| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belinostat perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belinostat_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SDK1 | sidekick cell adhesion molecule 1 | 0.141094 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.128728 |
| PCBP2 | poly(rC) binding protein 2 | 0.128481 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0987292 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0790523 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0771213 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0744284 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0696133 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0689252 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0668239 |
| CANX | calnexin | 0.0667176 |
| VIM | vimentin | 0.0648771 |
| FN1 | fibronectin 1 | 0.0614659 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0594571 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.055968 |
| CDH13 | cadherin 13 | 0.0550403 |
| FAM20C | family with sequence similarity 20, member C | 0.0515169 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0488819 |
| NAV2 | neuron navigator 2 | 0.0484272 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0452711 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0446681 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0443287 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0438447 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0436801 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0436755 |
| STC1 | stanniocalcin 1 | 0.0430479 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0429291 |
| ENO1 | enolase 1, (alpha) | 0.0426409 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0425918 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0421445 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0418883 |
| MTSS1 | metastasis suppressor 1 | 0.0418183 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0410681 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.041015 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0396502 |
| CALR | calreticulin | 0.0395522 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0392139 |
| SPAG9 | sperm associated antigen 9 | 0.0389201 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.038483 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0375395 |
| LDHA | lactate dehydrogenase A | 0.037402 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0361815 |
| SFTPA2 | surfactant protein A2 | 0.0361051 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0360222 |
| ATXN1 | ataxin 1 | 0.0359584 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.035608 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0351772 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0349 |
| INTS6 | integrator complex subunit 6 | 0.0348535 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0334316 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0328575 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0320953 |
| YBX1 | Y box binding protein 1 | 0.0311 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0310011 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0309478 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0306169 |
| SEPTIN9 | septin 9 | 0.0302041 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0301317 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0296181 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0295811 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0293283 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0292611 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0286753 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0286674 |
| MCL1 | myeloid cell leukemia 1 | 0.02826 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0281516 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0280865 |
| ASPH | aspartate beta-hydroxylase | 0.0277967 |
| RIOK3 | RIO kinase 3 | 0.0277427 |
| RAI1 | retinoic acid induced 1 | 0.0275567 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0272424 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0271215 |
| VEGFA | vascular endothelial growth factor A | 0.0267902 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0267539 |
| PTMA | prothymosin, alpha | 0.0266389 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0261071 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0260307 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0259869 |
| SQSTM1 | sequestosome 1 | 0.0258385 |
| RPLP0 | ribosomal protein, large, P0 | 0.0258209 |
| TGFB1 | transforming growth factor, beta 1 | 0.0257716 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0255929 |
| FAM107B | family with sequence similarity 107, member B | 0.0255625 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0254526 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0252603 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0251854 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0251699 |
| GOLGA4 | golgin A4 | 0.0251284 |
| APP | amyloid beta (A4) precursor protein | 0.0250451 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0248548 |
| HIP1 | huntingtin interacting protein 1 | 0.0247198 |
| EFNA5 | ephrin-A5 | 0.0242934 |
| COG5 | component of oligomeric golgi complex 5 | 0.0242276 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0238712 |
| RUNX1 | runt-related transcription factor 1 | 0.0237753 |
| LOX | lysyl oxidase | 0.023563 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0234324 |
| PTK2 | protein tyrosine kinase 2 | 0.0234161 |
| LOXL2 | lysyl oxidase-like 2 | 0.0234119 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0232573 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD44 | CD44 molecule (Indian blood group) | -0.106034 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0910193 |
| OSMR | oncostatin M receptor | -0.0741062 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0704077 |
| GLCCI1 | glucocorticoid induced 1 | -0.0544174 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0451079 |
| RAB27B | RAB27B, member RAS oncogene family | -0.045036 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0439878 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0393571 |
| KYNU | kynureninase | -0.0388235 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0335174 |
| ETV6 | ets variant 6 | -0.033022 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0326939 |
| NTN4 | netrin 4 | -0.0316695 |
| TMSB10 | thymosin beta 10 | -0.0312845 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0310872 |
| NRP1 | neuropilin 1 | -0.0303796 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0290351 |
| EGR1 | early growth response 1 | -0.0288142 |
| AOPEP | aminopeptidase O (putative) | -0.0287911 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0273878 |
| RBM39 | RNA binding motif protein 39 | -0.0266289 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0261849 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0257672 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0255102 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0253082 |
| IL1R1 | interleukin 1 receptor, type I | -0.0239404 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0232558 |
| ZNF385D | zinc finger protein 385D | -0.0225129 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0224762 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0200299 |
| IER3 | immediate early response 3 | -0.0193981 |
| ENOSF1 | enolase superfamily member 1 | -0.0192842 |
| RAD51B | RAD51 paralog B | -0.0191263 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0186037 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0184428 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0184358 |
| RUNX2 | runt-related transcription factor 2 | -0.0181961 |
| TMEM131 | transmembrane protein 131 | -0.0181102 |
| RNF24 | ring finger protein 24 | -0.0177841 |
| VRK2 | vaccinia related kinase 2 | -0.017457 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0174456 |
| TNNC1 | troponin C type 1 (slow) | -0.0173658 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0173238 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0170452 |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | -0.0170451 |
| KSR1 | kinase suppressor of ras 1 | -0.0169632 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0165831 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0162669 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0156389 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0155914 |
| RPL35A | ribosomal protein L35a | -0.0154807 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0154794 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0149299 |
| EPC1 | enhancer of polycomb homolog 1 (Drosophila) | -0.01482 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0144181 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.014248 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0140302 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0132114 |
| SYNJ2 | synaptojanin 2 | -0.0131675 |
| MX2 | MX dynamin-like GTPase 2 | -0.0131444 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.0130041 |
| CDK17 | cyclin-dependent kinase 17 | -0.0128489 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0127707 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0126599 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0126567 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0125465 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0124843 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0124795 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0122346 |
| GRAMD1B | GRAM domain containing 1B | -0.0121988 |
| EHBP1 | EH domain binding protein 1 | -0.0120869 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0119202 |
| FHL2 | four and a half LIM domains 2 | -0.0117141 |
| RAI14 | retinoic acid induced 14 | -0.0116936 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0116576 |
| CD58 | CD58 molecule | -0.0115565 |
| ATM | ATM serine/threonine kinase | -0.0115448 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0115116 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0112408 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0111788 |
| ATXN10 | ataxin 10 | -0.0110153 |
| ICA1 | islet cell autoantigen 1, 69kDa | -0.011013 |
| KLF6 | Kruppel-like factor 6 | -0.0109978 |
| RPS19 | ribosomal protein S19 | -0.0108827 |
| PHF14 | PHD finger protein 14 | -0.0108822 |
| ADD3 | adducin 3 (gamma) | -0.0108541 |
| EVA1C | eva-1 homolog C (C. elegans) | -0.010825 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0108024 |
| MEIS1 | Meis homeobox 1 | -0.0107177 |
| DCLK2 | doublecortin-like kinase 2 | -0.0106644 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0103553 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | -0.0102693 |
| EGFR | epidermal growth factor receptor | -0.0102392 |
| TMEM87A | transmembrane protein 87A | -0.0102295 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0102046 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0101825 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | -0.0101738 |
| DST | dystonin | -0.0101055 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0101036 |
