| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belinostat perturbation in NCI-H23 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belinostat_NCI-H23 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.203245 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.184877 |
| MCL1 | myeloid cell leukemia 1 | 0.136718 |
| YBX3 | Y box binding protein 3 | 0.106524 |
| PCBP2 | poly(rC) binding protein 2 | 0.080198 |
| EGR1 | early growth response 1 | 0.074183 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.07136 |
| RAD51B | RAD51 paralog B | 0.0658962 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.058922 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.055997 |
| CANX | calnexin | 0.0549114 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0520656 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0511202 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0509317 |
| TPM3 | tropomyosin 3 | 0.050363 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0498796 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0496798 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0483217 |
| BRD2 | bromodomain containing 2 | 0.0481595 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0472384 |
| TPI1 | triosephosphate isomerase 1 | 0.0449753 |
| GOLGB1 | golgin B1 | 0.0440317 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0439228 |
| BPTF | bromodomain PHD finger transcription factor | 0.0435034 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0434105 |
| RRM2 | ribonucleotide reductase M2 | 0.042863 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0419696 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0418087 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0415612 |
| EXOC4 | exocyst complex component 4 | 0.0409831 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0393795 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0389473 |
| STK4 | serine/threonine kinase 4 | 0.0386676 |
| COPA | coatomer protein complex, subunit alpha | 0.0384737 |
| CLTC | clathrin, heavy chain (Hc) | 0.0380043 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0373727 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0371101 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0362971 |
| NABP1 | nucleic acid binding protein 1 | 0.035269 |
| SETD5 | SET domain containing 5 | 0.0351664 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.0350227 |
| PYGL | phosphorylase, glycogen, liver | 0.0350043 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | 0.0348576 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0347795 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0347354 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0338549 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0334133 |
| ADIPOR2 | adiponectin receptor 2 | 0.0330826 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.033033 |
| CEP250 | centrosomal protein 250kDa | 0.0326571 |
| RSF1 | remodeling and spacing factor 1 | 0.0322902 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0320559 |
| ZNF638 | zinc finger protein 638 | 0.0318953 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0316935 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0315096 |
| PTK2 | protein tyrosine kinase 2 | 0.0308292 |
| STAG2 | stromal antigen 2 | 0.0305609 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0302772 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0301666 |
| HDGF | hepatoma-derived growth factor | 0.0300549 |
| UBC | ubiquitin C | 0.030049 |
| ADAR | adenosine deaminase, RNA-specific | 0.0299987 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0299803 |
| CDK19 | cyclin-dependent kinase 19 | 0.029661 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0296085 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0295833 |
| TPM4 | tropomyosin 4 | 0.0292145 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0290679 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.029016 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0289208 |
| MSN | moesin | 0.028907 |
| WDR70 | WD repeat domain 70 | 0.0287507 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0284672 |
| UBN2 | ubinuclein 2 | 0.0280822 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0280616 |
| ANO6 | anoctamin 6 | 0.0280222 |
| DENR | density-regulated protein | 0.0278244 |
| AFF3 | AF4/FMR2 family, member 3 | 0.027635 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0273604 |
| MKI67 | marker of proliferation Ki-67 | 0.0269299 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0266999 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0266756 |
| GDI2 | GDP dissociation inhibitor 2 | 0.026371 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0263671 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0261301 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0260463 |
| CCNL1 | cyclin L1 | 0.0259632 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0258539 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0256709 |
| DIAPH3 | diaphanous-related formin 3 | 0.0255445 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0252155 |
| JMJD1C | jumonji domain containing 1C | 0.0250747 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0249543 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0249104 |
| SFTPA2 | surfactant protein A2 | 0.0248135 |
| DSPP | dentin sialophosphoprotein | 0.0247032 |
| WASF2 | WAS protein family, member 2 | 0.0246943 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0246609 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0245931 |
