| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil (mesylate) perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belumosudil (mesylate)_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.140424 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.110526 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.101793 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0933177 |
| UBC | ubiquitin C | 0.089886 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0893997 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0883521 |
| TXNRD1 | thioredoxin reductase 1 | 0.0768407 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0763676 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0750311 |
| EZR | ezrin | 0.0698485 |
| SGMS2 | sphingomyelin synthase 2 | 0.0687603 |
| TRRAP | transformation/transcription domain-associated protein | 0.064108 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0621884 |
| RIOK3 | RIO kinase 3 | 0.0593577 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0561348 |
| EMP1 | epithelial membrane protein 1 | 0.0553995 |
| SIK3 | SIK family kinase 3 | 0.0534609 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0514682 |
| CRY1 | cryptochrome circadian clock 1 | 0.0511437 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.049608 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0495987 |
| GOLGB1 | golgin B1 | 0.0494036 |
| TPM3 | tropomyosin 3 | 0.0489973 |
| PMM2 | phosphomannomutase 2 | 0.0484883 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0480885 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0475427 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0471613 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0471085 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0466178 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0451002 |
| NOP58 | NOP58 ribonucleoprotein | 0.0450321 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0448003 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0445359 |
| RPS2 | ribosomal protein S2 | 0.0443175 |
| FBXO11 | F-box protein 11 | 0.0436951 |
| MYO1E | myosin IE | 0.0427301 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0421713 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0421339 |
| UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.042129 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0413166 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0412795 |
| SMAD3 | SMAD family member 3 | 0.0402036 |
| OXSR1 | oxidative stress responsive 1 | 0.0396492 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0394846 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0391122 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0391112 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0385739 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0383726 |
| JMJD1C | jumonji domain containing 1C | 0.0378606 |
| SPAG9 | sperm associated antigen 9 | 0.037561 |
| ACTN4 | actinin, alpha 4 | 0.0367492 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0366862 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0361433 |
| TJP1 | tight junction protein 1 | 0.0356494 |
| CALU | calumenin | 0.0350652 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0345139 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0344631 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0341511 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.033988 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0337135 |
| SUCO | SUN domain containing ossification factor | 0.0336547 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0334979 |
| TAOK3 | TAO kinase 3 | 0.0334201 |
| SVIL | supervillin | 0.0328662 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0327336 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | 0.0322335 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0319058 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0318909 |
| NUP98 | nucleoporin 98kDa | 0.0317237 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0317117 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0314976 |
| GDA | guanine deaminase | 0.0314877 |
| SQSTM1 | sequestosome 1 | 0.0306471 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0303477 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0302197 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0301674 |
| RASAL2 | RAS protein activator like 2 | 0.0300032 |
| RPL4 | ribosomal protein L4 | 0.029902 |
| EFNA5 | ephrin-A5 | 0.0296536 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0289687 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0288795 |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) | 0.0288191 |
| RUNX1 | runt-related transcription factor 1 | 0.0285126 |
| MCL1 | myeloid cell leukemia 1 | 0.0284748 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0284023 |
| VMP1 | vacuole membrane protein 1 | 0.028373 |
| SEPTIN7 | septin 7 | 0.0281963 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | 0.0281708 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0281618 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0281119 |
| JAK1 | Janus kinase 1 | 0.0280255 |
| WWC1 | WW and C2 domain containing 1 | 0.0278207 |
| LOC112694756 | uncharaterized LOC112694756 | 0.027763 |
| FUS | FUS RNA binding protein | 0.0277404 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0277329 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0277305 |
| MTDH | metadherin | 0.027414 |
| CDK13 | cyclin-dependent kinase 13 | 0.0272582 |
| RLF | rearranged L-myc fusion | 0.0270802 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | -0.111478 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0934948 |
| LAMB3 | laminin, beta 3 | -0.0822973 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.07995 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.077961 |
| NDRG1 | N-myc downstream regulated 1 | -0.0753951 |
| ITGA6 | integrin, alpha 6 | -0.0713812 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0692501 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0672698 |
| FERMT1 | fermitin family member 1 | -0.0661807 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0653105 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0651438 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0630944 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0613293 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0595761 |
| VCAN | versican | -0.0534569 |
| FAM13A | family with sequence similarity 13, member A | -0.0525983 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0516103 |
| VCL | vinculin | -0.0495544 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | -0.048532 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0483796 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0479244 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0477409 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0472654 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0453132 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0449596 |
| UPP1 | uridine phosphorylase 1 | -0.0429425 |
| CD2AP | CD2-associated protein | -0.0417145 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.041705 |
| ASPH | aspartate beta-hydroxylase | -0.0416285 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0415329 |
| MXD1 | MAX dimerization protein 1 | -0.0412882 |
| PRSS3 | protease, serine, 3 | -0.0409496 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0402451 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0398012 |
| ZNF292 | zinc finger protein 292 | -0.0397674 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0397631 |
| TMSB10 | thymosin beta 10 | -0.0397377 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0392056 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0389736 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0387944 |
| FAM3C | family with sequence similarity 3, member C | -0.0381026 |
| PERP | PERP, TP53 apoptosis effector | -0.0367956 |
| TPM4 | tropomyosin 4 | -0.0367758 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0365507 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 | -0.0360281 |
| RPL35A | ribosomal protein L35a | -0.0358145 |
| OGA | O-GlcNAcase | -0.0358141 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0350866 |
| SLMAP | sarcolemma associated protein | -0.0350745 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0338546 |
| SLC35F3 | solute carrier family 35, member F3 | -0.03339 |
| CLMP | CXADR-like membrane protein | -0.0333139 |
| S100A10 | S100 calcium binding protein A10 | -0.0331687 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0322144 |
| FAM107B | family with sequence similarity 107, member B | -0.0320555 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0315364 |
| SBF2 | SET binding factor 2 | -0.0315154 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0310323 |
| EXOC1 | exocyst complex component 1 | -0.0305427 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0303968 |
| ANLN | anillin, actin binding protein | -0.0302874 |
| S100A11 | S100 calcium binding protein A11 | -0.0300096 |
| PTMA | prothymosin, alpha | -0.029821 |
| RPS12 | ribosomal protein S12 | -0.0296498 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0294886 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0294281 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0273971 |
| HMGA1 | high mobility group AT-hook 1 | -0.0271392 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0271214 |
| DSG3 | desmoglein 3 | -0.0270385 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0261669 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0261018 |
| DIAPH2 | diaphanous-related formin 2 | -0.0258015 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.025708 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0256333 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0256193 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0255914 |
| RPL31 | ribosomal protein L31 | -0.0255428 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0250555 |
| RNF213 | ring finger protein 213 | -0.0250082 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | -0.0247852 |
| BMERB1 | bMERB domain containing 1 | -0.0245782 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0245044 |
| LAMC2 | laminin, gamma 2 | -0.0244155 |
| MT2A | metallothionein 2A | -0.0243531 |
| AFDN | afadin, adherens junction formation factor | -0.0242512 |
| JUP | junction plakoglobin | -0.024154 |
| TGFA | transforming growth factor, alpha | -0.0241357 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | -0.0240101 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0238193 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0236045 |
| CTBP2 | C-terminal binding protein 2 | -0.0235389 |
| RPL23 | ribosomal protein L23 | -0.0233862 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0231812 |
| STK39 | serine threonine kinase 39 | -0.0231408 |
| ZNF395 | zinc finger protein 395 | -0.023043 |
| PLEK2 | pleckstrin 2 | -0.0227272 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0227231 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0226376 |
