Balsalazide (sodium hydrate)_SW 1271 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Balsalazide (sodium hydrate) perturbation in SW 1271 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Balsalazide (sodium hydrate)_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
BHLHE40 basic helix-loop-helix family, member e40 0.101956
FMNL2 formin-like 2 0.0746924
CD44 CD44 molecule (Indian blood group) 0.0713339
NAV2 neuron navigator 2 0.0629261
ELL2 elongation factor, RNA polymerase II, 2 0.0566206
CAPRIN2 caprin family member 2 0.055429
MYH9 myosin, heavy chain 9, non-muscle 0.0530351
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.0523436
ESYT2 extended synaptotagmin-like protein 2 0.0511718
PKM pyruvate kinase, muscle 0.0509582
RNF145 ring finger protein 145 0.0501109
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.049659
BIRC3 baculoviral IAP repeat containing 3 0.0473733
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.046596
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.0463578
YAP1 Yes-associated protein 1 0.0455187
KTN1 kinectin 1 (kinesin receptor) 0.0445448
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0443872
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 0.0435854
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0432718
TXNRD1 thioredoxin reductase 1 0.0426545
NAMPT nicotinamide phosphoribosyltransferase 0.042245
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0419793
XPO1 exportin 1 0.0418221
RAB6A RAB6A, member RAS oncogene family 0.0395254
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa 0.0393572
DERA deoxyribose-phosphate aldolase (putative) 0.038513
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B 0.0381264
STK24 serine/threonine kinase 24 0.0374775
SMAD3 SMAD family member 3 0.0374652
ARRDC3 arrestin domain containing 3 0.0372973
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.0370592
COG5 component of oligomeric golgi complex 5 0.0366709
CHD1 chromodomain helicase DNA binding protein 1 0.0366454
BASP1 brain abundant, membrane attached signal protein 1 0.0363367
MSN moesin 0.035908
NGLY1 N-glycanase 1 0.0358002
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0350244
RTN4 reticulon 4 0.0346836
PBX3 pre-B-cell leukemia homeobox 3 0.0345841
FNDC3B fibronectin type III domain containing 3B 0.034537
RBM39 RNA binding motif protein 39 0.034103
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0340305
MARCHF6 membrane associated ring-CH-type finger 6 0.0339879
FAM3C family with sequence similarity 3, member C 0.033902
PDE8A phosphodiesterase 8A 0.0333125
MT2A metallothionein 2A 0.0330046
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0320098
AKAP12 A kinase (PRKA) anchor protein 12 0.031919
CEP250 centrosomal protein 250kDa 0.0318362
UBAC2 UBA domain containing 2 0.0312721
MRE11 MRE11 homolog, double strand break repair nuclease 0.0312564
CEP295 centrosomal protein 295kDa 0.0311251
OGA O-GlcNAcase 0.0309482
ZNF292 zinc finger protein 292 0.0309125
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0307079
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.0304582
SREK1 splicing regulatory glutamine/lysine-rich protein 1 0.0303337
SVIL supervillin 0.0302416
NBAS neuroblastoma amplified sequence 0.0299346
TAOK3 TAO kinase 3 0.0294858
PHF20 PHD finger protein 20 0.0291856
EEF2 eukaryotic translation elongation factor 2 0.0289292
TENT2 terminal nucleotidyltransferase 2 0.0288779
POTEF POTE ankyrin domain family, member F 0.0288624
IRAK2 interleukin-1 receptor-associated kinase 2 0.0288084
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.0285973
CSNK1A1 casein kinase 1, alpha 1 0.028561
DOCK4 dedicator of cytokinesis 4 0.0284349
TPM3 tropomyosin 3 0.0284169
TPX2 TPX2, microtubule-associated 0.0283193
DIAPH1 diaphanous-related formin 1 0.027852
USP36 ubiquitin specific peptidase 36 0.027765
IGFBP3 insulin-like growth factor binding protein 3 0.027696
RB1CC1 RB1-inducible coiled-coil 1 0.0274969
PCCA propionyl CoA carboxylase, alpha polypeptide 0.0272546
SETD5 SET domain containing 5 0.0266647
PHC3 polyhomeotic homolog 3 (Drosophila) 0.0266203
SAMD4A sterile alpha motif domain containing 4A 0.0265171
AFF1 AF4/FMR2 family, member 1 0.0263056
KDM2A lysine (K)-specific demethylase 2A 0.0262842
ECPAS Ecm29 proteasome adaptor and scaffold 0.026125
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 0.0260554
ITGB4 integrin, beta 4 0.0259603
MYO9B myosin IXB 0.0258594
NUMA1 nuclear mitotic apparatus protein 1 0.0258581
DNMBP dynamin binding protein 0.0258222
PCNX1 pecanex 1 0.0255027
CWF19L2 CWF19-like 2, cell cycle control (S. pombe) 0.0254106
WWC1 WW and C2 domain containing 1 0.0253686
SRPK2 SRSF protein kinase 2 0.0251152
CUL5 cullin 5 0.0250837
HELZ helicase with zinc finger 0.0250068
DTNA dystrobrevin, alpha 0.0249982
PDE4D phosphodiesterase 4D, cAMP-specific 0.0249588
PSME4 proteasome (prosome, macropain) activator subunit 4 0.0249322
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0247738
FLNB filamin B, beta 0.024754
ZFC3H1 zinc finger, C3H1-type containing 0.024706
AKAP13 A kinase (PRKA) anchor protein 13 0.0245928

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.236103
