| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil (mesylate) perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Belumosudil (mesylate)_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CADM2 | cell adhesion molecule 2 | 0.0394105 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0376516 |
| MYOF | myoferlin | 0.0370926 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0366457 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0314021 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0281027 |
| EGR1 | early growth response 1 | 0.0254857 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0240866 |
| INTS6 | integrator complex subunit 6 | 0.0230441 |
| RPL4 | ribosomal protein L4 | 0.0225248 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0206406 |
| ASPH | aspartate beta-hydroxylase | 0.0200989 |
| HMGA2 | high mobility group AT-hook 2 | 0.0195861 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0194779 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0192404 |
| RAD51B | RAD51 paralog B | 0.0189347 |
| PRELID2 | PRELI domain containing 2 | 0.0182036 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0178421 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0167796 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0164067 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0163487 |
| GPC6 | glypican 6 | 0.0162648 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0161765 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0159384 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0153834 |
| PDE10A | phosphodiesterase 10A | 0.0150897 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.014915 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0148571 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0147315 |
| FN1 | fibronectin 1 | 0.0147243 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0146741 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0145407 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.014147 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0139816 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0139664 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | 0.0139252 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0139019 |
| PCDH7 | protocadherin 7 | 0.013561 |
| NSD3 | nuclear receptor binding SET domain protein 3 | 0.013537 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0134096 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0133315 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0133105 |
| H1-0 | H1.0 linker histone | 0.0132811 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0132376 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0131436 |
| CHKA | choline kinase alpha | 0.0131182 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0130084 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0129593 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0126966 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0126827 |
| EFNA5 | ephrin-A5 | 0.0126599 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0124269 |
| OPHN1 | oligophrenin 1 | 0.0123918 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0122395 |
| FAM193A | family with sequence similarity 193, member A | 0.0121488 |
| FHIT | fragile histidine triad | 0.0120157 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0119772 |
| LRRC23 | leucine rich repeat containing 23 | 0.0119471 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0118788 |
| ADIPOR2 | adiponectin receptor 2 | 0.0118601 |
| LMO7 | LIM domain 7 | 0.0118479 |
| NBEAL1 | neurobeachin-like 1 | 0.0118409 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0118102 |
| DST | dystonin | 0.0117216 |
| ACBD6 | acyl-CoA binding domain containing 6 | 0.0116584 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0116044 |
| ZNF532 | zinc finger protein 532 | 0.0115826 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 0.0114902 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0112854 |
| SKI | SKI proto-oncogene | 0.0110584 |
| DENND1A | DENN/MADD domain containing 1A | 0.0110387 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 0.0108931 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0107867 |
| DSPP | dentin sialophosphoprotein | 0.0107817 |
| GLIS3 | GLIS family zinc finger 3 | 0.0107617 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0107417 |
| SGMS2 | sphingomyelin synthase 2 | 0.0106924 |
| EHBP1 | EH domain binding protein 1 | 0.0106723 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0105512 |
| RUNX1 | runt-related transcription factor 1 | 0.0104377 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0103178 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0102981 |
| SNX14 | sorting nexin 14 | 0.0102676 |
| AASS | aminoadipate-semialdehyde synthase | 0.0102134 |
| IGF2 | insulin-like growth factor 2 | 0.0101871 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0101013 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | 0.0100728 |
| MSH4 | mutS homolog 4 | 0.0100118 |
| PSEN1 | presenilin 1 | 0.00992228 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.00990162 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.00988136 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.00983743 |
| CCND1 | cyclin D1 | 0.0098077 |
| MTAP | methylthioadenosine phosphorylase | 0.00969639 |
| RBBP6 | retinoblastoma binding protein 6 | 0.00969259 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.00968713 |
| IFRD1 | interferon-related developmental regulator 1 | 0.00968434 |
| SAV1 | salvador family WW domain containing protein 1 | 0.00963953 |
