Balsalazide (sodium hydrate)_SW48 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Balsalazide (sodium hydrate) perturbation in SW48 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Balsalazide (sodium hydrate)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
EGFR epidermal growth factor receptor 0.0847003
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0495493
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0493652
CCSER1 coiled-coil serine-rich protein 1 0.046605
LAMA4 laminin, alpha 4 0.0455474
RCOR1 REST corepressor 1 0.0441886
RAD51B RAD51 paralog B 0.0322491
HMGA2 high mobility group AT-hook 2 0.0290365
AKAP13 A kinase (PRKA) anchor protein 13 0.0267966
FHIT fragile histidine triad 0.0264414
FAT1 FAT atypical cadherin 1 0.0262583
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.02619
OSBPL10 oxysterol binding protein-like 10 0.0243056
ATXN1 ataxin 1 0.0235135
NUP50 nucleoporin 50kDa 0.0223551
SLC30A10 solute carrier family 30, member 10 0.0215973
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B 0.0212628
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.0210217
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0202999
SMYD3 SET and MYND domain containing 3 0.0200269
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7 0.0199007
SMAD3 SMAD family member 3 0.0195872
ABR active BCR-related 0.019457
TBC1D5 TBC1 domain family, member 5 0.0191296
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0190923
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 0.0190807
IGSF9B immunoglobulin superfamily, member 9B 0.0190787
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.0189514
MPRIP myosin phosphatase Rho interacting protein 0.0189291
HDAC4 histone deacetylase 4 0.018822
TNS3 tensin 3 0.0186282
NCEH1 neutral cholesterol ester hydrolase 1 0.0182113
DOCK5 dedicator of cytokinesis 5 0.0181396
HSPA8 heat shock 70kDa protein 8 0.0176058
KITLG KIT ligand 0.0175928
ZHX2 zinc fingers and homeoboxes 2 0.0175901
MTUS1 microtubule associated tumor suppressor 1 0.0174793
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.0173506
SAMD4A sterile alpha motif domain containing 4A 0.0172179
SYNE2 spectrin repeat containing, nuclear envelope 2 0.0152749
GATAD2A GATA zinc finger domain containing 2A 0.0146831
ZNRF3 zinc and ring finger 3 0.014126
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.0137167
PARD3B par-3 family cell polarity regulator beta 0.0136477
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 0.0136175
PRELID2 PRELI domain containing 2 0.0134272
MYO5B myosin VB 0.0133674
MBNL1 muscleblind-like splicing regulator 1 0.0133571
AHNAK AHNAK nucleoprotein 0.0132492
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.0130655
EFNB2 ephrin-B2 0.012243
SH3RF2 SH3 domain containing ring finger 2 0.0121473
WWOX WW domain containing oxidoreductase 0.0121468
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.0119442
ATL2 atlastin GTPase 2 0.0118696
TRAPPC9 trafficking protein particle complex 9 0.0118555
FHL2 four and a half LIM domains 2 0.0117999
RRM2 ribonucleotide reductase M2 0.0117271
SGMS2 sphingomyelin synthase 2 0.0114017
EHBP1 EH domain binding protein 1 0.0113543
USP9X ubiquitin specific peptidase 9, X-linked 0.0112143
SAMD5 sterile alpha motif domain containing 5 0.0111904
CMIP c-Maf inducing protein 0.0111376
CLDND1 claudin domain containing 1 0.0110675
EXOC4 exocyst complex component 4 0.0108198
RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 0.0107303
SPRED2 sprouty-related, EVH1 domain containing 2 0.0105224
FRMD8 FERM domain containing 8 0.0104184
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.0103868
LGALS12 lectin, galactoside-binding, soluble, 12 0.0102758
RASAL2 RAS protein activator like 2 0.0102684
VPS13B vacuolar protein sorting 13 homolog B (yeast) 0.010255
FLNA filamin A, alpha 0.0102088
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 0.0101144
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1) 0.010095
DIAPH3 diaphanous-related formin 3 0.0100819
EGR3 early growth response 3 0.00990392
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 0.00989834
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.00981492
SERTAD2 SERTA domain containing 2 0.00978727
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.00970596
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.00967158
FOS FBJ murine osteosarcoma viral oncogene homolog 0.00965721
LEMD1 LEM domain containing 1 0.00959615
EPHA2 EPH receptor A2 0.00947653
KSR2 kinase suppressor of ras 2 0.00943414
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.0094308
CREB5 cAMP responsive element binding protein 5 0.00940908
UTRN utrophin 0.00937402
FBXL17 F-box and leucine-rich repeat protein 17 0.00935243
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8 0.00934623
DOCK1 dedicator of cytokinesis 1 0.00933799
