Barrett Esophagus Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C1333324
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Genes

449 genes associated with the disease Barrett Esophagus in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ACE angiotensin I converting enzyme
ACTB actin, beta
ADAM9 ADAM metallopeptidase domain 9
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR1 adiponectin receptor 1
ADIPOR2 adiponectin receptor 2
ADRB2 adrenoceptor beta 2, surface
AGO3 argonaute RISC catalytic component 3
AGR2 anterior gradient 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AICDA activation-induced cytidine deaminase
AKAP12 A kinase (PRKA) anchor protein 12
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C2 aldo-keto reductase family 1, member C2
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
AMACR alpha-methylacyl-CoA racemase
AMPD1 adenosine monophosphate deaminase 1
ANPEP alanyl (membrane) aminopeptidase
ANXA1 annexin A1
ANXA10 annexin A10
APC adenomatous polyposis coli
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOB apolipoprotein B
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
APRT adenine phosphoribosyltransferase
ARID1A AT rich interactive domain 1A (SWI-like)
ASCC1 activating signal cointegrator 1 complex subunit 1
ATM ATM serine/threonine kinase
ATOH1 atonal homolog 1 (Drosophila)
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide
AXIN2 axin 2
AZIN2 antizyme inhibitor 2
B3GAT2 beta-1,3-glucuronyltransferase 2
BARX1 BARX homeobox 1
BCAR1 breast cancer anti-estrogen resistance 1
BCL2 B-cell CLL/lymphoma 2
BCL3 B-cell CLL/lymphoma 3
BECN1 beclin 1, autophagy related
BEST2 bestrophin 2
BEST3 bestrophin 3
BFAR bifunctional apoptosis regulator
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMP4 bone morphogenetic protein 4
BNC2 basonuclin 2
BRCA1 breast cancer 1, early onset
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C17ORF97 chromosome 17 open reading frame 97
C9 complement component 9
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CCKBR cholecystokinin B receptor
CCN1 cellular communication network factor 1
CCNA2 cyclin A2
CCND1 cyclin D1
CD1A CD1a molecule
CD44 CD44 molecule (Indian blood group)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD80 CD80 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH13 cadherin 13
CDH17 cadherin 17, LI cadherin (liver-intestine)
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDK9 cyclin-dependent kinase 9
CDKN2A cyclin-dependent kinase inhibitor 2A
CDO1 cysteine dioxygenase type 1
CDX1 caudal type homeobox 1
CDX2 caudal type homeobox 2
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CEP72 centrosomal protein 72kDa
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CKAP4 cytoskeleton-associated protein 4
CLDN2 claudin 2
CLDN4 claudin 4
CLDN7 claudin 7
COL1A1 collagen, type I, alpha 1
COMMD3-BMI1 COMMD3-BMI1 readthrough
COX1
COX2
CRTC1 CREB regulated transcription coactivator 1
CRYZ crystallin, zeta (quinone reductase)
CSE1L CSE1 chromosome segregation 1-like (yeast)
CTHRC1 collagen triple helix repeat containing 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CTSD cathepsin D
CTSE cathepsin E
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DAD1 defender against cell death 1
DAPK1 death-associated protein kinase 1
DCC DCC netrin 1 receptor
DCLK1 doublecortin-like kinase 1
DCTN6 dynactin 6
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DEFB1 defensin, beta 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNASE1 deoxyribonuclease I
DPP4 dipeptidyl-peptidase 4
E2F3 E2F transcription factor 3
EDN1 endothelin 1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
ELANE elastase, neutrophil expressed
ENG endoglin
EPC2 enhancer of polycomb homolog 2 (Drosophila)
EPCAM epithelial cell adhesion molecule
EPHB4 EPH receptor B4
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC2 excision repair cross-complementation group 2
ESR1 estrogen receptor 1
EYA4 EYA transcriptional coactivator and phosphatase 4
F2R coagulation factor II (thrombin) receptor
FABP1 fatty acid binding protein 1, liver
FABP6 fatty acid binding protein 6, ileal
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FASN fatty acid synthase
FGF1 fibroblast growth factor 1 (acidic)
FGF2 fibroblast growth factor 2 (basic)
FGFR2 fibroblast growth factor receptor 2
FH fumarate hydratase
FHIT fragile histidine triad
FN1 fibronectin 1
FNDC3B fibronectin type III domain containing 3B
FOSL1 FOS-like antigen 1
FOXA2 forkhead box A2
FOXA3 forkhead box A3
FOXF1 forkhead box F1
FOXP1 forkhead box P1
FOXP3 forkhead box P3
FRZB frizzled-related protein
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GADL1 glutamate decarboxylase-like 1
GAST gastrin
GATA6 GATA binding protein 6
GDF15 growth differentiation factor 15
GDF7 growth differentiation factor 7
GHR growth hormone receptor
