| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil (mesylate) perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Belumosudil (mesylate)_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS6 | integrator complex subunit 6 | 0.049405 |
| UBC | ubiquitin C | 0.0363731 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0338266 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0317993 |
| VCP | valosin containing protein | 0.0289874 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0286226 |
| STXBP4 | syntaxin binding protein 4 | 0.0272999 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0240296 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0231456 |
| PLSCR2 | phospholipid scramblase 2 | 0.0202693 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0184029 |
| SCFD1 | sec1 family domain containing 1 | 0.0180131 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0179327 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0176196 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0175951 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0174547 |
| TPM3 | tropomyosin 3 | 0.0163413 |
| FAM219A | family with sequence similarity 219, member A | 0.0162999 |
| GOLGB1 | golgin B1 | 0.0159238 |
| ATXN1 | ataxin 1 | 0.0153433 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0153414 |
| SET | SET nuclear proto-oncogene | 0.0152624 |
| SQSTM1 | sequestosome 1 | 0.0152147 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0151589 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0151238 |
| UNC13B | unc-13 homolog B (C. elegans) | 0.0150955 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0146057 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0145764 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0144518 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0143115 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0140494 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0139712 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0138467 |
| PNN | pinin, desmosome associated protein | 0.0138368 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.013759 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0137104 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0133095 |
| ZNF638 | zinc finger protein 638 | 0.0132662 |
| TENM2 | teneurin transmembrane protein 2 | 0.0129594 |
| MAP7 | microtubule-associated protein 7 | 0.0127593 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0127421 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0127348 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 | 0.012532 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0123473 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0121152 |
| CLEC2D | C-type lectin domain family 2, member D | 0.0120463 |
| DUSP16 | dual specificity phosphatase 16 | 0.0119663 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0118579 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0118534 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0117748 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0117496 |
| PGM3 | phosphoglucomutase 3 | 0.0117403 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0116807 |
| MYO10 | myosin X | 0.0112972 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0112887 |
| KRT86 | keratin 86, type II | 0.0111959 |
| TTC17 | tetratricopeptide repeat domain 17 | 0.0111081 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0110376 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0110067 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0107586 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0107273 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0106053 |
| CENPF | centromere protein F, 350/400kDa | 0.0105764 |
| MBD4 | methyl-CpG binding domain protein 4 | 0.0105763 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0104577 |
| HOMER1 | homer scaffolding protein 1 | 0.0104095 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0104065 |
| DCAF6 | DDB1 and CUL4 associated factor 6 | 0.0103481 |
| CLIC4 | chloride intracellular channel 4 | 0.010222 |
| SNX14 | sorting nexin 14 | 0.0100617 |
| ATF6 | activating transcription factor 6 | 0.0100546 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0100355 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.00995231 |
| MED13 | mediator complex subunit 13 | 0.00990636 |
| LARP1B | La ribonucleoprotein domain family, member 1B | 0.0098535 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.00975649 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00973248 |
| AGO3 | argonaute RISC catalytic component 3 | 0.00969322 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.00963303 |
| JAK1 | Janus kinase 1 | 0.00959979 |
| UMAD1 | UBAP1-MVB12-associated (UMA) domain containing 1 | 0.00949806 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0094064 |
| UBAP2 | ubiquitin associated protein 2 | 0.00928571 |
| ZNF292 | zinc finger protein 292 | 0.00927598 |
| KIF16B | kinesin family member 16B | 0.00925989 |
| RTN3 | reticulon 3 | 0.00924786 |
| LEMD3 | LEM domain containing 3 | 0.0091791 |
| AGO2 | argonaute RISC catalytic component 2 | 0.00915335 |
| SNX13 | sorting nexin 13 | 0.00914952 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.00909789 |
| FRYL | FRY-like | 0.00908617 |
| HEATR5A | HEAT repeat containing 5A | 0.00907771 |
| RLF | rearranged L-myc fusion | 0.00907316 |
| NDUFAF6 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 | 0.00905195 |
| USO1 | USO1 vesicle transport factor | 0.00902364 |
| MBOAT1 | membrane bound O-acyltransferase domain containing 1 | 0.00901002 |
