Balsalazide (sodium hydrate)_SW480 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Balsalazide (sodium hydrate) perturbation in SW480 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Balsalazide (sodium hydrate)_SW480 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.249019
NAV2 neuron navigator 2 0.160655
NKD1 naked cuticle homolog 1 (Drosophila) 0.121658
SDK1 sidekick cell adhesion molecule 1 0.105222
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0914571
ANO1 anoctamin 1, calcium activated chloride channel 0.0794567
ASPH aspartate beta-hydroxylase 0.0757821
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 0.0714845
AKAP12 A kinase (PRKA) anchor protein 12 0.071287
ADGRL2 adhesion G protein-coupled receptor L2 0.0685097
CDH13 cadherin 13 0.0681659
BACE2 beta-site APP-cleaving enzyme 2 0.0610706
WWOX WW domain containing oxidoreductase 0.0559997
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0514751
SKAP1 src kinase associated phosphoprotein 1 0.0498558
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.049439
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0467374
RAD51B RAD51 paralog B 0.0466023
PLEC plectin 0.045016
EXOC4 exocyst complex component 4 0.0424637
KIZ kizuna centrosomal protein 0.0422547
HDAC4 histone deacetylase 4 0.0422182
HSPA8 heat shock 70kDa protein 8 0.0421049
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.0396659
MRPS6 mitochondrial ribosomal protein S6 0.0385991
NPAS2 neuronal PAS domain protein 2 0.037897
FRMD5 FERM domain containing 5 0.0367184
ITGB4 integrin, beta 4 0.0348067
CCND1 cyclin D1 0.0345802
CD44 CD44 molecule (Indian blood group) 0.0327596
AXIN2 axin 2 0.0326613
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1 0.0320752
FNIP1 folliculin interacting protein 1 0.0318194
MSN moesin 0.0314283
BHLHE40 basic helix-loop-helix family, member e40 0.0309528
CBX5 chromobox homolog 5 0.0304125
AHNAK AHNAK nucleoprotein 0.0302718
CDK6 cyclin-dependent kinase 6 0.0296054
POTEF POTE ankyrin domain family, member F 0.0295797
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.0289758
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.0286583
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.028555
LRMDA leucine rich melanocyte differentiation associated 0.0284788
ESYT2 extended synaptotagmin-like protein 2 0.02827
TNIK TRAF2 and NCK interacting kinase 0.0279898
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0277901
MACF1 microtubule-actin crosslinking factor 1 0.0277493
MYH9 myosin, heavy chain 9, non-muscle 0.0276991
FLNB filamin B, beta 0.0275524
IGF1R insulin-like growth factor 1 receptor 0.0271871
PKM pyruvate kinase, muscle 0.0270277
ACTN1 actinin, alpha 1 0.0260381
CMIP c-Maf inducing protein 0.0257809
GNPDA1 glucosamine-6-phosphate deaminase 1 0.0256027
GULP1 GULP, engulfment adaptor PTB domain containing 1 0.0255958
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.025472
MYOF myoferlin 0.0250082
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0248616
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.024774
RPL3 ribosomal protein L3 0.0239911
MAML2 mastermind-like 2 (Drosophila) 0.0239399
PCDH9 protocadherin 9 0.0238428
FAT1 FAT atypical cadherin 1 0.0236639
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5 0.0233878
VEGFA vascular endothelial growth factor A 0.0232314
ZNF704 zinc finger protein 704 0.022895
LPP LIM domain containing preferred translocation partner in lipoma 0.0228671
FTH1 ferritin, heavy polypeptide 1 0.0224239
AIG1 androgen-induced 1 0.0222724
HPCAL1 hippocalcin-like 1 0.0221571
PDGFA platelet-derived growth factor alpha polypeptide 0.0220762
CADM1 cell adhesion molecule 1 0.0220646
NTSR1 neurotensin receptor 1 (high affinity) 0.02203
GTF2IRD1 GTF2I repeat domain containing 1 0.0218816
RHOA ras homolog family member A 0.0217183
SAMD4A sterile alpha motif domain containing 4A 0.021459
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.02093
SRRM2 serine/arginine repetitive matrix 2 0.0209242
CSMD3 CUB and Sushi multiple domains 3 0.0208654
PTPRJ protein tyrosine phosphatase, receptor type, J 0.0206969
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0206154
PTMA prothymosin, alpha 0.0205271
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.0205232
TBC1D4 TBC1 domain family, member 4 0.0204998
FHIT fragile histidine triad 0.0203982
ZBTB20 zinc finger and BTB domain containing 20 0.0203957
TPM3 tropomyosin 3 0.0202477
CLIP2 CAP-GLY domain containing linker protein 2 0.020132
KRT18 keratin 18, type I 0.0200486
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.0199647
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.0197865
CUX1 cut-like homeobox 1 0.0197609
DSPP dentin sialophosphoprotein 0.0197156
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.0196801
SEPTIN9 septin 9 0.019609
COBL cordon-bleu WH2 repeat protein 0.0195102
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.0193727