GJC2 gap junction protein, gamma 2, 47kDa
GKN1 gastrokine 1
GNAS GNAS complex locus
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
GOLM1 golgi membrane protein 1
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GPBAR1 G protein-coupled bile acid receptor 1
GPX1 glutathione peroxidase 1
GPX2 glutathione peroxidase 2
GPX3 glutathione peroxidase 3
GPX7 glutathione peroxidase 7
GRB7 growth factor receptor-bound protein 7
GSTK1 glutathione S-transferase kappa 1
GSTM1 glutathione S-transferase mu 1
GSTM2 glutathione S-transferase mu 2 (muscle)
GSTO1 glutathione S-transferase omega 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
H2AX H2A.X variant histone
HAS2 hyaluronan synthase 2
HFE hemochromatosis
HGD homogentisate 1,2-dioxygenase
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGB1 high mobility group box 1
HNF1A HNF1 homeobox A
HNF4A hepatocyte nuclear factor 4, alpha
HOXB6 homeobox B6
HOXB7 homeobox B7
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HPGDS hematopoietic prostaglandin D synthase
HPSE heparanase
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA14 heat shock 70kDa protein 14
HSPA4 heat shock 70kDa protein 4
HSPB1 heat shock 27kDa protein 1
HSPB2 heat shock 27kDa protein 2
HSPB3 heat shock 27kDa protein 3
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic
ICAM1 intercellular adhesion molecule 1
ICAM2 intercellular adhesion molecule 2
ICAM3 intercellular adhesion molecule 3
IFI27 interferon, alpha-inducible protein 27
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNG interferon, gamma
IFNK interferon, kappa
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP3 insulin-like growth factor binding protein 3
IGFBP7 insulin-like growth factor binding protein 7
IKBIP IKBKB interacting protein
IL10 interleukin 10
IL12B interleukin 12B
IL17A interleukin 17A
IL18 interleukin 18
IL18RAP interleukin 18 receptor accessory protein
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL2 interleukin 2
IL23R interleukin 23 receptor
IL6 interleukin 6
INSRR insulin receptor-related receptor
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
ITLN1 intelectin 1 (galactofuranose binding)
JAG1 jagged 1
JMJD1C jumonji domain containing 1C
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KEAP1 kelch-like ECH-associated protein 1
KLF4 Kruppel-like factor 4 (gut)
KLF5 Kruppel-like factor 5 (intestinal)
KLRC1 killer cell lectin-like receptor subfamily C, member 1
KLRC4-KLRK1 KLRC4-KLRK1 readthrough
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT14 keratin 14, type I
KRT20 keratin 20, type I
KRT5 keratin 5, type II
LEP leptin
LEPR leptin receptor
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LTA lymphotoxin alpha
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAL mal, T-cell differentiation protein
MAPK8 mitogen-activated protein kinase 8
MARK2 MAP/microtubule affinity-regulating kinase 2
MAX MYC associated factor X
MCC mutated in colorectal cancers
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFAP1 microfibrillar-associated protein 1
MGMT O-6-methylguanine-DNA methyltransferase
MGST1 microsomal glutathione S-transferase 1
MICA MHC class I polypeptide-related sequence A
MICB MHC class I polypeptide-related sequence B
MKI67 marker of proliferation Ki-67
MLH1 mutL homolog 1
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MPG N-methylpurine-DNA glycosylase
MSH2 mutS homolog 2
MSH5 mutS homolog 5
MSH6 mutS homolog 6
MSI1 musashi RNA-binding protein 1
MSR1 macrophage scavenger receptor 1
MSRA methionine sulfoxide reductase A
MSX1 msh homeobox 1
MTAP methylthioadenosine phosphorylase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MUC1 mucin 1, cell surface associated
MUC17 mucin 17, cell surface associated
MUC2 mucin 2, oligomeric mucus/gel-forming
MUC3A mucin 3A, cell surface associated
MUC3B mucin 3B, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MUC6 mucin 6, oligomeric mucus/gel-forming
MXD1 MAX dimerization protein 1
MXI1 MAX interactor 1, dimerization protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO9B myosin IXB
NELL1 NEL-like 1 (chicken)
NES nestin
NET1 neuroepithelial cell transforming 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOTCH1 notch 1
NOTCH2 notch 2
NOTCH3 notch 3
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NQO1 NAD(P)H dehydrogenase, quinone 1
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR1I2 nuclear receptor subfamily 1, group I, member 2
OGG1 8-oxoguanine DNA glycosylase
OMA1 OMA1 zinc metallopeptidase
OR12D3 olfactory receptor, family 12, subfamily D, member 3
OR5V1 olfactory receptor, family 5, subfamily V, member 1
OXTR oxytocin receptor
PARP1 poly (ADP-ribose) polymerase 1
PCGF5 polycomb group ring finger 5
PCNA proliferating cell nuclear antigen
PDCD1LG2 programmed cell death 1 ligand 2
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDIA3 protein disulfide isomerase family A, member 3
