| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Balsalazide (sodium hydrate) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Balsalazide (sodium hydrate)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.145563 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.113012 |
| NRG3 | neuregulin 3 | 0.108037 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0981348 |
| NLGN1 | neuroligin 1 | 0.0975615 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0883804 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0782799 |
| MSI2 | musashi RNA-binding protein 2 | 0.0727131 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0607 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0574515 |
| DST | dystonin | 0.0571999 |
| FHIT | fragile histidine triad | 0.0570849 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.055216 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0480196 |
| LSAMP | limbic system-associated membrane protein | 0.0479599 |
| ANGPTL4 | angiopoietin-like 4 | 0.0410196 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0405345 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0402875 |
| RNF213 | ring finger protein 213 | 0.0401721 |
| RAD51B | RAD51 paralog B | 0.0399134 |
| SFTPA2 | surfactant protein A2 | 0.0395162 |
| CADM1 | cell adhesion molecule 1 | 0.0393438 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0386608 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0386112 |
| INPP5F | inositol polyphosphate-5-phosphatase F | 0.0379842 |
| EHBP1 | EH domain binding protein 1 | 0.0371132 |
| RHOA | ras homolog family member A | 0.0367204 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0354813 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0350676 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.034929 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0349061 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.034848 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0338637 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0338542 |
| ASPH | aspartate beta-hydroxylase | 0.0327351 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0323444 |
| ENO1 | enolase 1, (alpha) | 0.0320966 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0318785 |
| LDHA | lactate dehydrogenase A | 0.0316933 |
| VEGFA | vascular endothelial growth factor A | 0.0314604 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0311987 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0310176 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.0307573 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.030504 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0297461 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0295842 |
| FMNL2 | formin-like 2 | 0.0295805 |
| PHF21A | PHD finger protein 21A | 0.0294456 |
| CD109 | CD109 molecule | 0.0291785 |
| PDE10A | phosphodiesterase 10A | 0.0286232 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0282007 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0276742 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0272199 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.027068 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0269584 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0267159 |
| DPP6 | dipeptidyl-peptidase 6 | 0.0267014 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0262972 |
| CTSB | cathepsin B | 0.0262803 |
| IFI44L | interferon-induced protein 44-like | 0.0262678 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0258297 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0255396 |
| PKM | pyruvate kinase, muscle | 0.025527 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0254963 |
| FAM13A | family with sequence similarity 13, member A | 0.0252553 |
| NRP2 | neuropilin 2 | 0.025187 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0251462 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0249099 |
| PRELID2 | PRELI domain containing 2 | 0.024844 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0246671 |
| FLNA | filamin A, alpha | 0.0242462 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0239629 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0234933 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0233298 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0232952 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0231221 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0231133 |
| HDAC4 | histone deacetylase 4 | 0.0230409 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0228261 |
| MEF2A | myocyte enhancer factor 2A | 0.0228001 |
| DENND1A | DENN/MADD domain containing 1A | 0.022343 |
| SVIL | supervillin | 0.0220554 |
| TNNC1 | troponin C type 1 (slow) | 0.022023 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.0218052 |
| AUTS2 | autism susceptibility candidate 2 | 0.0217806 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0215845 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0215704 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0215133 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0213275 |
| AHNAK | AHNAK nucleoprotein | 0.021289 |
| CFAP20DC | CFAP20 domain containing | 0.0212837 |
| CUX1 | cut-like homeobox 1 | 0.0209624 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0204835 |
| TPM4 | tropomyosin 4 | 0.0201781 |
| FRMD4A | FERM domain containing 4A | 0.020071 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0200138 |
| CNKSR3 | CNKSR family member 3 | 0.0197486 |
