| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belinostat perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belinostat_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.394014 |
| NDRG1 | N-myc downstream regulated 1 | 0.16288 |
| VEGFA | vascular endothelial growth factor A | 0.144241 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.13068 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0869612 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0816586 |
| CALR | calreticulin | 0.0751572 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0691858 |
| CANX | calnexin | 0.0581904 |
| LDHA | lactate dehydrogenase A | 0.0555344 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0476991 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0470814 |
| PDE10A | phosphodiesterase 10A | 0.0461518 |
| CADM1 | cell adhesion molecule 1 | 0.0461391 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0443568 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.043369 |
| ARRDC3 | arrestin domain containing 3 | 0.0430765 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0421949 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0418218 |
| LOXL2 | lysyl oxidase-like 2 | 0.0414759 |
| MRTFA | myocardin related transcription factor A | 0.0402719 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.040131 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0391715 |
| PCBP2 | poly(rC) binding protein 2 | 0.038976 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0386773 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0382934 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0379064 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0372164 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0370709 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0370547 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0368768 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.036308 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0357229 |
| ATP13A3 | ATPase type 13A3 | 0.0353962 |
| GOLGA4 | golgin A4 | 0.0351145 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0349534 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0348207 |
| SPAG9 | sperm associated antigen 9 | 0.034717 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0341932 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0333047 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0328172 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0309379 |
| POSTN | periostin, osteoblast specific factor | 0.0306511 |
| TFG | TRK-fused gene | 0.0299665 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0299108 |
| COPA | coatomer protein complex, subunit alpha | 0.0297853 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0288481 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0285792 |
| AXL | AXL receptor tyrosine kinase | 0.028119 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0279318 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0279043 |
| CD109 | CD109 molecule | 0.0278622 |
| TRAM1 | translocation associated membrane protein 1 | 0.0272349 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0271591 |
| KIF1B | kinesin family member 1B | 0.0267221 |
| LOX | lysyl oxidase | 0.0266358 |
| SQLE | squalene epoxidase | 0.0266112 |
| HMGA2 | high mobility group AT-hook 2 | 0.0257675 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0254944 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0254446 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0252788 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0250123 |
| SUCO | SUN domain containing ossification factor | 0.0249173 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0245095 |
| SETD5 | SET domain containing 5 | 0.0242869 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0242619 |
| FAT1 | FAT atypical cadherin 1 | 0.0240856 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0239715 |
| NBAS | neuroblastoma amplified sequence | 0.0238294 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0237187 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0237181 |
| WASF2 | WAS protein family, member 2 | 0.0235915 |
| MLF1 | myeloid leukemia factor 1 | 0.0235485 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0234862 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.023427 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0233341 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0227093 |
| GRB10 | growth factor receptor-bound protein 10 | 0.022689 |
| OGA | O-GlcNAcase | 0.0224477 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0224133 |
| PLEC | plectin | 0.0221148 |
| ZNF292 | zinc finger protein 292 | 0.0220984 |
| HIP1 | huntingtin interacting protein 1 | 0.0220424 |
| RNF145 | ring finger protein 145 | 0.0219614 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.021624 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0213964 |
| MSN | moesin | 0.021351 |
| BBX | bobby sox homolog (Drosophila) | 0.0213193 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.021283 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0212679 |
| HELZ | helicase with zinc finger | 0.0211942 |
| ADM | adrenomedullin | 0.0211181 |
| FOXJ3 | forkhead box J3 | 0.0211076 |
| TPM3 | tropomyosin 3 | 0.0207986 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0206698 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0205687 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0204108 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0201966 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0199447 |