| NCOR2 | nuclear receptor corepressor 2 | 0.00891428 |
| PCM1 | pericentriolar material 1 | 0.00883599 |
| GPATCH2L | G patch domain containing 2-like | 0.00880599 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.00874673 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | -0.280809 |
| RPL19 | ribosomal protein L19 | -0.212442 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.122014 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0991914 |
| RPL35A | ribosomal protein L35a | -0.0928228 |
| TMSB10 | thymosin beta 10 | -0.0904232 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0859509 |
| PTMA | prothymosin, alpha | -0.0744491 |
| LASP1 | LIM and SH3 protein 1 | -0.0668382 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0625974 |
| CCND1 | cyclin D1 | -0.0600384 |
| TMSB4X | thymosin beta 4, X-linked | -0.0594794 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0567704 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0544561 |
| ACTG1 | actin gamma 1 | -0.0538495 |
| ASPH | aspartate beta-hydroxylase | -0.0532469 |
| RPL12 | ribosomal protein L12 | -0.0508132 |
| CDK12 | cyclin-dependent kinase 12 | -0.0451735 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0449781 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0446416 |
| CLTC | clathrin, heavy chain (Hc) | -0.0445035 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0426944 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0402837 |
| RPS24 | ribosomal protein S24 | -0.0400378 |
| S100A9 | S100 calcium binding protein A9 | -0.0394737 |
| OSMR | oncostatin M receptor | -0.0393668 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0375204 |
| RPL34 | ribosomal protein L34 | -0.0364367 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0362937 |
| PGK1 | phosphoglycerate kinase 1 | -0.0358284 |
| HLA-C | major histocompatibility complex, class I, C | -0.0355675 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0347282 |
| B2M | beta-2-microglobulin | -0.0347205 |
| MT2A | metallothionein 2A | -0.0340601 |
| KRT8 | keratin 8, type II | -0.0337812 |
| RPS19 | ribosomal protein S19 | -0.0332861 |
| PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | -0.0327496 |
| GNAS | GNAS complex locus | -0.0313137 |
| HLA-B | major histocompatibility complex, class I, B | -0.0313102 |
| KRT19 | keratin 19, type I | -0.0307039 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0305397 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0300186 |
| LOC112694756 | uncharaterized LOC112694756 | -0.029972 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0294006 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0293363 |
| RPL9 | ribosomal protein L9 | -0.029207 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.028914 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0286073 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0284347 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0283866 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0281784 |
| CDH15 | cadherin 15, type 1, M-cadherin (myotubule) | -0.0281188 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0271061 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0268678 |
| RPLP1 | ribosomal protein, large, P1 | -0.0266963 |
| TMEM123 | transmembrane protein 123 | -0.0266391 |
| S100A6 | S100 calcium binding protein A6 | -0.0262712 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0260604 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | -0.0260503 |
| RPL26 | ribosomal protein L26 | -0.0259844 |
| CBX3 | chromobox homolog 3 | -0.025939 |
| LMNA | lamin A/C | -0.0259145 |
| KRT18 | keratin 18, type I | -0.0254075 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0248029 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | -0.024425 |
| RPL27A | ribosomal protein L27a | -0.0240763 |
| ANXA2 | annexin A2 | -0.0240093 |
| KRT7 | keratin 7, type II | -0.0238366 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0234355 |
| RPL35 | ribosomal protein L35 | -0.0234071 |
| S100A8 | S100 calcium binding protein A8 | -0.0231011 |
| RPL11 | ribosomal protein L11 | -0.0230951 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0228576 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0227002 |
| S100A14 | S100 calcium binding protein A14 | -0.0224334 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0223935 |
| RPL30 | ribosomal protein L30 | -0.0219445 |
| RPL31 | ribosomal protein L31 | -0.0217779 |
| RRBP1 | ribosome binding protein 1 | -0.0217484 |
| PLSCR1 | phospholipid scramblase 1 | -0.0215664 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0215447 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0212723 |
| FTL | ferritin, light polypeptide | -0.021232 |
| RPS21 | ribosomal protein S21 | -0.0210427 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0210167 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0209835 |
| PFDN4 | prefoldin subunit 4 | -0.0209302 |
| RPL32 | ribosomal protein L32 | -0.020809 |
| RPL37 | ribosomal protein L37 | -0.020796 |
| TUBB | tubulin, beta class I | -0.0207553 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0205177 |
| TXNRD1 | thioredoxin reductase 1 | -0.0205103 |
| RPL8 | ribosomal protein L8 | -0.0203532 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0202017 |
| CD63 | CD63 molecule | -0.0201845 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0200823 |
| RPLP0 | ribosomal protein, large, P0 | -0.0200022 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0194562 |
| MIEN1 | migration and invasion enhancer 1 | -0.0191934 |
| TPI1 | triosephosphate isomerase 1 | -0.0191163 |