PGC progastricsin (pepsinogen C)
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PITX1 paired-like homeodomain 1
PKP1 plakophilin 1
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
POTEF POTE ankyrin domain family, member F
POU5F1 POU class 5 homeobox 1
PPA1 pyrophosphatase (inorganic) 1
PPARG peroxisome proliferator-activated receptor gamma
PPIE peptidylprolyl isomerase E (cyclophilin E)
PROM1 prominin 1
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGES prostaglandin E synthase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RAD21 RAD21 homolog (S. pombe)
RBP1 retinol binding protein 1, cellular
REG1A regenerating islet-derived 1 alpha
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
REN renin
RFC3 replication factor C (activator 1) 3, 38kDa
RFX1 regulatory factor X, 1 (influences HLA class II expression)
RIN2 Ras and Rab interactor 2
RMC1 regulator of MON1-CCZ1
RNF11 ring finger protein 11
RNF121 ring finger protein 121
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RNF130 ring finger protein 130
RNF139 ring finger protein 139
RNF14 ring finger protein 14
RNF141 ring finger protein 141
RNF24 ring finger protein 24
RNF32 ring finger protein 32
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
RPE65 retinal pigment epithelium-specific protein 65kDa
RPP21 ribonuclease P/MRP 21kDa subunit
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RTRAF RNA transcription, translation and transport factor
RUNX3 runt-related transcription factor 3
S100A2 S100 calcium binding protein A2
S100A4 S100 calcium binding protein A4
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S1PR1 sphingosine-1-phosphate receptor 1
SAFB scaffold attachment factor B
SAGE1 sarcoma antigen 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SCO2 SCO2 cytochrome c oxidase assembly protein
SELENBP1 selenium binding protein 1
SFRP1 secreted frizzled-related protein 1
SFRP2 secreted frizzled-related protein 2
SHBG sex hormone-binding globulin
SI sucrase-isomaltase (alpha-glucosidase)
SKI SKI proto-oncogene
SKIL SKI-like proto-oncogene
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC22A18 solute carrier family 22, member 18
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLCO6A1 solute carrier organic anion transporter family, member 6A1
SMAD4 SMAD family member 4
SNAI2 snail family zinc finger 2
SOAT1 sterol O-acyltransferase 1
SOCS1 suppressor of cytokine signaling 1
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOX2 SRY (sex determining region Y)-box 2
SOX9 SRY (sex determining region Y)-box 9
SPAG11A sperm associated antigen 11A
SPAG11B sperm associated antigen 11B
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPINK4 serine peptidase inhibitor, Kazal type 4
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
SST somatostatin
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TAC1 tachykinin, precursor 1
TAS2R13 taste receptor, type 2, member 13
TBX5 T-box 5
TERT telomerase reverse transcriptase
TFF1 trefoil factor 1
TFF2 trefoil factor 2
TFF3 trefoil factor 3 (intestinal)
TFPI2 tissue factor pathway inhibitor 2
TGFB1 transforming growth factor, beta 1
TGM2 transglutaminase 2
THEMIS thymocyte selection associated
TICAM2 toll-like receptor adaptor molecule 2
TIMP1 TIMP metallopeptidase inhibitor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TMED7 transmembrane emp24 protein transport domain containing 7
TMED7-TICAM2 TMED7-TICAM2 readthrough
TMEFF2 transmembrane protein with EGF-like and two follistatin-like domains 2
TMOD1 tropomodulin 1
TNC tenascin C
TNF tumor necrosis factor
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TP53 tumor protein p53
TP63 tumor protein p63
TPPP tubulin polymerization promoting protein
TREX1 three prime repair exonuclease 1
TRIB3 tribbles pseudokinase 3
TRIM21 tripartite motif containing 21
TRIM31 tripartite motif containing 31
TRIM39 tripartite motif containing 39
TRIM39-RPP21 TRIM39-RPP21 readthrough
TSPAN18 tetraspanin 18
TSPYL2 TSPY-like 2
TYMP thymidine phosphorylase
TYMS thymidylate synthetase
UBE2C ubiquitin-conjugating enzyme E2C
UBL5 ubiquitin-like 5
UVRAG UV radiation resistance associated
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIM vimentin
VPS35L VPS35 endosomal protein sorting factor like
VSIG10L V-set and immunoglobulin domain containing 10 like
VTN vitronectin
WIF1 WNT inhibitory factor 1
WNT2 wingless-type MMTV integration site family member 2
WNT3A wingless-type MMTV integration site family, member 3A
WNT5A wingless-type MMTV integration site family, member 5A
XPR1 xenotropic and polytropic retrovirus receptor 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZEB1 zinc finger E-box binding homeobox 1
ZNF217 zinc finger protein 217
ZNF569 zinc finger protein 569
ZNF682 zinc finger protein 682
ZNF793 zinc finger protein 793