| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belinostat perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Belinostat_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.105055 |
| COL6A3 | collagen, type VI, alpha 3 | 0.104423 |
| STC1 | stanniocalcin 1 | 0.0973281 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0789947 |
| B2M | beta-2-microglobulin | 0.0775108 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0676843 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0675649 |
| HDLBP | high density lipoprotein binding protein | 0.0645681 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0637684 |
| GOLGA4 | golgin A4 | 0.0615494 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0599323 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0587052 |
| FUS | FUS RNA binding protein | 0.0583996 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0583469 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0583002 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0567291 |
| NRXN3 | neurexin 3 | 0.0531267 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0517557 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0504649 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0495517 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0492303 |
| CANX | calnexin | 0.0488564 |
| RARS1 | arginyl-tRNA synthetase 1 | 0.0482153 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0479699 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0476102 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0466631 |
| ANXA2 | annexin A2 | 0.0464796 |
| TOM1L2 | target of myb1-like 2 (chicken) | 0.0448755 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0436056 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0429211 |
| SDC4 | syndecan 4 | 0.0425845 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0416503 |
| CFDP1 | craniofacial development protein 1 | 0.0413516 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0411278 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0402409 |
| FN1 | fibronectin 1 | 0.0397946 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0397396 |
| COG5 | component of oligomeric golgi complex 5 | 0.0395976 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0371641 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0369041 |
| HPCAL1 | hippocalcin-like 1 | 0.0362011 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0360184 |
| RLF | rearranged L-myc fusion | 0.0358294 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0355779 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0354428 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0354302 |
| COG6 | component of oligomeric golgi complex 6 | 0.035312 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0349351 |
| ANLN | anillin, actin binding protein | 0.0346579 |
| STK4 | serine/threonine kinase 4 | 0.034227 |
| SSR1 | signal sequence receptor, alpha | 0.0337823 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0335945 |
| PTMA | prothymosin, alpha | 0.0333884 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0330148 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0327435 |
| MORF4L2 | mortality factor 4 like 2 | 0.0325175 |
| ADM | adrenomedullin | 0.0322948 |
| RTN4 | reticulon 4 | 0.0320903 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0318087 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0318078 |
| CARD16 | caspase recruitment domain family, member 16 | 0.031771 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0317257 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0315626 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0310943 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0309188 |
| LONP2 | lon peptidase 2, peroxisomal | 0.030866 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.03086 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0306126 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0305346 |
| ARRDC3 | arrestin domain containing 3 | 0.0304291 |
| HLA-C | major histocompatibility complex, class I, C | 0.0301934 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0299048 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.02979 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0297097 |
| ACTN4 | actinin, alpha 4 | 0.029553 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0294062 |
| ARF4 | ADP-ribosylation factor 4 | 0.029337 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0287576 |
| PMM2 | phosphomannomutase 2 | 0.0287009 |
| GPR107 | G protein-coupled receptor 107 | 0.0284571 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0283327 |
| NOTCH2 | notch 2 | 0.0283241 |
| PRSS23 | protease, serine, 23 | 0.0283043 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0278347 |
| CLIC4 | chloride intracellular channel 4 | 0.0275665 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0274467 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0273958 |
| CTSB | cathepsin B | 0.027327 |
| FOXO3 | forkhead box O3 | 0.0271831 |
| HBS1L | HBS1-like translational GTPase | 0.0271443 |
| YME1L1 | YME1-like 1 ATPase | 0.0271157 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0270487 |
| SEC13 | SEC13 homolog (S. cerevisiae) | 0.0268863 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0268369 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0268182 |
| USP53 | ubiquitin specific peptidase 53 | 0.0266628 |
| WTAP | Wilms tumor 1 associated protein | 0.0266052 |
| C1R | complement component 1, r subcomponent | 0.0265487 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0264558 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0264332 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.195866 |
