| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belinostat perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belinostat_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0861347 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0856688 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0671587 |
| RAI1 | retinoic acid induced 1 | 0.0629889 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0584538 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0533827 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0531832 |
| TP63 | tumor protein p63 | 0.0530043 |
| CANX | calnexin | 0.0524856 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0493019 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0479141 |
| PYGL | phosphorylase, glycogen, liver | 0.0473189 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0463794 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0461058 |
| RAD51B | RAD51 paralog B | 0.0451446 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0451319 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0448631 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0442095 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0432811 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.041394 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0412784 |
| LOXL2 | lysyl oxidase-like 2 | 0.0410586 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0404483 |
| HDAC9 | histone deacetylase 9 | 0.0402541 |
| SLK | STE20-like kinase | 0.0383917 |
| PDE10A | phosphodiesterase 10A | 0.0377703 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0359687 |
| YEATS2 | YEATS domain containing 2 | 0.0359464 |
| EXOC4 | exocyst complex component 4 | 0.034856 |
| EHBP1 | EH domain binding protein 1 | 0.034788 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0345966 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0345609 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0341305 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0327137 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0326994 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0323377 |
| TPM4 | tropomyosin 4 | 0.0316036 |
| NHSL1 | NHS-like 1 | 0.0311131 |
| EFNA5 | ephrin-A5 | 0.0305006 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0297695 |
| PTMA | prothymosin, alpha | 0.0294128 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.029204 |
| SFTPA2 | surfactant protein A2 | 0.0286915 |
| RIGI | RNA sensor RIG-I | 0.0281406 |
| RAP2B | RAP2B, member of RAS oncogene family | 0.0274477 |
| VASP | vasodilator-stimulated phosphoprotein | 0.0268233 |
| RPS2 | ribosomal protein S2 | 0.0264747 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.026351 |
| FBXO11 | F-box protein 11 | 0.026148 |
| UBXN4 | UBX domain protein 4 | 0.0260287 |
| RPL12 | ribosomal protein L12 | 0.0257815 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0256814 |
| RNF213 | ring finger protein 213 | 0.0254635 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0253633 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0253363 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0251699 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0247446 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.024492 |
| RUNX1 | runt-related transcription factor 1 | 0.0243584 |
| CENPF | centromere protein F, 350/400kDa | 0.0240061 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0236372 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.023541 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0233977 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0229179 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0226353 |
| NAV2 | neuron navigator 2 | 0.0223098 |
| RREB1 | ras responsive element binding protein 1 | 0.0220497 |
| TNS3 | tensin 3 | 0.0219118 |
| KLHL24 | kelch-like family member 24 | 0.0219079 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.0215174 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0214057 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.021296 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0212362 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0209482 |
| PATJ | PATJ crumbs cell polarity complex component | 0.020929 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0207063 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0206866 |
| PTK2 | protein tyrosine kinase 2 | 0.0206068 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.020373 |
| EPHA4 | EPH receptor A4 | 0.0201787 |
| CUX1 | cut-like homeobox 1 | 0.0201695 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0201379 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0200958 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | 0.0195497 |
| ERBIN | erbb2 interacting protein | 0.0192921 |
| SEC24A | SEC24 family member A | 0.0192856 |
| GOLGA4 | golgin A4 | 0.0190245 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0187854 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0185731 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0185652 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0184343 |
| MEF2A | myocyte enhancer factor 2A | 0.018345 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0183306 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0181218 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.017986 |
| MYOF | myoferlin | 0.0178915 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0178244 |
| CD109 | CD109 molecule | 0.0176942 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.0176765 |
| PMP22 | peripheral myelin protein 22 | 0.0175905 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.268028 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.223562 |
| TMSB10 | thymosin beta 10 | -0.188304 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.163977 |
| UBC | ubiquitin C | -0.143843 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.116549 |
| MT2A | metallothionein 2A | -0.10841 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0926345 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0861719 |
| AHNAK | AHNAK nucleoprotein | -0.0736978 |
| RPS27A | ribosomal protein S27a | -0.073597 |
| CD44 | CD44 molecule (Indian blood group) | -0.0726424 |
| JUN | jun proto-oncogene | -0.0714601 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0662927 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0634725 |
| TXNRD1 | thioredoxin reductase 1 | -0.0628425 |
| MT1X | metallothionein 1X | -0.0594946 |
| ACTG1 | actin gamma 1 | -0.0586787 |
| EZR | ezrin | -0.0576736 |
| EREG | epiregulin | -0.0554745 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0544555 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0544478 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0538109 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0536294 |
| ENO1 | enolase 1, (alpha) | -0.0517523 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0503371 |
| EMP1 | epithelial membrane protein 1 | -0.0463248 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0411098 |
| SDC4 | syndecan 4 | -0.0388919 |
| RPL23 | ribosomal protein L23 | -0.0373216 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0353815 |
| POTEF | POTE ankyrin domain family, member F | -0.0353335 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0340024 |
| S100A6 | S100 calcium binding protein A6 | -0.0329989 |
| RPL4 | ribosomal protein L4 | -0.0324937 |
| RTN4 | reticulon 4 | -0.0320541 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0306561 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0306395 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0304447 |
| RBM25 | RNA binding motif protein 25 | -0.0295057 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0294092 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0290436 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0287295 |
| RBM39 | RNA binding motif protein 39 | -0.0284249 |
| MT1E | metallothionein 1E | -0.0283264 |
| RPS12 | ribosomal protein S12 | -0.0279829 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0274722 |
| VMP1 | vacuole membrane protein 1 | -0.0272136 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0254759 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0254114 |
| RPS24 | ribosomal protein S24 | -0.0253444 |
| SPAG9 | sperm associated antigen 9 | -0.0250638 |
| PKM | pyruvate kinase, muscle | -0.0248345 |
| RPS4X | ribosomal protein S4, X-linked | -0.0243255 |
| LDHA | lactate dehydrogenase A | -0.024275 |
| MATR3 | matrin 3 | -0.024214 |
| TMEM41B | transmembrane protein 41B | -0.0230517 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0228399 |
| TYW1B | tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) | -0.0227624 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0225463 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0225406 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0223646 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0223126 |
| TNPO1 | transportin 1 | -0.0222782 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0221206 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0218405 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0217182 |
| IPO7 | importin 7 | -0.0216107 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0212859 |
| SEPTIN2 | septin 2 | -0.0209061 |
| PRRC2C | proline-rich coiled-coil 2C | -0.020349 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0200663 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0199865 |
| RHOA | ras homolog family member A | -0.0197897 |
| KHSRP | KH-type splicing regulatory protein | -0.0197261 |
| S100A10 | S100 calcium binding protein A10 | -0.0196615 |
| BLTP2 | bridge-like lipid transfer protein family member 2 | -0.0195742 |
| RPL7A | ribosomal protein L7a | -0.0192058 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0192015 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0191839 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0191416 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | -0.0190364 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.018794 |
| HMGB2 | high mobility group box 2 | -0.018596 |
| PGK1 | phosphoglycerate kinase 1 | -0.0185936 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0185052 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0184694 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0182639 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0182136 |
| TOP1 | topoisomerase (DNA) I | -0.0182015 |
| DENND5A | DENN/MADD domain containing 5A | -0.0181675 |
| RHEB | Ras homolog enriched in brain | -0.0179764 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0178552 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0178369 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0176271 |
| OGA | O-GlcNAcase | -0.0176233 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0176014 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0175556 |
| KLF6 | Kruppel-like factor 6 | -0.0174106 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0171299 |
