
| POTEF | POTE ankyrin domain family, member F | -0.0593785 |
| RPS12 | ribosomal protein S12 | -0.0586062 |
| SNX6 | sorting nexin 6 | -0.0583064 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0510698 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0505084 |
| ACTG1 | actin gamma 1 | -0.0499765 |
| METAP2 | methionyl aminopeptidase 2 | -0.0471128 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0466262 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0465224 |
| RPS16 | ribosomal protein S16 | -0.0464755 |
| CFL2 | cofilin 2 (muscle) | -0.0459502 |
| GOLGA4 | golgin A4 | -0.0450819 |
| ANXA1 | annexin A1 | -0.0449028 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0434753 |
| H1-4 | H1.4 linker histone, cluster member | -0.042653 |
| RPL11 | ribosomal protein L11 | -0.041031 |
| ITGAV | integrin, alpha V | -0.0410024 |
| COL1A2 | collagen, type I, alpha 2 | -0.0400362 |
| RPL37 | ribosomal protein L37 | -0.0399162 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0397748 |
| ZFR | zinc finger RNA binding protein | -0.0396722 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0388757 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0387012 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0378223 |
| MAP4 | microtubule-associated protein 4 | -0.0365557 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.035986 |
| NOP58 | NOP58 ribonucleoprotein | -0.0355218 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | -0.0349425 |
| PFN1 | profilin 1 | -0.0338616 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0335954 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0327878 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0324469 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0323095 |
| SRPK2 | SRSF protein kinase 2 | -0.0323011 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.032126 |
| DSTN | destrin (actin depolymerizing factor) | -0.0317548 |
| WASL | Wiskott-Aldrich syndrome-like | -0.0317269 |
| IPO7 | importin 7 | -0.0316068 |
| MLEC | malectin | -0.0312437 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | -0.0308793 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.030567 |
| URI1 | URI1, prefoldin-like chaperone | -0.0303545 |
| TPM3 | tropomyosin 3 | -0.0302971 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0302537 |
| POU3F2 | POU class 3 homeobox 2 | -0.0297774 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0296508 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0291079 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0290991 |
| GNAS | GNAS complex locus | -0.0287737 |
| PDS5A | PDS5 cohesin associated factor A | -0.028654 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.028557 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | -0.0284744 |
| CLTC | clathrin, heavy chain (Hc) | -0.028385 |
| FBL | fibrillarin | -0.0282734 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.0280954 |
| NUP98 | nucleoporin 98kDa | -0.027837 |
| CENPE | centromere protein E, 312kDa | -0.0276839 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | -0.0276662 |
| KIF4A | kinesin family member 4A | -0.0275607 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.027378 |
| ANXA5 | annexin A5 | -0.0273329 |
| RPLP0 | ribosomal protein, large, P0 | -0.0273186 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.027314 |
| YBX1 | Y box binding protein 1 | -0.0272999 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -0.0272466 |
| CLASP2 | cytoplasmic linker associated protein 2 | -0.0269734 |
| SUPT16H | suppressor of Ty 16 homolog (S. cerevisiae) | -0.0269533 |
| RPS8 | ribosomal protein S8 | -0.0267806 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0263907 |
| RBM25 | RNA binding motif protein 25 | -0.0263188 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0262477 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0261265 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0260813 |
| RPS25 | ribosomal protein S25 | -0.0259725 |
| RPL7 | ribosomal protein L7 | -0.0257036 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0256166 |
| VMP1 | vacuole membrane protein 1 | -0.0255048 |
| SSH2 | slingshot protein phosphatase 2 | -0.0254984 |
| MATR3 | matrin 3 | -0.0254001 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0252664 |
| RFPL4B | ret finger protein-like 4B | -0.025222 |
| CCNA2 | cyclin A2 | -0.0251787 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | -0.0250651 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0249363 |
