| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belinostat perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belinostat_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.108937 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.107084 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0929524 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0888954 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0831749 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0797026 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0778355 |
| GOLGA4 | golgin A4 | 0.0674357 |
| TMSB4X | thymosin beta 4, X-linked | 0.0593313 |
| ZNF292 | zinc finger protein 292 | 0.0534211 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0509365 |
| EZR | ezrin | 0.0496681 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0495265 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0484516 |
| NUP58 | nucleoporin 58 | 0.0470718 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0458924 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0447246 |
| AHNAK | AHNAK nucleoprotein | 0.0443573 |
| RTN4 | reticulon 4 | 0.04382 |
| FLNB | filamin B, beta | 0.0432658 |
| ECT2 | epithelial cell transforming 2 | 0.0430665 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0427172 |
| PGK1 | phosphoglycerate kinase 1 | 0.0416132 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0412365 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0409815 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0409256 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0406567 |
| NBAS | neuroblastoma amplified sequence | 0.0404054 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0399053 |
| HDLBP | high density lipoprotein binding protein | 0.0398772 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0388196 |
| QKI | QKI, KH domain containing, RNA binding | 0.0378747 |
| LDHA | lactate dehydrogenase A | 0.0363475 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0356434 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0355525 |
| RBM39 | RNA binding motif protein 39 | 0.0355072 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0352663 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0351826 |
| S100A6 | S100 calcium binding protein A6 | 0.0350986 |
| TMEM41B | transmembrane protein 41B | 0.0350237 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0349602 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0347836 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0345605 |
| NCKAP1 | NCK-associated protein 1 | 0.0342446 |
| TXNIP | thioredoxin interacting protein | 0.0339305 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0335849 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0335643 |
| RNF145 | ring finger protein 145 | 0.0334005 |
| FBXO11 | F-box protein 11 | 0.033122 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0331003 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0326785 |
| CDC73 | cell division cycle 73 | 0.0326671 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0317973 |
| CANX | calnexin | 0.0315617 |
| RLF | rearranged L-myc fusion | 0.0310615 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0308453 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0300836 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0291754 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0289507 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0289159 |
| ANK2 | ankyrin 2, neuronal | 0.0287563 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0287089 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0286765 |
| SLMAP | sarcolemma associated protein | 0.0285545 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0283201 |
| USP3 | ubiquitin specific peptidase 3 | 0.0278552 |
| CALU | calumenin | 0.027701 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0273678 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0271908 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0270154 |
| PTMA | prothymosin, alpha | 0.0268072 |
| SPAG9 | sperm associated antigen 9 | 0.0267034 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0266869 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.026426 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.026411 |
| PARD3 | par-3 family cell polarity regulator | 0.026297 |
| YTHDC1 | YTH domain containing 1 | 0.0262825 |
| OGA | O-GlcNAcase | 0.0261324 |
| PCBP2 | poly(rC) binding protein 2 | 0.0261276 |
| COG5 | component of oligomeric golgi complex 5 | 0.0260905 |
| SMNDC1 | survival motor neuron domain containing 1 | 0.0257428 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0256984 |
| CALR | calreticulin | 0.0255825 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0255507 |
| TXNRD1 | thioredoxin reductase 1 | 0.0252963 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0252243 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0251093 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0250903 |
| TFG | TRK-fused gene | 0.0250631 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0246672 |
| XPO1 | exportin 1 | 0.024488 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0241876 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0240649 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0239921 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0237277 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0236863 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0236836 |