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.0191498
HSPH1 heat shock 105kDa/110kDa protein 1 0.0191315
CLSTN2 calsyntenin 2 0.0189806

decreased expression

Symbol Name Standardized Value
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.168911
LOC102724023 ES1 protein homolog, mitochondrial -0.0782931
EIF1 eukaryotic translation initiation factor 1 -0.0609708
GARS1 glycyl-tRNA synthetase 1 -0.0593747
IARS1 isoleucyl-tRNA synthetase 1 -0.0567507
MORF4L2 mortality factor 4 like 2 -0.0543154
TMSB10 thymosin beta 10 -0.0524589
TPT1 tumor protein, translationally-controlled 1 -0.0516565
LMO7 LIM domain 7 -0.0511956
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 -0.0507466
RPS24 ribosomal protein S24 -0.0472895
SYT1 synaptotagmin I -0.0447694
EZR ezrin -0.0444063
NAP1L1 nucleosome assembly protein 1-like 1 -0.0440711
EGR1 early growth response 1 -0.0433939
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -0.0427423
ETNK1 ethanolamine kinase 1 -0.0421078
RPS3 ribosomal protein S3 -0.0418561
RPL26 ribosomal protein L26 -0.0412355
ACTG1 actin gamma 1 -0.0407357
GCC2 GRIP and coiled-coil domain containing 2 -0.0406068
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -0.0399893
RPL11 ribosomal protein L11 -0.0397832
VMP1 vacuole membrane protein 1 -0.0394614
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.0390969
DIAPH3 diaphanous-related formin 3 -0.0390968
RPL12 ribosomal protein L12 -0.0388413
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0386212
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 -0.038575
PERP PERP, TP53 apoptosis effector -0.038502
PCLO piccolo presynaptic cytomatrix protein -0.0383669
RAD21 RAD21 homolog (S. pombe) -0.0367295
PRRC2C proline-rich coiled-coil 2C -0.0357225
RBM39 RNA binding motif protein 39 -0.0356827
THOC2 THO complex 2 -0.0356568
SEC31A SEC31 homolog A (S. cerevisiae) -0.0347974
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0347319
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 -0.0343713
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.0339063
CCDC82 coiled-coil domain containing 82 -0.0338106
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0333903
SMC4 structural maintenance of chromosomes 4 -0.0332877
RPS27A ribosomal protein S27a -0.0332644
SPRED2 sprouty-related, EVH1 domain containing 2 -0.0327467
RBM25 RNA binding motif protein 25 -0.0324822
VCL vinculin -0.0322658
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0320443
RACK1 receptor for activated C kinase 1 -0.031526
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0312613
RPL32 ribosomal protein L32 -0.0311095
NCEH1 neutral cholesterol ester hydrolase 1 -0.0310946
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -0.0310733
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.0308205
OXR1 oxidation resistance 1 -0.030458
DUSP6 dual specificity phosphatase 6 -0.0297542
RPL23 ribosomal protein L23 -0.0297494
FOXP1 forkhead box P1 -0.0296774
SVIL supervillin -0.0290779
TMEM123 transmembrane protein 123 -0.0290559
EFNB2 ephrin-B2 -0.0289638
TMEM41B transmembrane protein 41B -0.0289619
RPLP1 ribosomal protein, large, P1 -0.0286115
TJP1 tight junction protein 1 -0.0286024
RPL35A ribosomal protein L35a -0.028343
SLC38A2 solute carrier family 38, member 2 -0.0281242
RPL9 ribosomal protein L9 -0.0280693
RPS4X ribosomal protein S4, X-linked -0.0279749
CTNND1 catenin (cadherin-associated protein), delta 1 -0.0278566
MT2A metallothionein 2A -0.0278296
NF1 neurofibromin 1 -0.0276964
RPLP0 ribosomal protein, large, P0 -0.0276089
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0275324
DCBLD2 discoidin, CUB and LCCL domain containing 2 -0.0274627
RPL19 ribosomal protein L19 -0.0272795
COPB2 coatomer protein complex, subunit beta 2 (beta prime) -0.027144
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0264422
AKAP9 A kinase (PRKA) anchor protein 9 -0.0262704
JUN jun proto-oncogene -0.0261013
MYL12B myosin, light chain 12B, regulatory -0.026064
ACTN4 actinin, alpha 4 -0.0260336
PIBF1 progesterone immunomodulatory binding factor 1 -0.02596
TOP1 topoisomerase (DNA) I -0.025735
MON2 MON2 homolog (S. cerevisiae) -0.025613
NKTR natural killer cell triggering receptor -0.0254952
ZFAND3 zinc finger, AN1-type domain 3 -0.0250856
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric -0.024718
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0244917
RPL18 ribosomal protein L18 -0.0243758
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -0.0243606
NEBL nebulette -0.0240397
RPL36A ribosomal protein L36a -0.023988
KLF6 Kruppel-like factor 6 -0.0239839
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 -0.0238041
ANXA2 annexin A2 -0.0236814
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.0236157
SPATA13 spermatogenesis associated 13 -0.0234023
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) -0.0233959
DLG1 discs, large homolog 1 (Drosophila) -0.0233239
GOLGA4 golgin A4 -0.0232969
H3-3B H3.3 histone B -0.0231693