| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Balsalazide (sodium hydrate) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Balsalazide (sodium hydrate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZFP36 | ZFP36 ring finger protein | 0.172339 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.139116 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.120087 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0827789 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.0807147 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0776866 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0698712 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0694837 |
| SEPTIN9 | septin 9 | 0.0693095 |
| SFTPA2 | surfactant protein A2 | 0.0692476 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0688545 |
| VEGFA | vascular endothelial growth factor A | 0.0684044 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0680266 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0638887 |
| PCBP2 | poly(rC) binding protein 2 | 0.0632882 |
| FNDC3B | fibronectin type III domain containing 3B | 0.061331 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0589803 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.056884 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.056331 |
| MSN | moesin | 0.0537215 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0531287 |
| PKM | pyruvate kinase, muscle | 0.0510221 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0503764 |
| FBL | fibrillarin | 0.048473 |
| BRD2 | bromodomain containing 2 | 0.0480648 |
| RPL3 | ribosomal protein L3 | 0.0474958 |
| SAMD4B | sterile alpha motif domain containing 4B | 0.0470158 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0454628 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0452827 |
| NAV2 | neuron navigator 2 | 0.044847 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0447206 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0444569 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0440819 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0439497 |
| CTBP2 | C-terminal binding protein 2 | 0.043385 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0430262 |
| POTEF | POTE ankyrin domain family, member F | 0.0421607 |
| TPM3 | tropomyosin 3 | 0.0402504 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0396907 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0390929 |
| LDHA | lactate dehydrogenase A | 0.038917 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0388791 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0385113 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0375462 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0369821 |
| PTK2 | protein tyrosine kinase 2 | 0.0366647 |
| ANO6 | anoctamin 6 | 0.0364992 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0362605 |
| L1CAM | L1 cell adhesion molecule | 0.0361358 |
| UBC | ubiquitin C | 0.0357762 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0351735 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.034849 |
| FMNL2 | formin-like 2 | 0.0344445 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0344232 |
| YBX1 | Y box binding protein 1 | 0.0339016 |
| INTS6 | integrator complex subunit 6 | 0.0337797 |
| ADM | adrenomedullin | 0.0331384 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0330462 |
| MAP1B | microtubule-associated protein 1B | 0.0324375 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.030498 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0304595 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0302616 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0302361 |
| NOTCH2 | notch 2 | 0.0298511 |
| ZNF638 | zinc finger protein 638 | 0.0297876 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0291083 |
| SMAD3 | SMAD family member 3 | 0.0289172 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0282655 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0282173 |
| RPS12 | ribosomal protein S12 | 0.0279025 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0278922 |
| RHOA | ras homolog family member A | 0.0278342 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0276081 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0275017 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0274355 |
| YAP1 | Yes-associated protein 1 | 0.0273825 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0269506 |
| PLEC | plectin | 0.0268354 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0267532 |
| HYOU1 | hypoxia up-regulated 1 | 0.0265546 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0263212 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0261562 |
| ARRDC3 | arrestin domain containing 3 | 0.0256317 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0256115 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0255852 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0254907 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0254575 |
| FAT1 | FAT atypical cadherin 1 | 0.0254014 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 0.025378 |
| ENO1 | enolase 1, (alpha) | 0.0252735 |
| ERBIN | erbb2 interacting protein | 0.0251599 |
| FLNB | filamin B, beta | 0.0249101 |
| DENND5A | DENN/MADD domain containing 5A | 0.0248182 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0247977 |
| STC2 | stanniocalcin 2 | 0.0246134 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0242844 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.024262 |
| RPL4 | ribosomal protein L4 | 0.0242235 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0241899 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0235855 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.126529 |
| CD44 | CD44 molecule (Indian blood group) | -0.107907 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.08463 |
| VCL | vinculin | -0.0791754 |
| RPS24 | ribosomal protein S24 | -0.0706464 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0693586 |
| RPS16 | ribosomal protein S16 | -0.0683844 |
| ACTN4 | actinin, alpha 4 | -0.0677509 |
| TMSB10 | thymosin beta 10 | -0.0668555 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0621001 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0556291 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0512905 |
| TMEM123 | transmembrane protein 123 | -0.0510264 |
| KLF6 | Kruppel-like factor 6 | -0.0498119 |
| RTN4 | reticulon 4 | -0.04749 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0470542 |
| TMEM41B | transmembrane protein 41B | -0.0464629 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0452424 |
| TXNRD1 | thioredoxin reductase 1 | -0.045017 |
| ACTG1 | actin gamma 1 | -0.0445439 |
| CARD18 | caspase recruitment domain family, member 18 | -0.0425873 |
| MORF4L2 | mortality factor 4 like 2 | -0.0390523 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0379749 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0376847 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0364413 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0360945 |
| RPL35A | ribosomal protein L35a | -0.0355325 |
| ZNF217 | zinc finger protein 217 | -0.0352733 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0349004 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0339539 |
| IER3 | immediate early response 3 | -0.0335113 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0332962 |
| S100A10 | S100 calcium binding protein A10 | -0.0330997 |
| ANLN | anillin, actin binding protein | -0.032747 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0324745 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0321343 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0320087 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0313261 |
| PTMA | prothymosin, alpha | -0.0311625 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0309035 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0301978 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.030158 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0296566 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0293527 |
| ODF2L | outer dense fiber of sperm tails 2-like | -0.0292346 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0292083 |
| IL6ST | interleukin 6 signal transducer | -0.0289889 |
| ZNF292 | zinc finger protein 292 | -0.0288072 |
| TUBB | tubulin, beta class I | -0.0285908 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0279761 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0278134 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0276736 |
| RPLP2 | ribosomal protein, large, P2 | -0.0274573 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0273836 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -0.0273235 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0272061 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0263494 |
| ZNF546 | zinc finger protein 546 | -0.0262522 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.026232 |
| CAVIN1 | caveolae associated protein 1 | -0.0260231 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0259238 |
| RPS21 | ribosomal protein S21 | -0.0257875 |
| DHX32 | DEAH (Asp-Glu-Ala-His) box polypeptide 32 | -0.0257225 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0256228 |
| PERP | PERP, TP53 apoptosis effector | -0.0256034 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0253985 |
| NABP1 | nucleic acid binding protein 1 | -0.0253005 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | -0.0252222 |
| SPAG9 | sperm associated antigen 9 | -0.0251483 |
| FRMD5 | FERM domain containing 5 | -0.0249603 |
| MYSM1 | Myb-like, SWIRM and MPN domains 1 | -0.0245966 |
| SBF2 | SET binding factor 2 | -0.0242192 |
| SHTN1 | shootin 1 | -0.0241554 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0241012 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0240832 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0239477 |
| ITGB5 | integrin, beta 5 | -0.0239401 |
| ABLIM1 | actin binding LIM protein 1 | -0.023935 |
| YBX3 | Y box binding protein 3 | -0.0238535 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0238209 |
| FHL2 | four and a half LIM domains 2 | -0.0236923 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0234704 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0233903 |
| ANXA2 | annexin A2 | -0.0231632 |
| SMYD3 | SET and MYND domain containing 3 | -0.0231391 |
| KLHL5 | kelch-like family member 5 | -0.0228325 |
| RPL36A | ribosomal protein L36a | -0.0227512 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0225995 |
| VMP1 | vacuole membrane protein 1 | -0.022088 |
| CLTA | clathrin, light chain A | -0.0220225 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0219169 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0218162 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0217649 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0216039 |
| EGR1 | early growth response 1 | -0.0215382 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.0213733 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0212914 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0212192 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0210342 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0209894 |
