| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belinostat perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belinostat_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.133141 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0945785 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0748411 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0729806 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0480324 |
| ANXA1 | annexin A1 | 0.0462188 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0455988 |
| PCBP2 | poly(rC) binding protein 2 | 0.0440498 |
| YBX1 | Y box binding protein 1 | 0.0406439 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0362508 |
| KIF5B | kinesin family member 5B | 0.0359507 |
| CPOX | coproporphyrinogen oxidase | 0.035183 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0351606 |
| RPS2 | ribosomal protein S2 | 0.0340276 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0325066 |
| TPI1 | triosephosphate isomerase 1 | 0.0323915 |
| YBX3 | Y box binding protein 3 | 0.0314551 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0299996 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0289935 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0289326 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0281844 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0252731 |
| KLHL24 | kelch-like family member 24 | 0.0251809 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0251595 |
| NCKAP1 | NCK-associated protein 1 | 0.0250213 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0247847 |
| TPR | translocated promoter region, nuclear basket protein | 0.024135 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0219981 |
| MEMO1 | mediator of cell motility 1 | 0.0205795 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0199831 |
| ZNF292 | zinc finger protein 292 | 0.0198841 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.0198248 |
| PCM1 | pericentriolar material 1 | 0.0197069 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0196585 |
| PLK2 | polo-like kinase 2 | 0.0193574 |
| OGA | O-GlcNAcase | 0.0193201 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0192643 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0191702 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0189635 |
| CCNL1 | cyclin L1 | 0.0189449 |
| NEK7 | NIMA-related kinase 7 | 0.0188787 |
| RPL12 | ribosomal protein L12 | 0.0187615 |
| MED13L | mediator complex subunit 13-like | 0.018736 |
| NCOR1 | nuclear receptor corepressor 1 | 0.018615 |
| EDN1 | endothelin 1 | 0.018491 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.018456 |
| RPL26 | ribosomal protein L26 | 0.0178137 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0176961 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0176808 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0175449 |
| HMGB2 | high mobility group box 2 | 0.0174392 |
| SERINC1 | serine incorporator 1 | 0.0174046 |
| HSPA4 | heat shock 70kDa protein 4 | 0.017321 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.017187 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0171605 |
| DSPP | dentin sialophosphoprotein | 0.0170834 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0169928 |
| PHF21A | PHD finger protein 21A | 0.0169899 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0169805 |
| CLDND1 | claudin domain containing 1 | 0.0168729 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0168271 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0168107 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0167987 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0166967 |
| ARRDC3 | arrestin domain containing 3 | 0.0166228 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0165257 |
| RPL7 | ribosomal protein L7 | 0.0163536 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0162934 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0161239 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0159177 |
| USP53 | ubiquitin specific peptidase 53 | 0.0158203 |
| RLF | rearranged L-myc fusion | 0.0157834 |
| SPAG9 | sperm associated antigen 9 | 0.0156538 |
| RPL13A | ribosomal protein L13a | 0.0156215 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0155354 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | 0.0154299 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0154039 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0152849 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0152664 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0152563 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0150969 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0149606 |
| RPLP0 | ribosomal protein, large, P0 | 0.0146281 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0146053 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0145576 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0145375 |
| YEATS2 | YEATS domain containing 2 | 0.0145302 |
| LPIN2 | lipin 2 | 0.0144704 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0144521 |
| FBXO11 | F-box protein 11 | 0.0143206 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.014276 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | 0.0142362 |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 | 0.01423 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0140711 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0139413 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0139404 |
| SFTPA2 | surfactant protein A2 | 0.0139356 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0138818 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0138652 |
| YTHDC1 | YTH domain containing 1 | 0.0137895 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.140578 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.127427 |
| NLGN1 | neuroligin 1 | -0.122751 |
| HMGA2 | high mobility group AT-hook 2 | -0.0783884 |
| VIM | vimentin | -0.0750519 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0725883 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0652336 |
| YAP1 | Yes-associated protein 1 | -0.0580059 |
| MMP12 | matrix metallopeptidase 12 | -0.05454 |
| ACTG1 | actin gamma 1 | -0.0537749 |
| NHSL1 | NHS-like 1 | -0.0524309 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.048273 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0465276 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0447427 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0402726 |
| EGR1 | early growth response 1 | -0.0397688 |
| RPL35A | ribosomal protein L35a | -0.0389461 |
| JMJD1C | jumonji domain containing 1C | -0.0376718 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0361564 |
| RASAL2 | RAS protein activator like 2 | -0.034428 |
| CMIP | c-Maf inducing protein | -0.0341154 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0339534 |
| ZNF804A | zinc finger protein 804A | -0.033224 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | -0.0315618 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0315026 |
| CUX1 | cut-like homeobox 1 | -0.0305456 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0299149 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0287204 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.027838 |
| RPS19 | ribosomal protein S19 | -0.0278209 |
| EDARADD | EDAR-associated death domain | -0.0276657 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0273461 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.027261 |
| PCDH7 | protocadherin 7 | -0.0271937 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0268975 |
| PDGFC | platelet derived growth factor C | -0.0263916 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0251788 |
| EHBP1 | EH domain binding protein 1 | -0.0248854 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0242698 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0230961 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0228861 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0220271 |
| BCHE | butyrylcholinesterase | -0.0216597 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.0215915 |
| MKI67 | marker of proliferation Ki-67 | -0.0210974 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0206437 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.020422 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0203921 |
| NEBL | nebulette | -0.020102 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0198819 |
| KIF18B | kinesin family member 18B | -0.0198115 |
| NAV3 | neuron navigator 3 | -0.0196758 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0191472 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0185055 |
| PFN1 | profilin 1 | -0.0183785 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0181045 |
| VCL | vinculin | -0.0180601 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0178679 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0178374 |
| CEP112 | centrosomal protein 112kDa | -0.0178364 |
| RPL37A | ribosomal protein L37a | -0.0177245 |
| TUBA1B | tubulin, alpha 1b | -0.0174578 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0173185 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0172525 |
| S100A10 | S100 calcium binding protein A10 | -0.0171858 |
| EGFR | epidermal growth factor receptor | -0.0170002 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0169705 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | -0.0166009 |
| DIAPH2 | diaphanous-related formin 2 | -0.0165432 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0164375 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0161115 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0160993 |
| OSMR | oncostatin M receptor | -0.016044 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0158561 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0158242 |
| R3HDM2 | R3H domain containing 2 | -0.0157948 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0154703 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0154282 |
| COMMD10 | COMM domain containing 10 | -0.0152842 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0151826 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0151045 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0150337 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0149011 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0145996 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0145696 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.014419 |
| ETV6 | ets variant 6 | -0.014391 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0142792 |
| MAP1B | microtubule-associated protein 1B | -0.014048 |
| RSU1 | Ras suppressor protein 1 | -0.0140311 |
| SETX | senataxin | -0.0139909 |
| MTAP | methylthioadenosine phosphorylase | -0.0139888 |
| CENPF | centromere protein F, 350/400kDa | -0.0138264 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.013793 |
| RPS6 | ribosomal protein S6 | -0.0136889 |
| BRD4 | bromodomain containing 4 | -0.0136533 |
| AK1 | adenylate kinase 1 | -0.0134935 |
| HMGA1 | high mobility group AT-hook 1 | -0.0134195 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0134107 |
| CDK6 | cyclin-dependent kinase 6 | -0.013382 |