| FNIP1 | folliculin interacting protein 1 | 0.0245468 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EIF5B | eukaryotic translation initiation factor 5B | -0.0896021 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0753101 |
| MT2A | metallothionein 2A | -0.0717674 |
| TMSB10 | thymosin beta 10 | -0.0676064 |
| PTMA | prothymosin, alpha | -0.0565387 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0534598 |
| RPS8 | ribosomal protein S8 | -0.051405 |
| RPLP1 | ribosomal protein, large, P1 | -0.0490902 |
| ATP11A | ATPase, class VI, type 11A | -0.047046 |
| CAVIN1 | caveolae associated protein 1 | -0.0466156 |
| RPS21 | ribosomal protein S21 | -0.045707 |
| RPL26 | ribosomal protein L26 | -0.0431847 |
| EFNA5 | ephrin-A5 | -0.0417564 |
| RPL38 | ribosomal protein L38 | -0.040873 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0386403 |
| RPL36 | ribosomal protein L36 | -0.0384333 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.038372 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0383193 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0378874 |
| VIM | vimentin | -0.0378224 |
| RPL35A | ribosomal protein L35a | -0.037558 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0375476 |
| RPL9 | ribosomal protein L9 | -0.0354478 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0351951 |
| RPL27 | ribosomal protein L27 | -0.0346482 |
| PDE10A | phosphodiesterase 10A | -0.0345989 |
| RPL12 | ribosomal protein L12 | -0.0341215 |
| TMEM165 | transmembrane protein 165 | -0.0338635 |
| HMGA1 | high mobility group AT-hook 1 | -0.0335719 |
| TOP1 | topoisomerase (DNA) I | -0.0332925 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.032272 |
| RPL18 | ribosomal protein L18 | -0.0321632 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0320738 |
| ACTG1 | actin gamma 1 | -0.0319614 |
| NPR2 | natriuretic peptide receptor 2 | -0.0316223 |
| PPM1L | protein phosphatase, Mg2+/Mn2+ dependent, 1L | -0.0309654 |
| NFIA | nuclear factor I/A | -0.0306749 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0306146 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0305192 |
| RPS27A | ribosomal protein S27a | -0.0302859 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0296906 |
| RPL23 | ribosomal protein L23 | -0.0293251 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0289639 |
| RNF38 | ring finger protein 38 | -0.0288957 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0285912 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0285911 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | -0.0282769 |
| RPS10 | ribosomal protein S10 | -0.0278284 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -0.0278178 |
| LDHB | lactate dehydrogenase B | -0.0277768 |
| HM13 | histocompatibility (minor) 13 | -0.0275527 |
| RPLP2 | ribosomal protein, large, P2 | -0.0275354 |
| SRSF11 | serine/arginine-rich splicing factor 11 | -0.0275041 |
| LMNA | lamin A/C | -0.0273442 |
| PPM1G | protein phosphatase, Mg2+/Mn2+ dependent, 1G | -0.0270941 |
| SMAD3 | SMAD family member 3 | -0.0269457 |
| NCOA7 | nuclear receptor coactivator 7 | -0.026768 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0264741 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0260772 |
| SSH2 | slingshot protein phosphatase 2 | -0.0258025 |
| RPL13A | ribosomal protein L13a | -0.0257995 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0257943 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0251835 |
| RPL34 | ribosomal protein L34 | -0.0251793 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0251267 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | -0.0249894 |
| RPS19 | ribosomal protein S19 | -0.0248882 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.0247122 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0243999 |
| S100A11 | S100 calcium binding protein A11 | -0.0242525 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0242088 |
| GPHN | gephyrin | -0.0238354 |
| RPL32 | ribosomal protein L32 | -0.0237933 |
| RUSC2 | RUN and SH3 domain containing 2 | -0.0236954 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0234117 |
| TPM2 | tropomyosin 2 (beta) | -0.0233758 |
| BSG | basigin (Ok blood group) | -0.0233517 |
| CDK6 | cyclin-dependent kinase 6 | -0.0233181 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0232979 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0230508 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.0230268 |
| SLMAP | sarcolemma associated protein | -0.0228805 |
| RBM25 | RNA binding motif protein 25 | -0.0226094 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0225814 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | -0.0224818 |
| COTL1 | coactosin-like F-actin binding protein 1 | -0.0223741 |
| DCAF5 | DDB1 and CUL4 associated factor 5 | -0.0223041 |
| RASAL2 | RAS protein activator like 2 | -0.0222067 |
| RPL31 | ribosomal protein L31 | -0.0221512 |
| GNAS | GNAS complex locus | -0.0221027 |
| DNAJC2 | DnaJ (Hsp40) homolog, subfamily C, member 2 | -0.0220832 |
| SYT1 | synaptotagmin I | -0.0219862 |
| B2M | beta-2-microglobulin | -0.0219455 |
| PDE8A | phosphodiesterase 8A | -0.0218503 |
| RAI14 | retinoic acid induced 14 | -0.0217709 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0217471 |
| NXN | nucleoredoxin | -0.0216046 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0214298 |
| FMNL2 | formin-like 2 | -0.021423 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0214042 |