| HLA-A | major histocompatibility complex, class I, A | 0.0196777 |
| RIGI | RNA sensor RIG-I | 0.0195709 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.019568 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.144728 |
| FMN1 | formin 1 | -0.144398 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.105459 |
| MT2A | metallothionein 2A | -0.10395 |
| TXNRD1 | thioredoxin reductase 1 | -0.101009 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0935727 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.084744 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0804251 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0743158 |
| VIM | vimentin | -0.0704017 |
| GOLGA4 | golgin A4 | -0.0667859 |
| CD44 | CD44 molecule (Indian blood group) | -0.0631974 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0613578 |
| SQSTM1 | sequestosome 1 | -0.0606314 |
| SPAG9 | sperm associated antigen 9 | -0.0588728 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0552632 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0519538 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0437597 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0427538 |
| RASAL2 | RAS protein activator like 2 | -0.0420038 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0418648 |
| CENPF | centromere protein F, 350/400kDa | -0.0406867 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0405377 |
| RPS3 | ribosomal protein S3 | -0.0402739 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0399876 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0398164 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0388218 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0384732 |
| NAV2 | neuron navigator 2 | -0.0383667 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0374747 |
| CCND1 | cyclin D1 | -0.0371972 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0371443 |
| RPS12 | ribosomal protein S12 | -0.0360141 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.034824 |
| ERBIN | erbb2 interacting protein | -0.0341139 |
| ACTG1 | actin gamma 1 | -0.0336126 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.03346 |
| RPL32 | ribosomal protein L32 | -0.0333211 |
| RTN4 | reticulon 4 | -0.0330322 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0328477 |
| RPL11 | ribosomal protein L11 | -0.0323099 |
| RPLP1 | ribosomal protein, large, P1 | -0.0302817 |
| RPS23 | ribosomal protein S23 | -0.0300788 |
| RPS6 | ribosomal protein S6 | -0.0296833 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0296031 |
| NDRG1 | N-myc downstream regulated 1 | -0.029105 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0289926 |
| RPLP2 | ribosomal protein, large, P2 | -0.0285815 |
| RPL12 | ribosomal protein L12 | -0.0283811 |
| ATP13A3 | ATPase type 13A3 | -0.0283678 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0283219 |
| RBM25 | RNA binding motif protein 25 | -0.0281043 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0280336 |
| RPS2 | ribosomal protein S2 | -0.0276556 |
| RPS13 | ribosomal protein S13 | -0.0275017 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0274931 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0273489 |
| CENPE | centromere protein E, 312kDa | -0.0269803 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0268732 |
| RPL38 | ribosomal protein L38 | -0.0265166 |
| EPG5 | ectopic P-granules autophagy protein 5 homolog (C. elegans) | -0.0263581 |
| RUNX1 | runt-related transcription factor 1 | -0.0261765 |
| OXSR1 | oxidative stress responsive 1 | -0.0258458 |
| RPL34 | ribosomal protein L34 | -0.0257573 |
| RPS24 | ribosomal protein S24 | -0.025552 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0249027 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0246795 |
| EMP1 | epithelial membrane protein 1 | -0.0246461 |
| FILIP1 | filamin A interacting protein 1 | -0.0245384 |
| PCNX4 | pecanex 4 | -0.0242534 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0241535 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0234005 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0231249 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0230825 |
| TUSC3 | tumor suppressor candidate 3 | -0.0229751 |
| RPL9 | ribosomal protein L9 | -0.0226349 |
| RPS21 | ribosomal protein S21 | -0.0225816 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0225482 |
| RPS8 | ribosomal protein S8 | -0.0225269 |
| MTPN | myotrophin | -0.0224938 |
| RPL37A | ribosomal protein L37a | -0.0222237 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0221829 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0218045 |
| RPL23 | ribosomal protein L23 | -0.0216018 |
| MAP4 | microtubule-associated protein 4 | -0.0213742 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0213725 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | -0.021255 |
| FRMD5 | FERM domain containing 5 | -0.0211045 |
| KIF4A | kinesin family member 4A | -0.0210961 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0205192 |
| RPL35A | ribosomal protein L35a | -0.0204964 |
| KIF5B | kinesin family member 5B | -0.0204815 |
| NOP58 | NOP58 ribonucleoprotein | -0.0202278 |
| UPP1 | uridine phosphorylase 1 | -0.0201099 |
| TEX10 | testis expressed 10 | -0.0199975 |
| CEP128 | centrosomal protein 128kDa | -0.0199772 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.019967 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0198155 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0197065 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0196716 |
