| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Balsalazide (sodium hydrate) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Balsalazide (sodium hydrate)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | 0.145777 |
| FN1 | fibronectin 1 | 0.136049 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.07796 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.071113 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.069704 |
| HMGA2 | high mobility group AT-hook 2 | 0.06763 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0640741 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0628838 |
| STC2 | stanniocalcin 2 | 0.0495028 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0439918 |
| RAI14 | retinoic acid induced 14 | 0.0434907 |
| CADM1 | cell adhesion molecule 1 | 0.0420509 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.041792 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0375476 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0353676 |
| FAM13A | family with sequence similarity 13, member A | 0.0351432 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0334769 |
| CD109 | CD109 molecule | 0.0316262 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0306923 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0303097 |
| VEGFA | vascular endothelial growth factor A | 0.0298001 |
| EFNA5 | ephrin-A5 | 0.0294511 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0286826 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0283779 |
| FAT1 | FAT atypical cadherin 1 | 0.0283653 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0275408 |
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | 0.0256639 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0254996 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | 0.0251851 |
| TENM4 | teneurin transmembrane protein 4 | 0.0247467 |
| TMEM165 | transmembrane protein 165 | 0.0245599 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0237182 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0232735 |
| ITGA1 | integrin, alpha 1 | 0.0232115 |
| MTSS1 | metastasis suppressor 1 | 0.0227564 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0226166 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0224698 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0223866 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0216489 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.020915 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0202108 |
| LOX | lysyl oxidase | 0.0199057 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0198114 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0193285 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0190581 |
| FBN1 | fibrillin 1 | 0.0190518 |
| PLIN2 | perilipin 2 | 0.0188377 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0182402 |
| CTBP2 | C-terminal binding protein 2 | 0.0182395 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.018132 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0179482 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0172635 |
| TMEM65 | transmembrane protein 65 | 0.017194 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0170361 |
| CRTAC1 | cartilage acidic protein 1 | 0.0167804 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0165875 |
| HPS3 | Hermansky-Pudlak syndrome 3 | 0.0165287 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0163672 |
| FLNB | filamin B, beta | 0.0162905 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0162653 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0159957 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0159357 |
| SIRT1 | sirtuin 1 | 0.0156281 |
| TCIM | transcriptional and immune response regulator | 0.0155002 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.0152654 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0152016 |
| NDRG1 | N-myc downstream regulated 1 | 0.0149864 |
| LYST | lysosomal trafficking regulator | 0.0147703 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0146906 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0146518 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0146127 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0146062 |
| GPC6 | glypican 6 | 0.0142429 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0141518 |
| MLPH | melanophilin | 0.014147 |
| INTS6 | integrator complex subunit 6 | 0.0139452 |
| MYOF | myoferlin | 0.0139375 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0136976 |
| FMNL2 | formin-like 2 | 0.0136455 |
| CHGB | chromogranin B | 0.0136108 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.0134549 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0129854 |
| EGFR | epidermal growth factor receptor | 0.012892 |
| PRKCA | protein kinase C, alpha | 0.0128407 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0127539 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0123281 |
| SH3PXD2B | SH3 and PX domains 2B | 0.012268 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0117511 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.011737 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0117289 |
| DGKH | diacylglycerol kinase, eta | 0.0116939 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.0116573 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0116416 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0115761 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0115569 |
| DENND5B | DENN/MADD domain containing 5B | 0.0113344 |
| VAC14 | Vac14 homolog (S. cerevisiae) | 0.0112873 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0110894 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0109921 |
| IL6 | interleukin 6 | 0.0109638 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.23309 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.221991 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.195773 |
| MT2A | metallothionein 2A | -0.119088 |
| SQSTM1 | sequestosome 1 | -0.0804912 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0729728 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0729059 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0697883 |
| CENPF | centromere protein F, 350/400kDa | -0.0678617 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0641332 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0640348 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0619469 |
| VCL | vinculin | -0.0581799 |
| VIM | vimentin | -0.0578012 |
| TXNRD1 | thioredoxin reductase 1 | -0.0575765 |
| FTL | ferritin, light polypeptide | -0.054621 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0542331 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0538633 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0503015 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0500303 |
| TMSB10 | thymosin beta 10 | -0.0485743 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0465719 |
| HLA-B | major histocompatibility complex, class I, B | -0.0465719 |
| CANX | calnexin | -0.0459124 |
| B2M | beta-2-microglobulin | -0.0455533 |
| RBM39 | RNA binding motif protein 39 | -0.0451296 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.043715 |
| RPS12 | ribosomal protein S12 | -0.0432432 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0429746 |
| OSMR | oncostatin M receptor | -0.0421457 |
| GLIS3 | GLIS family zinc finger 3 | -0.0413266 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0407061 |
| RPS6 | ribosomal protein S6 | -0.0407059 |
| RPL12 | ribosomal protein L12 | -0.0406623 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0406055 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0404255 |
| TPR | translocated promoter region, nuclear basket protein | -0.040193 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.04002 |
| RBM25 | RNA binding motif protein 25 | -0.0399544 |
| RPL9 | ribosomal protein L9 | -0.0399378 |
| YBX3 | Y box binding protein 3 | -0.0395629 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0395431 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.039383 |
| CD44 | CD44 molecule (Indian blood group) | -0.0387984 |
| TOP1 | topoisomerase (DNA) I | -0.0386381 |
| MKI67 | marker of proliferation Ki-67 | -0.0378365 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.037585 |
| PTMA | prothymosin, alpha | -0.03704 |
| RPL26 | ribosomal protein L26 | -0.0369886 |
| RRBP1 | ribosome binding protein 1 | -0.0354078 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0345949 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0343183 |
| SEPTIN7 | septin 7 | -0.0342294 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0338452 |
| ACTN4 | actinin, alpha 4 | -0.0332914 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0332127 |
| RPS24 | ribosomal protein S24 | -0.0330952 |
| RPL35A | ribosomal protein L35a | -0.0329316 |
| RPLP1 | ribosomal protein, large, P1 | -0.0328769 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0326324 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0326311 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0324764 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.032308 |
| FNBP1 | formin binding protein 1 | -0.0322749 |
| RPS19 | ribosomal protein S19 | -0.0315312 |
| SYT1 | synaptotagmin I | -0.0313955 |
| S100A6 | S100 calcium binding protein A6 | -0.0308399 |
| RPL11 | ribosomal protein L11 | -0.0306745 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0302468 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0299013 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0296209 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0293585 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0285762 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0284982 |
| KIF5B | kinesin family member 5B | -0.0284874 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0283511 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0282143 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0280337 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0279209 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0278905 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0267712 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0267625 |
| RPL23 | ribosomal protein L23 | -0.0267291 |
| ARF1 | ADP-ribosylation factor 1 | -0.0262111 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0261862 |
| VMP1 | vacuole membrane protein 1 | -0.0261344 |
| ETV1 | ets variant 1 | -0.0260315 |
| RPS20 | ribosomal protein S20 | -0.0258878 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0257751 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.025753 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0256748 |
| TPI1 | triosephosphate isomerase 1 | -0.0254817 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0253985 |
| PELO | pelota homolog (Drosophila) | -0.0253956 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0252575 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0250597 |
| NTN4 | netrin 4 | -0.0250319 |
| GNAS | GNAS complex locus | -0.0249888 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0249749 |
| RPS21 | ribosomal protein S21 | -0.0249636 |