| CD47 | CD47 molecule | 0.0235791 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0235554 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0235042 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0871084 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0740387 |
| RPL35A | ribosomal protein L35a | -0.0704551 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0643228 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0584017 |
| FOXP1 | forkhead box P1 | -0.0527857 |
| BMP10 | bone morphogenetic protein 10 | -0.051344 |
| RPS8 | ribosomal protein S8 | -0.0450557 |
| RPL31 | ribosomal protein L31 | -0.0439439 |
| RPS6 | ribosomal protein S6 | -0.0400506 |
| RPL37A | ribosomal protein L37a | -0.0371215 |
| TMSB10 | thymosin beta 10 | -0.0330996 |
| PKM | pyruvate kinase, muscle | -0.0326706 |
| DIAPH3 | diaphanous-related formin 3 | -0.0310111 |
| RPL9 | ribosomal protein L9 | -0.030505 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0283002 |
| RPS25 | ribosomal protein S25 | -0.0275135 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0273919 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0272448 |
| IGF2 | insulin-like growth factor 2 | -0.0268103 |
| VIM | vimentin | -0.026621 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0263053 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0260483 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0248289 |
| GLI3 | GLI family zinc finger 3 | -0.0239438 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0238945 |
| RPS12 | ribosomal protein S12 | -0.0236646 |
| RPLP1 | ribosomal protein, large, P1 | -0.0234933 |
| MKI67 | marker of proliferation Ki-67 | -0.0228123 |
| RPS19 | ribosomal protein S19 | -0.0226851 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0215416 |
| RPS23 | ribosomal protein S23 | -0.0212769 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.020671 |
| TUBA1B | tubulin, alpha 1b | -0.0206448 |
| NPAS2 | neuronal PAS domain protein 2 | -0.020624 |
| RPS14 | ribosomal protein S14 | -0.0203597 |
| GSE1 | Gse1 coiled-coil protein | -0.0203527 |
| RPLP2 | ribosomal protein, large, P2 | -0.0201144 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0200404 |
| CUX1 | cut-like homeobox 1 | -0.0198985 |
| RPL36A | ribosomal protein L36a | -0.0198554 |
| S100A4 | S100 calcium binding protein A4 | -0.0198553 |
| RPS17 | ribosomal protein S17 | -0.0198095 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.019639 |
| NAV2 | neuron navigator 2 | -0.0195819 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0193543 |
| RPL7A | ribosomal protein L7a | -0.0191302 |
| CRPPA | CDP-L-ribitol pyrophosphorylase A | -0.0188867 |
| RPL34 | ribosomal protein L34 | -0.0182707 |
| EMP3 | epithelial membrane protein 3 | -0.0182127 |
| UNC13A | unc-13 homolog A (C. elegans) | -0.0182104 |
| FTL | ferritin, light polypeptide | -0.0179167 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0178158 |
| RPS13 | ribosomal protein S13 | -0.0175127 |
| RPS24 | ribosomal protein S24 | -0.0171676 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0169321 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0168333 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0161819 |
| POTEF | POTE ankyrin domain family, member F | -0.01546 |
| S100A10 | S100 calcium binding protein A10 | -0.0154484 |
| RPS3 | ribosomal protein S3 | -0.0153555 |
| CENPF | centromere protein F, 350/400kDa | -0.0151812 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0150581 |
| RPL23 | ribosomal protein L23 | -0.0149455 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0148678 |
| RPL37 | ribosomal protein L37 | -0.014827 |
| MACROD2 | MACRO domain containing 2 | -0.0147357 |
| EGFR | epidermal growth factor receptor | -0.0146753 |
| STMN1 | stathmin 1 | -0.0146013 |
| PCNX4 | pecanex 4 | -0.0145576 |
| ITGA10 | integrin, alpha 10 | -0.0144073 |
| CCND1 | cyclin D1 | -0.0138348 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0137087 |
| NDRG1 | N-myc downstream regulated 1 | -0.0135933 |
| FHIT | fragile histidine triad | -0.0135366 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0133597 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0133386 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0131841 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0131417 |
| CEP112 | centrosomal protein 112kDa | -0.0130206 |
| S100A9 | S100 calcium binding protein A9 | -0.0128933 |
| RPL30 | ribosomal protein L30 | -0.0127657 |
| GALNT10 | polypeptide N-acetylgalactosaminyltransferase 10 | -0.0126504 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.0126078 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0125809 |
| AEBP2 | AE binding protein 2 | -0.0125367 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0124988 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0124238 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0124144 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0123737 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0123732 |
| RPS15 | ribosomal protein S15 | -0.0122756 |
| PFN1 | profilin 1 | -0.012254 |
| HMGB1 | high mobility group box 1 | -0.0122159 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0121792 |
| RPL28 | ribosomal protein L28 | -0.0121484 |
| FER1L6 | fer-1-like family member 6 | -0.0121279 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0120732 |
| RPL10A | ribosomal protein L10a | -0.0120178 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0119969 |
