Barasertib Gene Set

Dataset LINCS KinomeScan Kinase Inhibitor Targets
Category physical interactions
Type small molecule
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Genes

20 kinases inhibited by the Barasertib small molecule from the KinomeScan Kinase Inhibitor Targets dataset.

Symbol Name Standardized Value
AURKB aurora kinase B 1.35325
RET ret proto-oncogene 1.34449
FLT3 fms-related tyrosine kinase 3 1.33582
EPHB6 EPH receptor B6 1.30212
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 1.28583
AXL AXL receptor tyrosine kinase 1.25436
LCK LCK proto-oncogene, Src family tyrosine kinase 1.19568
MUSK muscle, skeletal, receptor tyrosine kinase 1.12373
EGFR epidermal growth factor receptor 1.09415
ERBB4 erb-b2 receptor tyrosine kinase 4 1.08283
HIPK4 homeodomain interacting protein kinase 4 1.05577
CSF1R colony stimulating factor 1 receptor 1.03041
MKNK2 MAP kinase interacting serine/threonine kinase 2 0.967615
AURKA aurora kinase A 0.963557
CDK11B cyclin-dependent kinase 11B 0.963557
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.959553
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.9517
BTK Bruton agammaglobulinemia tyrosine kinase 0.936602
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.902136
BLK BLK proto-oncogene, Src family tyrosine kinase 0.860727