| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belinostat perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belinostat_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.147914 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.116772 |
| CANX | calnexin | 0.0843568 |
| LOX | lysyl oxidase | 0.0791264 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0760906 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0732181 |
| FBN1 | fibrillin 1 | 0.0697966 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0647472 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0626855 |
| COL5A2 | collagen, type V, alpha 2 | 0.0615043 |
| SLC39A11 | solute carrier family 39, member 11 | 0.060748 |
| LOXL2 | lysyl oxidase-like 2 | 0.0585412 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0549991 |
| NAV1 | neuron navigator 1 | 0.0523173 |
| AHNAK | AHNAK nucleoprotein | 0.0516549 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0515248 |
| AUTS2 | autism susceptibility candidate 2 | 0.0481999 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0455963 |
| SEPTIN9 | septin 9 | 0.045411 |
| THBS2 | thrombospondin 2 | 0.0448706 |
| COPA | coatomer protein complex, subunit alpha | 0.0418483 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0394799 |
| COL5A1 | collagen, type V, alpha 1 | 0.0390632 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0360495 |
| OGA | O-GlcNAcase | 0.0348581 |
| APP | amyloid beta (A4) precursor protein | 0.0346492 |
| HDAC9 | histone deacetylase 9 | 0.0340997 |
| ANXA2 | annexin A2 | 0.0339258 |
| MAP1B | microtubule-associated protein 1B | 0.0330611 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0328476 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.032778 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0318792 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0317617 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0311413 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.03112 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0310149 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0309723 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0309432 |
| TPM4 | tropomyosin 4 | 0.0308954 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0305876 |
| CDH13 | cadherin 13 | 0.0304414 |
| DST | dystonin | 0.0304395 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0302814 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0302756 |
| EGFR | epidermal growth factor receptor | 0.0287523 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0284923 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0284249 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0277213 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0272783 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0259043 |
| YEATS2 | YEATS domain containing 2 | 0.0258993 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0257954 |
| ITSN2 | intersectin 2 | 0.025738 |
| GOLGA2 | golgin A2 | 0.0255485 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0253521 |
| FNIP1 | folliculin interacting protein 1 | 0.025286 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0248177 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0247061 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0246931 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.0244736 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0242112 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0241162 |
| SBF2 | SET binding factor 2 | 0.0240899 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0238875 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0238651 |
| PODXL | podocalyxin-like | 0.0237258 |
| NAV2 | neuron navigator 2 | 0.0234244 |
| MSI2 | musashi RNA-binding protein 2 | 0.0224698 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0224431 |
| DSPP | dentin sialophosphoprotein | 0.0221786 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0219927 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0219542 |
| FBXO11 | F-box protein 11 | 0.021786 |
| VEGFC | vascular endothelial growth factor C | 0.021674 |
| HDLBP | high density lipoprotein binding protein | 0.0215517 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0215251 |
| SP3 | Sp3 transcription factor | 0.0214248 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0213865 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0213414 |
| C1D | C1D nuclear receptor corepressor | 0.0208375 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0204722 |
| GPC6 | glypican 6 | 0.0201076 |
| SUCO | SUN domain containing ossification factor | 0.0200728 |
| RSF1 | remodeling and spacing factor 1 | 0.0200688 |
| AFDN | afadin, adherens junction formation factor | 0.0200672 |
| SFTPA2 | surfactant protein A2 | 0.0200369 |
| ANO6 | anoctamin 6 | 0.0200323 |
| LDHA | lactate dehydrogenase A | 0.0198953 |
| NCKAP1 | NCK-associated protein 1 | 0.0193858 |
| DSCAM | Down syndrome cell adhesion molecule | 0.019029 |
| MSN | moesin | 0.0189313 |
| EHBP1 | EH domain binding protein 1 | 0.0186721 |
| MAP4 | microtubule-associated protein 4 | 0.0184796 |
| PRELID2 | PRELI domain containing 2 | 0.0184473 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0181888 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.0180873 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0180812 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0180211 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0179313 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0178829 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.194087 |
