| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belinostat perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belinostat_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EGFR | epidermal growth factor receptor | 0.196348 |
| INTS6 | integrator complex subunit 6 | 0.085564 |
| CANX | calnexin | 0.0775842 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0720884 |
| HDLBP | high density lipoprotein binding protein | 0.0684861 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0655271 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0647824 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0587073 |
| LMO7 | LIM domain 7 | 0.0579585 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0561896 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0558344 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0528633 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0478914 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0455664 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0447945 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.042379 |
| NGLY1 | N-glycanase 1 | 0.041376 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0411081 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0410192 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0397861 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0387569 |
| ANXA2 | annexin A2 | 0.0370356 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0366287 |
| AHNAK | AHNAK nucleoprotein | 0.0347157 |
| OGA | O-GlcNAcase | 0.0317455 |
| NSUN6 | NOP2/Sun domain family, member 6 | 0.0313085 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0309667 |
| CES1 | carboxylesterase 1 | 0.0306569 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0306087 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0304529 |
| PCBP2 | poly(rC) binding protein 2 | 0.0304204 |
| MCL1 | myeloid cell leukemia 1 | 0.0302467 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0301505 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0297395 |
| PLEC | plectin | 0.0296706 |
| GOLGB1 | golgin B1 | 0.02884 |
| WASF2 | WAS protein family, member 2 | 0.0277361 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0277112 |
| ABLIM1 | actin binding LIM protein 1 | 0.0275451 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0271448 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0262137 |
| NDE1 | nudE neurodevelopment protein 1 | 0.026107 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0254506 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0249372 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog | 0.0246501 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.024501 |
| HOMER1 | homer scaffolding protein 1 | 0.0244562 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0242208 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.024018 |
| PYGL | phosphorylase, glycogen, liver | 0.0233984 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0232906 |
| IRF1 | interferon regulatory factor 1 | 0.0229433 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0227917 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0226368 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0225347 |
| TRAPPC9 | trafficking protein particle complex 9 | 0.0224235 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.022405 |
| GOLGA3 | golgin A3 | 0.0220816 |
| ATXN1 | ataxin 1 | 0.0220696 |
| ARRDC3 | arrestin domain containing 3 | 0.021975 |
| HBP1 | HMG-box transcription factor 1 | 0.0217419 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0217246 |
| SQSTM1 | sequestosome 1 | 0.0214722 |
| KLHL24 | kelch-like family member 24 | 0.0213816 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.02129 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0209881 |
| CCNG2 | cyclin G2 | 0.0209124 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0208062 |
| AEBP2 | AE binding protein 2 | 0.0206897 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0203188 |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 | 0.0199145 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0195028 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0192806 |
| DSPP | dentin sialophosphoprotein | 0.0191648 |
| RLIM | ring finger protein, LIM domain interacting | 0.0191172 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like | 0.0189925 |
| ARCN1 | archain 1 | 0.0185408 |
| ZBTB1 | zinc finger and BTB domain containing 1 | 0.0184511 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0184498 |
| TMEM184B | transmembrane protein 184B | 0.0183416 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0183347 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0182664 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0179466 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0172855 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | 0.0172818 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0170789 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0168214 |
| GUK1 | guanylate kinase 1 | 0.0166924 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0166788 |
| RAP2B | RAP2B, member of RAS oncogene family | 0.0165818 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0162899 |
| CTBP2 | C-terminal binding protein 2 | 0.0161869 |
| GPATCH2L | G patch domain containing 2-like | 0.0160862 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0160813 |
| LYST | lysosomal trafficking regulator | 0.0158021 |
| FBXO11 | F-box protein 11 | 0.0157052 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0154867 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0152069 |
