| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Balsalazide (sodium hydrate) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Balsalazide (sodium hydrate)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0875769 |
| BCL2L1 | BCL2-like 1 | 0.0828303 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0749909 |
| NEBL | nebulette | 0.0737918 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0726725 |
| SMAD3 | SMAD family member 3 | 0.0592815 |
| TJP1 | tight junction protein 1 | 0.0564226 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0528585 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0526103 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0523141 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0522423 |
| WWC1 | WW and C2 domain containing 1 | 0.052083 |
| EZR | ezrin | 0.0511428 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0498902 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.049281 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.045915 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0445051 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0427815 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0417473 |
| MYO1E | myosin IE | 0.0415598 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0375506 |
| DIAPH1 | diaphanous-related formin 1 | 0.0368428 |
| VCL | vinculin | 0.0366903 |
| BRD2 | bromodomain containing 2 | 0.0362957 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0348667 |
| RALGAPB | Ral GTPase activating protein, beta subunit (non-catalytic) | 0.033486 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0327067 |
| CPNE1 | copine I | 0.0323886 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0320808 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0316973 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0316918 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0314187 |
| FLNA | filamin A, alpha | 0.031306 |
| FAM3C | family with sequence similarity 3, member C | 0.0312305 |
| FHL2 | four and a half LIM domains 2 | 0.0311988 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0309681 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0300015 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0296791 |
| COPA | coatomer protein complex, subunit alpha | 0.0290624 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0288924 |
| SVIL | supervillin | 0.0285376 |
| RHOA | ras homolog family member A | 0.0281403 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0278829 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0276461 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0272282 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0269429 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0268648 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0267712 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0262121 |
| EGFR | epidermal growth factor receptor | 0.0261541 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0261415 |
| NUP98 | nucleoporin 98kDa | 0.0256667 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0255629 |
| NXF1 | nuclear RNA export factor 1 | 0.0254952 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0252731 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0251294 |
| SPAG9 | sperm associated antigen 9 | 0.0250996 |
| YAP1 | Yes-associated protein 1 | 0.0249986 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0247123 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.024645 |
| LRRC1 | leucine rich repeat containing 1 | 0.0245533 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0244851 |
| TES | testin LIM domain protein | 0.0243413 |
| DST | dystonin | 0.0242385 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0241809 |
| RTN4 | reticulon 4 | 0.0240884 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0240577 |
| VEGFA | vascular endothelial growth factor A | 0.0240162 |
| STK24 | serine/threonine kinase 24 | 0.0238768 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0236975 |
| AMOTL2 | angiomotin like 2 | 0.0235014 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0233043 |
| ATP13A3 | ATPase type 13A3 | 0.0228537 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0227781 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0222336 |
| RASAL2 | RAS protein activator like 2 | 0.0217775 |
| KIAA0232 | KIAA0232 | 0.0217308 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0217052 |
| POTEF | POTE ankyrin domain family, member F | 0.021687 |
| TOP1 | topoisomerase (DNA) I | 0.0216635 |
| SGMS2 | sphingomyelin synthase 2 | 0.0214463 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0212621 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0211299 |
| STX3 | syntaxin 3 | 0.0209329 |
| TUFT1 | tuftelin 1 | 0.0205613 |
| NEK7 | NIMA-related kinase 7 | 0.020496 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0204806 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0203716 |
| USP47 | ubiquitin specific peptidase 47 | 0.0202889 |
| SIK3 | SIK family kinase 3 | 0.0202301 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0200006 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0199564 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0199257 |
| INO80 | INO80 complex subunit | 0.0198055 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0197267 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0195866 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.019541 |