| MT2A | metallothionein 2A | -0.138573 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.128388 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.112689 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0532574 |
| PTMA | prothymosin, alpha | -0.0486556 |
| S100A10 | S100 calcium binding protein A10 | -0.046078 |
| LMNA | lamin A/C | -0.0456865 |
| NDRG1 | N-myc downstream regulated 1 | -0.044344 |
| VIM | vimentin | -0.0432221 |
| MT1X | metallothionein 1X | -0.0431281 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0428505 |
| RPS6 | ribosomal protein S6 | -0.042651 |
| RPL35A | ribosomal protein L35a | -0.0409217 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0400898 |
| RPL23 | ribosomal protein L23 | -0.0388604 |
| CD44 | CD44 molecule (Indian blood group) | -0.0371211 |
| RPLP2 | ribosomal protein, large, P2 | -0.036312 |
| RPS19 | ribosomal protein S19 | -0.0354851 |
| RPL36 | ribosomal protein L36 | -0.0346155 |
| ACTG1 | actin gamma 1 | -0.0334586 |
| RPL28 | ribosomal protein L28 | -0.0330999 |
| RPLP1 | ribosomal protein, large, P1 | -0.0328521 |
| HLA-B | major histocompatibility complex, class I, B | -0.0318757 |
| CAVIN1 | caveolae associated protein 1 | -0.0314267 |
| STC1 | stanniocalcin 1 | -0.0310493 |
| RPS8 | ribosomal protein S8 | -0.0308343 |
| RPL37A | ribosomal protein L37a | -0.0302788 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0297313 |
| RPS24 | ribosomal protein S24 | -0.0293905 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0292993 |
| LOC112694756 | uncharaterized LOC112694756 | -0.028392 |
| RPL32 | ribosomal protein L32 | -0.0281041 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0276516 |
| RPS3 | ribosomal protein S3 | -0.0274515 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0269074 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0262634 |
| RPL12 | ribosomal protein L12 | -0.0260897 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0260349 |
| RPL26 | ribosomal protein L26 | -0.0254993 |
| RPL31 | ribosomal protein L31 | -0.0243803 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0240907 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0240417 |
| RPL34 | ribosomal protein L34 | -0.0234648 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0231972 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0228763 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0227004 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0223681 |
| FTL | ferritin, light polypeptide | -0.0222121 |
| SEC61G | Sec61 gamma subunit | -0.0222011 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.022076 |
| RPS15 | ribosomal protein S15 | -0.021902 |
| FAM162A | family with sequence similarity 162, member A | -0.0218775 |
| PKM | pyruvate kinase, muscle | -0.0217064 |
| RPS12 | ribosomal protein S12 | -0.0215398 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0207161 |
| H3-3B | H3.3 histone B | -0.0204971 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0203332 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0202182 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0199042 |
| POTEF | POTE ankyrin domain family, member F | -0.0196666 |
| RPL35 | ribosomal protein L35 | -0.019599 |
| RPS21 | ribosomal protein S21 | -0.0195944 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0189691 |
| RPL19 | ribosomal protein L19 | -0.0187219 |
| RPL9 | ribosomal protein L9 | -0.0186856 |
| RPS14 | ribosomal protein S14 | -0.0186668 |
| S100A4 | S100 calcium binding protein A4 | -0.0185328 |
| RPS16 | ribosomal protein S16 | -0.0182885 |
| S100A6 | S100 calcium binding protein A6 | -0.0181599 |
| RPL38 | ribosomal protein L38 | -0.0178995 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0167143 |
| RPLP0 | ribosomal protein, large, P0 | -0.0166748 |
| RPL27A | ribosomal protein L27a | -0.0163626 |
| RPS23 | ribosomal protein S23 | -0.0161916 |
| TXNRD1 | thioredoxin reductase 1 | -0.0160327 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | -0.0160116 |
| JPT1 | Jupiter microtubule associated homolog 1 | -0.0157331 |
| PRDX1 | peroxiredoxin 1 | -0.0156486 |
| SDC4 | syndecan 4 | -0.0156232 |
| HMGB1 | high mobility group box 1 | -0.0155862 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0155268 |
| SERF2 | small EDRK-rich factor 2 | -0.0154605 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0153017 |
| RACK1 | receptor for activated C kinase 1 | -0.0152216 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0152144 |
| RPL27 | ribosomal protein L27 | -0.0150931 |
| IER3 | immediate early response 3 | -0.0150484 |
| RPS27A | ribosomal protein S27a | -0.0150188 |
| BSG | basigin (Ok blood group) | -0.0147917 |
| EGR1 | early growth response 1 | -0.0147287 |
| CD81 | CD81 molecule | -0.0147227 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0147171 |
| PFN1 | profilin 1 | -0.0146978 |
| GABARAPL2 | GABA(A) receptor-associated protein-like 2 | -0.0146427 |
| RPS29 | ribosomal protein S29 | -0.0145361 |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | -0.0143007 |
| RPL11 | ribosomal protein L11 | -0.0142292 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0140704 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0139978 |