| PILRA | paired immunoglobin-like type 2 receptor alpha | 0.0096373 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.00963381 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MEST | mesoderm specific transcript | -0.189246 |
| VIM | vimentin | -0.119454 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0868326 |
| PTMA | prothymosin, alpha | -0.0732026 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0728477 |
| PEG10 | paternally expressed 10 | -0.0664858 |
| PCBP2 | poly(rC) binding protein 2 | -0.0555503 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0545536 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0523366 |
| MED13L | mediator complex subunit 13-like | -0.0519487 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0505068 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0504375 |
| CENPF | centromere protein F, 350/400kDa | -0.0475862 |
| NFIB | nuclear factor I/B | -0.0456515 |
| COL1A2 | collagen, type I, alpha 2 | -0.0445899 |
| PHIP | pleckstrin homology domain interacting protein | -0.0428455 |
| SRPK2 | SRSF protein kinase 2 | -0.0412871 |
| CANX | calnexin | -0.0398476 |
| ZNF292 | zinc finger protein 292 | -0.0396258 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.0382222 |
| HMGB2 | high mobility group box 2 | -0.0378109 |
| ENAH | enabled homolog (Drosophila) | -0.0375288 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0369788 |
| PCM1 | pericentriolar material 1 | -0.0361788 |
| LDHA | lactate dehydrogenase A | -0.0352225 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0351713 |
| QKI | QKI, KH domain containing, RNA binding | -0.0347331 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0347099 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0344624 |
| SEPTIN11 | septin 11 | -0.0339556 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0332832 |
| MATR3 | matrin 3 | -0.0320331 |
| NFIA | nuclear factor I/A | -0.0320064 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0315926 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0315315 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0309113 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0308268 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0307886 |
| BCOR | BCL6 corepressor | -0.0304597 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0303523 |
| CALR | calreticulin | -0.0300178 |
| MEOX2 | mesenchyme homeobox 2 | -0.0297405 |
| RBM25 | RNA binding motif protein 25 | -0.0293784 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0292145 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0291834 |
| RAD21 | RAD21 homolog (S. pombe) | -0.029115 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0291123 |
| RPS27A | ribosomal protein S27a | -0.0286954 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0285058 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0281163 |
| SFTPA2 | surfactant protein A2 | -0.0270929 |
| UBC | ubiquitin C | -0.0269509 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.026901 |
| RPS3 | ribosomal protein S3 | -0.0268938 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0261054 |
| TMSB10 | thymosin beta 10 | -0.0259419 |
| RPLP1 | ribosomal protein, large, P1 | -0.0259115 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0257514 |
| GOLGA4 | golgin A4 | -0.0256175 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0255227 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0252839 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0252078 |
| CENPE | centromere protein E, 312kDa | -0.0250712 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | -0.0250612 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0245974 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0241223 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.023916 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0239154 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0237807 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.023547 |
| RPS6 | ribosomal protein S6 | -0.0234389 |
| MKI67 | marker of proliferation Ki-67 | -0.0233273 |
| TUBB | tubulin, beta class I | -0.0231938 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0230149 |
| RPL23 | ribosomal protein L23 | -0.0228968 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0227114 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0225799 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0224452 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0223629 |
| POU2F1 | POU class 2 homeobox 1 | -0.0223477 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0221524 |
| TMSB4X | thymosin beta 4, X-linked | -0.0219901 |
| RACK1 | receptor for activated C kinase 1 | -0.0219481 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | -0.0217841 |
| YBX1 | Y box binding protein 1 | -0.0216258 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | -0.0215355 |
| ITGAV | integrin, alpha V | -0.0214934 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.021483 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0214444 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0212726 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0211181 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0210888 |
| ZNF148 | zinc finger protein 148 | -0.021017 |
| PGK1 | phosphoglycerate kinase 1 | -0.0209593 |
| CBX3 | chromobox homolog 3 | -0.0208416 |
| SCARB2 | scavenger receptor class B, member 2 | -0.0206989 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0206867 |
| TNPO1 | transportin 1 | -0.0203858 |
| KIF11 | kinesin family member 11 | -0.0202907 |
| RPL26 | ribosomal protein L26 | -0.0202358 |