| MALT1 | MALT1 paracaspase | 0.0193637 |
| GDI2 | GDP dissociation inhibitor 2 | 0.019343 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0192545 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.207234 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.163359 |
| TMSB10 | thymosin beta 10 | -0.146184 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.101048 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0955378 |
| FTL | ferritin, light polypeptide | -0.0878607 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0849343 |
| KRT8 | keratin 8, type II | -0.0804777 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0769869 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0768138 |
| CCND1 | cyclin D1 | -0.0750448 |
| NFIA | nuclear factor I/A | -0.0745865 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0713493 |
| EHBP1 | EH domain binding protein 1 | -0.0638883 |
| RPS6 | ribosomal protein S6 | -0.0608183 |
| NDRG1 | N-myc downstream regulated 1 | -0.0607767 |
| UBC | ubiquitin C | -0.0604166 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0600299 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0597474 |
| AHNAK | AHNAK nucleoprotein | -0.0592768 |
| RPLP1 | ribosomal protein, large, P1 | -0.0587199 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0556563 |
| TMEM123 | transmembrane protein 123 | -0.0554799 |
| GNAS | GNAS complex locus | -0.0542652 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.053605 |
| PERP | PERP, TP53 apoptosis effector | -0.0523339 |
| RPS21 | ribosomal protein S21 | -0.051636 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0515979 |
| IER3 | immediate early response 3 | -0.0512174 |
| RPL35A | ribosomal protein L35a | -0.049904 |
| EPCAM | epithelial cell adhesion molecule | -0.0493501 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0477705 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0477591 |
| RPS27A | ribosomal protein S27a | -0.0476031 |
| CADPS | Ca++-dependent secretion activator | -0.0475834 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0473699 |
| EXOC4 | exocyst complex component 4 | -0.0468362 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0451699 |
| SQSTM1 | sequestosome 1 | -0.0448915 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.044867 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0447057 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0436638 |
| RPS24 | ribosomal protein S24 | -0.0427748 |
| RPL12 | ribosomal protein L12 | -0.0425771 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0414311 |
| RPLP2 | ribosomal protein, large, P2 | -0.0413823 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0400865 |
| KRT19 | keratin 19, type I | -0.039776 |
| S100A6 | S100 calcium binding protein A6 | -0.0389048 |
| RPS12 | ribosomal protein S12 | -0.0384899 |
| RAD51B | RAD51 paralog B | -0.0378687 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0378424 |
| RPS25 | ribosomal protein S25 | -0.0378295 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.0373404 |
| H1-0 | H1.0 linker histone | -0.0372582 |
| TPM4 | tropomyosin 4 | -0.0365005 |
| ACTN4 | actinin, alpha 4 | -0.0362601 |
| PGK1 | phosphoglycerate kinase 1 | -0.0362278 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0362134 |
| S100A10 | S100 calcium binding protein A10 | -0.0361836 |
| RPL31 | ribosomal protein L31 | -0.0356544 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0356095 |
| DENND1A | DENN/MADD domain containing 1A | -0.0350012 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0348748 |
| RPS3 | ribosomal protein S3 | -0.0348338 |
| RPL23 | ribosomal protein L23 | -0.0346131 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0344616 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0343915 |
| SERINC5 | serine incorporator 5 | -0.034386 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0341786 |
| KRT18 | keratin 18, type I | -0.0336856 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0335195 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0331634 |
| B2M | beta-2-microglobulin | -0.0328133 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0324985 |
| SRRM3 | serine/arginine repetitive matrix 3 | -0.0323383 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0321039 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0318983 |
| RPL18 | ribosomal protein L18 | -0.0318495 |
| RPLP0 | ribosomal protein, large, P0 | -0.0314098 |
| XYLT1 | xylosyltransferase I | -0.0310457 |
| RPL37A | ribosomal protein L37a | -0.0308969 |
| MSI2 | musashi RNA-binding protein 2 | -0.0308885 |
| HMGA2 | high mobility group AT-hook 2 | -0.0308672 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0306903 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0306101 |
| CANX | calnexin | -0.0305161 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0296775 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0294701 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0291671 |
| RPS11 | ribosomal protein S11 | -0.0288293 |
| PKM | pyruvate kinase, muscle | -0.0288264 |
| RPS13 | ribosomal protein S13 | -0.0288092 |
| RPL32 | ribosomal protein L32 | -0.0287048 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0282661 |
| CBX3 | chromobox homolog 3 | -0.028069 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0280278 |
| RPL36A | ribosomal protein L36a | -0.027709 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0276668 |
| RPS5 | ribosomal protein S5 | -0.0272989 |