| VIM | vimentin | -0.0832735 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0801069 |
| LMNA | lamin A/C | -0.0681563 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0635547 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.060697 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0481785 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0438831 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.043653 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0434888 |
| TMSB10 | thymosin beta 10 | -0.0430881 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0403858 |
| NAV1 | neuron navigator 1 | -0.0398669 |
| RPL28 | ribosomal protein L28 | -0.0391649 |
| ENO1 | enolase 1, (alpha) | -0.0375818 |
| PKM | pyruvate kinase, muscle | -0.037484 |
| RHEB | Ras homolog enriched in brain | -0.0374825 |
| BSG | basigin (Ok blood group) | -0.0360839 |
| COL1A1 | collagen, type I, alpha 1 | -0.0345736 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0339324 |
| POTEF | POTE ankyrin domain family, member F | -0.0336124 |
| RPL37A | ribosomal protein L37a | -0.0333888 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0330144 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.0328208 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.032095 |
| CALD1 | caldesmon 1 | -0.0319637 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0319473 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0317765 |
| PURB | purine-rich element binding protein B | -0.0317329 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0309349 |
| RPL32 | ribosomal protein L32 | -0.0309054 |
| USP47 | ubiquitin specific peptidase 47 | -0.0308778 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0307611 |
| DSTN | destrin (actin depolymerizing factor) | -0.0306964 |
| FBXO11 | F-box protein 11 | -0.0304265 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.029273 |
| AAK1 | AP2 associated kinase 1 | -0.0287608 |
| H3-3B | H3.3 histone B | -0.0286018 |
| SPAG9 | sperm associated antigen 9 | -0.0285182 |
| SMAD3 | SMAD family member 3 | -0.0282051 |
| WNT5A | wingless-type MMTV integration site family, member 5A | -0.0279976 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0279834 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0278448 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.027586 |
| EFNA5 | ephrin-A5 | -0.027556 |
| PDS5B | PDS5 cohesin associated factor B | -0.0273699 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0272408 |
| RPL36A | ribosomal protein L36a | -0.0269214 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0268174 |
| ETV6 | ets variant 6 | -0.0267745 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0262186 |
| RPL23 | ribosomal protein L23 | -0.0260733 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0255549 |
| NDRG1 | N-myc downstream regulated 1 | -0.0254967 |
| KIAA0319L | KIAA0319-like | -0.025496 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0254394 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0253543 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0251699 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.024855 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0248396 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0248339 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0248138 |
| TRIM9 | tripartite motif containing 9 | -0.0248042 |
| ATXN2 | ataxin 2 | -0.0248034 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0246786 |
| UBTD2 | ubiquitin domain containing 2 | -0.0246427 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0245572 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0245051 |
| RPS10 | ribosomal protein S10 | -0.0244043 |
| NHSL1 | NHS-like 1 | -0.0242467 |
| ARF6 | ADP-ribosylation factor 6 | -0.0240042 |
| LOX | lysyl oxidase | -0.0239132 |
| RAB10 | RAB10, member RAS oncogene family | -0.0238761 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0238498 |
| CERT1 | ceramide transporter 1 | -0.0238498 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0237033 |
| CACNA1C | calcium channel, voltage-dependent, L type, alpha 1C subunit | -0.0236919 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.023557 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.023491 |
| MAP4 | microtubule-associated protein 4 | -0.0234416 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0234302 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | -0.0234142 |
| PDZD2 | PDZ domain containing 2 | -0.0234131 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.023358 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0232566 |
| ARHGAP17 | Rho GTPase activating protein 17 | -0.0230796 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0230184 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0229254 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0228762 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0228382 |
| SQSTM1 | sequestosome 1 | -0.0227783 |
| EGFR | epidermal growth factor receptor | -0.0227752 |
| FTL | ferritin, light polypeptide | -0.0227102 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 | -0.0225534 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0224821 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0224051 |
| TPI1 | triosephosphate isomerase 1 | -0.0222642 |
| MORC3 | MORC family CW-type zinc finger 3 | -0.0222253 |
| RAI1 | retinoic acid induced 1 | -0.02214 |
| MXI1 | MAX interactor 1, dimerization protein | -0.021854 |