TPT1 tumor protein, translationally-controlled 1 -0.162049
INTS6 integrator complex subunit 6 -0.0840731
HMGA2 high mobility group AT-hook 2 -0.0763028
FMN1 formin 1 -0.0651137
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.0604088
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0585396
DPYD dihydropyrimidine dehydrogenase -0.0490757
PCNX4 pecanex 4 -0.0472908
TMSB10 thymosin beta 10 -0.0471969
ATM ATM serine/threonine kinase -0.0471487
PCED1B PC-esterase domain containing 1B -0.0457456
AEBP2 AE binding protein 2 -0.0450806
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 -0.0441171
N4BP2L2 NEDD4 binding protein 2-like 2 -0.0433431
LDHA lactate dehydrogenase A -0.0433114
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0410294
LPP LIM domain containing preferred translocation partner in lipoma -0.0405893
ATG7 autophagy related 7 -0.0395095
PNRC1 proline-rich nuclear receptor coactivator 1 -0.0383853
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0383816
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0382804
TM4SF1 transmembrane 4 L six family member 1 -0.0365539
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2 -0.0359739
RALY RALY heterogeneous nuclear ribonucleoprotein -0.0355673
ASPH aspartate beta-hydroxylase -0.0355493
CLIP1 CAP-GLY domain containing linker protein 1 -0.0354509
BRIP1 BRCA1 interacting protein C-terminal helicase 1 -0.0346863
TPI1 triosephosphate isomerase 1 -0.034564
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 -0.0344826
ANGPTL4 angiopoietin-like 4 -0.0344154
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 -0.0342478
ZBTB20 zinc finger and BTB domain containing 20 -0.03417
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa -0.0340265
PHF3 PHD finger protein 3 -0.0335195
GNAS GNAS complex locus -0.0331933
C6ORF62 chromosome 6 open reading frame 62 -0.03267
VCL vinculin -0.0321132
BTG1 B-cell translocation gene 1, anti-proliferative -0.0313515
RPL26 ribosomal protein L26 -0.0306789
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0304104
DENND1A DENN/MADD domain containing 1A -0.0300068
RPL32 ribosomal protein L32 -0.0300001
AHNAK AHNAK nucleoprotein -0.0295286
IER3 immediate early response 3 -0.0295044
TMEM14B transmembrane protein 14B -0.029419
ARHGAP5 Rho GTPase activating protein 5 -0.0294023
FUS FUS RNA binding protein -0.029233
WNT2B wingless-type MMTV integration site family, member 2B -0.0289617
CFH complement factor H -0.0279536
SLC38A2 solute carrier family 38, member 2 -0.0276465
HSPH1 heat shock 105kDa/110kDa protein 1 -0.0276295
IARS1 isoleucyl-tRNA synthetase 1 -0.027621
EIF1 eukaryotic translation initiation factor 1 -0.0272472
FUT11 fucosyltransferase 11 (alpha (1,3) fucosyltransferase) -0.0271882
VIM vimentin -0.0270904
NDRG1 N-myc downstream regulated 1 -0.0267787
RPL34 ribosomal protein L34 -0.0263587
PATJ PATJ crumbs cell polarity complex component -0.0263447
SPDYA speedy/RINGO cell cycle regulator family member A -0.0262795
NABP1 nucleic acid binding protein 1 -0.0258956
LOC112694756 uncharaterized LOC112694756 -0.0258948
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -0.0256564
APOLD1 apolipoprotein L domain containing 1 -0.0255288
ARMH4 armadillo like helical domain containing 4 -0.0254942
STXBP1 syntaxin binding protein 1 -0.0253921
TIAM2 T-cell lymphoma invasion and metastasis 2 -0.0252477
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0251985
ATG10 autophagy related 10 -0.0247603
CAVIN1 caveolae associated protein 1 -0.0246705
CCDC138 coiled-coil domain containing 138 -0.0246153
WWOX WW domain containing oxidoreductase -0.0244257
PTMA prothymosin, alpha -0.0241828
HLA-C major histocompatibility complex, class I, C -0.0241474
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -0.0240539
NCOA6 nuclear receptor coactivator 6 -0.024041
DNAAF9 dynein axonemal assembly factor 9 -0.0240087
RPS21 ribosomal protein S21 -0.0237633
GCC2 GRIP and coiled-coil domain containing 2 -0.0234426
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0233522
SLC35F3 solute carrier family 35, member F3 -0.0232014
NR6A1 nuclear receptor subfamily 6, group A, member 1 -0.0232012
TNRC6B trinucleotide repeat containing 6B -0.0230584
FAM114A1 family with sequence similarity 114, member A1 -0.0230535
GLRX glutaredoxin (thioltransferase) -0.0226905
MCTP1 multiple C2 domains, transmembrane 1 -0.022613
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.022508
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 -0.0224201
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 -0.0224145
TRIM56 tripartite motif containing 56 -0.0223193
CEP290 centrosomal protein 290kDa -0.0221564
TMEM263 transmembrane protein 263 -0.0216931
MBD5 methyl-CpG binding domain protein 5 -0.0216803
ANKRD11 ankyrin repeat domain 11 -0.0216389
STARD4 StAR-related lipid transfer (START) domain containing 4 -0.0215334
STXBP5 syntaxin binding protein 5 (tomosyn) -0.0213699
ERCC6L2 excision repair cross-complementation group 6-like 2 -0.0213641
PALM2AKAP2 PALM2 and AKAP2 fusion -0.0212799
GPR75-ASB3 GPR75-ASB3 readthrough -0.0210075
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0207474