Behcet Syndrome Gene Set

Dataset dbGAP Gene-Trait Associations
Category disease or phenotype associations
Type trait
Description A vasculitis that is characterized by an autoimmune mediated inflammation of the blood vessels throughout the body leading to ulcerations on the mouth and sometimes the genitals, notorious for causing hypopyon uveitis. (Human Disease Ontology, DOID_13241)
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Genes

59 genes associated with the trait Behcet Syndrome in GWAS and other genetic association datasets from the dbGAP Gene-Trait Associations dataset.

Symbol Name Standardized Value
HLA-B major histocompatibility complex, class I, B 1.6248
IL10 interleukin 10 1.32685
CCHCR1 coiled-coil alpha-helical rod protein 1 1.1335
HCP5 HLA complex P5 (non-protein coding) 1.03781
PSORS1C1 psoriasis susceptibility 1 candidate 1 1.03517
MOG myelin oligodendrocyte glycoprotein 0.989283
DHFRP2 dihydrofolate reductase pseudogene 2 0.979065
C6ORF15 chromosome 6 open reading frame 15 0.945073
ZNRD1-AS1 ZNRD1 antisense RNA 1 0.908474
3.8-1.5 HLA complex group 26 (non-protein coding) pseudogene 0.828959
PSORS1C2 psoriasis susceptibility 1 candidate 2 0.811695
MICE MHC class I polypeptide-related sequence E (pseudogene) 0.732696
CPLX1 complexin 1 0.682395
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D 0.630491
DDR1 discoidin domain receptor tyrosine kinase 1 0.619616
DPCR1 diffuse panbronchiolitis critical region 1 0.607204
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.536598
MCCD1 mitochondrial coiled-coil domain 1 0.5104
LTA lymphotoxin alpha 0.458993
HCG18 HLA complex group 18 (non-protein coding) 0.452799
HCG9 HLA complex group 9 (non-protein coding) 0.441591
TRIM26 tripartite motif containing 26 0.420382
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 0.41901
HLA-E major histocompatibility complex, class I, E 0.367101
FOXP1 forkhead box P1 0.366153
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 0.345537
VARS2 valyl-tRNA synthetase 2, mitochondrial 0.343596
LACC1 laccase (multicopper oxidoreductase) domain containing 1 0.318692
HLA-F major histocompatibility complex, class I, F 0.316391
SFTA2 surfactant associated 2 0.31538
GPM6A glycoprotein M6A 0.27937
POU5F1 POU class 5 homeobox 1 0.278987
CSMD1 CUB and Sushi multiple domains 1 0.269404
MICB MHC class I polypeptide-related sequence B 0.251651
FBXL2 F-box and leucine-rich repeat protein 2 0.238356
WASF5P WAS protein family, member 5, pseudogene 0.232936
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 0.223125
MICD MHC class I polypeptide-related sequence D (pseudogene) 0.201758
UBP1 upstream binding protein 1 (LBP-1a) 0.201065
CLASP2 cytoplasmic linker associated protein 2 0.200485
WDFY4 WDFY family member 4 0.199407
MCF2L2 MCF.2 cell line derived transforming sequence-like 2 0.190379
PPIAP9 peptidylprolyl isomerase A (cyclophilin A) pseudogene 9 0.189351
STAT4 signal transducer and activator of transcription 4 0.18321
EFCAB11 EF-hand calcium binding domain 11 0.171181
PPP1R10 protein phosphatase 1, regulatory subunit 10 0.16878
MDC1 mediator of DNA-damage checkpoint 1 0.168394
JARID2 jumonji, AT rich interactive domain 2 0.158585
PHTF2 putative homeodomain transcription factor 2 0.14802
IL1R2 interleukin 1 receptor, type II 0.145589
WWTR1 WW domain containing transcription regulator 1 0.138345
CCDC42 coiled-coil domain containing 42 0.118979
ACSBG1 acyl-CoA synthetase bubblegum family member 1 0.082108
FXYD5 FXYD domain containing ion transport regulator 5 0.081618
FYCO1 FYVE and coiled-coil domain containing 1 0.076954
ILDR1 immunoglobulin-like domain containing receptor 1 0.074273
CDHR3 cadherin-related family member 3 0.071925
CDSN corneodesmosin 0.06609
TCF19 transcription factor 19 0.058964