| NOTCH2 | notch 2 | 0.0198773 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL1A1 | collagen, type I, alpha 1 | -0.231533 |
| VIM | vimentin | -0.119493 |
| CDH13 | cadherin 13 | -0.0959275 |
| IER3 | immediate early response 3 | -0.0789528 |
| ASPH | aspartate beta-hydroxylase | -0.0713843 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0691298 |
| ACTG1 | actin gamma 1 | -0.0684771 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0637299 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0603235 |
| CD44 | CD44 molecule (Indian blood group) | -0.0577242 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0545735 |
| COL5A1 | collagen, type V, alpha 1 | -0.0518615 |
| TMSB10 | thymosin beta 10 | -0.0516592 |
| RPS6 | ribosomal protein S6 | -0.0511882 |
| CAVIN1 | caveolae associated protein 1 | -0.0492153 |
| CALD1 | caldesmon 1 | -0.0482461 |
| COL1A2 | collagen, type I, alpha 2 | -0.0478674 |
| RPL35A | ribosomal protein L35a | -0.0472176 |
| RPS8 | ribosomal protein S8 | -0.039784 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0390599 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.037099 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.036431 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0361339 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.034879 |
| GLIS3 | GLIS family zinc finger 3 | -0.0347453 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.034524 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0331552 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0317631 |
| RPS24 | ribosomal protein S24 | -0.0309022 |
| RPS3 | ribosomal protein S3 | -0.0295273 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0294607 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0293704 |
| TMSB4X | thymosin beta 4, X-linked | -0.028878 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0272842 |
| CNTN5 | contactin 5 | -0.0269144 |
| NAV1 | neuron navigator 1 | -0.0265832 |
| INHBA | inhibin, beta A | -0.0262519 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0257073 |
| RPL26 | ribosomal protein L26 | -0.0254601 |
| FOXP1 | forkhead box P1 | -0.0254144 |
| RPL28 | ribosomal protein L28 | -0.0253598 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.02531 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0247106 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0246693 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0245693 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.023433 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.023023 |
| RPLP1 | ribosomal protein, large, P1 | -0.0230082 |
| DST | dystonin | -0.0228683 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0228046 |
| NEK10 | NIMA-related kinase 10 | -0.0224709 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0222711 |
| RPS20 | ribosomal protein S20 | -0.022086 |
| RUNX1 | runt-related transcription factor 1 | -0.0220257 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0215995 |
| RPL23 | ribosomal protein L23 | -0.0213053 |
| RPL34 | ribosomal protein L34 | -0.0211848 |
| FRMD4A | FERM domain containing 4A | -0.0207539 |
| VCL | vinculin | -0.0207143 |
| PRSS23 | protease, serine, 23 | -0.0201452 |
| NREP | neuronal regeneration related protein | -0.0199055 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0197843 |
| IL6ST | interleukin 6 signal transducer | -0.0194573 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0193293 |
| RPS10 | ribosomal protein S10 | -0.0192239 |
| RPL36 | ribosomal protein L36 | -0.0188195 |
| SMYD3 | SET and MYND domain containing 3 | -0.0188022 |
| RPL11 | ribosomal protein L11 | -0.0187326 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.0185766 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 | -0.0185593 |
| RPS21 | ribosomal protein S21 | -0.0183816 |
| RPL38 | ribosomal protein L38 | -0.0182983 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0179362 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0177667 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0177445 |
| NRP1 | neuropilin 1 | -0.0177441 |
| RPS15 | ribosomal protein S15 | -0.0176022 |
| RPL8 | ribosomal protein L8 | -0.0175792 |
| HLA-B | major histocompatibility complex, class I, B | -0.0174731 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0173559 |
| OSMR | oncostatin M receptor | -0.0172797 |
| LAMC2 | laminin, gamma 2 | -0.0172721 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0169592 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0169552 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0168927 |
| RPL27 | ribosomal protein L27 | -0.0168401 |
| KHSRP | KH-type splicing regulatory protein | -0.0167629 |
| RPL37 | ribosomal protein L37 | -0.0165864 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0164863 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0163151 |
| CUX1 | cut-like homeobox 1 | -0.0162845 |
| RPL9 | ribosomal protein L9 | -0.0162745 |
| THY1 | Thy-1 cell surface antigen | -0.016243 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0161758 |
| RPL18 | ribosomal protein L18 | -0.0160879 |
| AHNAK | AHNAK nucleoprotein | -0.0158962 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0158898 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0158555 |
| RPL19 | ribosomal protein L19 | -0.0158324 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0158181 |