JARID2 jumonji, AT rich interactive domain 2 0.00929663
SCFD1 sec1 family domain containing 1 0.00925611
SPIDR scaffolding protein involved in DNA repair 0.00924424
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit 0.00921812
BICD1 bicaudal D homolog 1 (Drosophila) 0.00912075
NFIB nuclear factor I/B 0.00898035
DSPP dentin sialophosphoprotein 0.00895928
MTA1 metastasis associated 1 0.00895108

decreased expression

Symbol Name Standardized Value
PTMA prothymosin, alpha -0.274195
RPS6 ribosomal protein S6 -0.169911
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.164314
TPT1 tumor protein, translationally-controlled 1 -0.160827
RPL35A ribosomal protein L35a -0.131169
IER3 immediate early response 3 -0.121452
RPS8 ribosomal protein S8 -0.10277
TMSB10 thymosin beta 10 -0.0964707
RPL26 ribosomal protein L26 -0.0931103
RPLP1 ribosomal protein, large, P1 -0.0929431
RPL37A ribosomal protein L37a -0.0915612
RPL34 ribosomal protein L34 -0.0862765
ACTG1 actin gamma 1 -0.0840766
RPS3 ribosomal protein S3 -0.0830323
RPS24 ribosomal protein S24 -0.0827919
RPS12 ribosomal protein S12 -0.0762061
RPS29 ribosomal protein S29 -0.074089
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0726852
RPS19 ribosomal protein S19 -0.0717373
RPL12 ribosomal protein L12 -0.0715509
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0713136
RPL9 ribosomal protein L9 -0.0707991
RPS13 ribosomal protein S13 -0.0698499
RPLP2 ribosomal protein, large, P2 -0.0696761
EIF1 eukaryotic translation initiation factor 1 -0.0651371
RPL11 ribosomal protein L11 -0.0641865
RPL31 ribosomal protein L31 -0.0640323
RPS27A ribosomal protein S27a -0.0636446
RPS25 ribosomal protein S25 -0.0612557
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0596271
RPL23 ribosomal protein L23 -0.057702
RPL32 ribosomal protein L32 -0.0562387
RPL5 ribosomal protein L5 -0.0558165
RPLP0 ribosomal protein, large, P0 -0.0532898
HLA-B major histocompatibility complex, class I, B -0.0518875
RPL7A ribosomal protein L7a -0.0515397
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0512767
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I -0.0503607
AREG amphiregulin -0.0498495
ANXA1 annexin A1 -0.0495231
RPL19 ribosomal protein L19 -0.0490749
RPS21 ribosomal protein S21 -0.0488827
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0456016
GOLGA4 golgin A4 -0.0454578
RPS14 ribosomal protein S14 -0.045289
RPS23 ribosomal protein S23 -0.0445863
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0430845
RPS17 ribosomal protein S17 -0.0429554
RPL36 ribosomal protein L36 -0.0426317
NAP1L1 nucleosome assembly protein 1-like 1 -0.04243
S100A6 S100 calcium binding protein A6 -0.0421082
RACK1 receptor for activated C kinase 1 -0.0417652
RPS15 ribosomal protein S15 -0.0416808
LDHA lactate dehydrogenase A -0.0404009
RPS2 ribosomal protein S2 -0.0393388
LOC102724023 ES1 protein homolog, mitochondrial -0.0391742
MT2A metallothionein 2A -0.0387543
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.03855
RPL17-C18ORF32 RPL17-C18orf32 readthrough -0.0383837
RPL8 ribosomal protein L8 -0.0383364
RPS10 ribosomal protein S10 -0.0383307
RPL37 ribosomal protein L37 -0.036984
RPL36A ribosomal protein L36a -0.0363933
RPL38 ribosomal protein L38 -0.0363032
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha -0.0361377
RPL7 ribosomal protein L7 -0.0356749
RPL15 ribosomal protein L15 -0.03483
RPS5 ribosomal protein S5 -0.0343975
RPL13A ribosomal protein L13a -0.0342687
RPL28 ribosomal protein L28 -0.0342438
RPS11 ribosomal protein S11 -0.0340806
PRRC2C proline-rich coiled-coil 2C -0.0340489
RPS27 ribosomal protein S27 -0.0339946
GARS1 glycyl-tRNA synthetase 1 -0.0334075
RPS16 ribosomal protein S16 -0.033308
EREG epiregulin -0.0325782
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0317709
RAB1A RAB1A, member RAS oncogene family -0.031578
PNISR PNN-interacting serine/arginine-rich protein -0.0307318
FTL ferritin, light polypeptide -0.03026
RPS4X ribosomal protein S4, X-linked -0.0302196
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0297129
MTDH metadherin -0.0296953
LAMB3 laminin, beta 3 -0.0295793
TPM4 tropomyosin 4 -0.0294529
NDRG1 N-myc downstream regulated 1 -0.0288039
RBM39 RNA binding motif protein 39 -0.0284926
PKM pyruvate kinase, muscle -0.0282782
PDE4B phosphodiesterase 4B, cAMP-specific -0.0280063
S100A10 S100 calcium binding protein A10 -0.0276267
ENO1 enolase 1, (alpha) -0.0274977
RPL27A ribosomal protein L27a -0.027289
SEPTIN7 septin 7 -0.0270178
RPL10A ribosomal protein L10a -0.0265864
VIM vimentin -0.0265439
HMGA1 high mobility group AT-hook 1 -0.0262957
EIF5B eukaryotic translation initiation factor 5B -0.0259146
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.0258763
EEF1B2 eukaryotic translation elongation factor 1 beta 2 -0.0256913
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0256684