| GOLGA2 | golgin A2 | 0.0151261 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0151192 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.283044 |
| TMSB10 | thymosin beta 10 | -0.154008 |
| GRAMD1B | GRAM domain containing 1B | -0.0946058 |
| MT2A | metallothionein 2A | -0.0877746 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0771898 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.077035 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0766396 |
| CST3 | cystatin C | -0.0737839 |
| NDRG1 | N-myc downstream regulated 1 | -0.0722798 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0714346 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -0.0692009 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0616692 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0583096 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0557354 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0553509 |
| PKM | pyruvate kinase, muscle | -0.0510245 |
| SEC61G | Sec61 gamma subunit | -0.0504963 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0499939 |
| FTL | ferritin, light polypeptide | -0.0485078 |
| OSMR | oncostatin M receptor | -0.0477984 |
| RPL37A | ribosomal protein L37a | -0.047747 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0470488 |
| RPL35A | ribosomal protein L35a | -0.0460605 |
| RPS6 | ribosomal protein S6 | -0.0438462 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0434147 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0424078 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0423891 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0422059 |
| ACTG1 | actin gamma 1 | -0.0417763 |
| AREG | amphiregulin | -0.0391019 |
| RAB10 | RAB10, member RAS oncogene family | -0.0382601 |
| RPS3 | ribosomal protein S3 | -0.0380676 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0364522 |
| RPLP1 | ribosomal protein, large, P1 | -0.0363838 |
| LAMA4 | laminin, alpha 4 | -0.0353966 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0350242 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0348825 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0348534 |
| CCND1 | cyclin D1 | -0.0345358 |
| KRT7 | keratin 7, type II | -0.0345272 |
| RPS12 | ribosomal protein S12 | -0.0342936 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0337594 |
| GPHN | gephyrin | -0.0333691 |
| JMJD1C | jumonji domain containing 1C | -0.0330374 |
| DTNA | dystrobrevin, alpha | -0.0330066 |
| RPS25 | ribosomal protein S25 | -0.0328537 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0324971 |
| MYOF | myoferlin | -0.0316919 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0315833 |
| B2M | beta-2-microglobulin | -0.0314071 |
| S100A10 | S100 calcium binding protein A10 | -0.0310073 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.030894 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0303579 |
| LAMC2 | laminin, gamma 2 | -0.0302727 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0300838 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0300741 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0299119 |
| S100A9 | S100 calcium binding protein A9 | -0.0293201 |
| RPS24 | ribosomal protein S24 | -0.0292886 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0292039 |
| PRDX1 | peroxiredoxin 1 | -0.0291236 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0288689 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.0282201 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.028101 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0276162 |
| RBM39 | RNA binding motif protein 39 | -0.0273369 |
| RPS19 | ribosomal protein S19 | -0.0271318 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0267089 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.026303 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0259352 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0259024 |
| TNPO1 | transportin 1 | -0.025866 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0256597 |
| CDCP1 | CUB domain containing protein 1 | -0.025541 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0252371 |
| S100A11 | S100 calcium binding protein A11 | -0.0251893 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0248412 |
| RPLP2 | ribosomal protein, large, P2 | -0.0246005 |
| PUM2 | pumilio RNA-binding family member 2 | -0.024592 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0242688 |
| EGR1 | early growth response 1 | -0.0241354 |
| SMYD3 | SET and MYND domain containing 3 | -0.0240681 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0238504 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0236929 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0235959 |
| POTEF | POTE ankyrin domain family, member F | -0.023512 |
| SCEL | sciellin | -0.023191 |
| ZNF292 | zinc finger protein 292 | -0.0229874 |
| RPL31 | ribosomal protein L31 | -0.022772 |
| EFNA5 | ephrin-A5 | -0.0227003 |
| TOP1 | topoisomerase (DNA) I | -0.0226659 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0224847 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0223614 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0221443 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0221058 |
| IER3 | immediate early response 3 | -0.02191 |
| MED13L | mediator complex subunit 13-like | -0.0216917 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0215869 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | -0.0213169 |
| MATR3 | matrin 3 | -0.0212819 |
