| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil (mesylate) perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belumosudil (mesylate)_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0380058 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0362085 |
| CDC73 | cell division cycle 73 | 0.0351398 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0339124 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0292651 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0278421 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0273188 |
| TMEM178B | transmembrane protein 178B | 0.0259332 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0251011 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0220095 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0214866 |
| UBC | ubiquitin C | 0.0201149 |
| COG5 | component of oligomeric golgi complex 5 | 0.0181029 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0163955 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0158504 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0157102 |
| COPA | coatomer protein complex, subunit alpha | 0.0153603 |
| RPL4 | ribosomal protein L4 | 0.014748 |
| MRTFA | myocardin related transcription factor A | 0.0146768 |
| RBM33 | RNA binding motif protein 33 | 0.01464 |
| CD109 | CD109 molecule | 0.0143418 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0139598 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0135799 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0135692 |
| RNF145 | ring finger protein 145 | 0.0133438 |
| EXOC4 | exocyst complex component 4 | 0.0133192 |
| INPP5F | inositol polyphosphate-5-phosphatase F | 0.0131228 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.012999 |
| ANO6 | anoctamin 6 | 0.0128637 |
| ARRDC3 | arrestin domain containing 3 | 0.0127461 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0123832 |
| RO60 | Ro60, Y RNA binding protein | 0.0118531 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0118 |
| NAV2 | neuron navigator 2 | 0.0117837 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0116639 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0113947 |
| IFRD1 | interferon-related developmental regulator 1 | 0.011393 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0113849 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.011261 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0111654 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0109985 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0108912 |
| NEK7 | NIMA-related kinase 7 | 0.0108416 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0107203 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0106854 |
| NAV1 | neuron navigator 1 | 0.0106732 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0106629 |
| SETBP1 | SET binding protein 1 | 0.0106221 |
| CCNL1 | cyclin L1 | 0.0105128 |
| SAMTOR | S-adenosylmethionine sensor upstream of mTORC1 | 0.0104916 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | 0.0101803 |
| SRPK2 | SRSF protein kinase 2 | 0.0100075 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.00997485 |
| FBXO7 | F-box protein 7 | 0.00979469 |
| NHSL1 | NHS-like 1 | 0.00974681 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.00972983 |
| STOM | stomatin | 0.00970012 |
| TPM3 | tropomyosin 3 | 0.009688 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.00961167 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.00955789 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.00954327 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.00935682 |
| AFDN | afadin, adherens junction formation factor | 0.00933715 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | 0.00932775 |
| DST | dystonin | 0.00932638 |
| GOLGA4 | golgin A4 | 0.00917146 |
| SPAG9 | sperm associated antigen 9 | 0.00909468 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.00900308 |
| ZNF277 | zinc finger protein 277 | 0.00895918 |
| SEC24A | SEC24 family member A | 0.00889142 |
| TMF1 | TATA element modulatory factor 1 | 0.00885918 |
| VMP1 | vacuole membrane protein 1 | 0.00880357 |
| SUCO | SUN domain containing ossification factor | 0.00855163 |
| TOP1 | topoisomerase (DNA) I | 0.00854833 |
| HELZ | helicase with zinc finger | 0.00851973 |
| ZFP36 | ZFP36 ring finger protein | 0.00842466 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.00840444 |
| DSCAM | Down syndrome cell adhesion molecule | 0.00834864 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.00834223 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.00830772 |
| BRD2 | bromodomain containing 2 | 0.0082306 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00822787 |
| TNPO3 | transportin 3 | 0.00822011 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.00821133 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.00819236 |
| TRRAP | transformation/transcription domain-associated protein | 0.00818504 |
| NOTCH2 | notch 2 | 0.00817784 |
| MTERF1 | mitochondrial transcription termination factor 1 | 0.00808393 |
| EMP1 | epithelial membrane protein 1 | 0.00802474 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.00798336 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.00793646 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0078969 |
| TBCD | tubulin folding cofactor D | 0.00788966 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.00782644 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.00777466 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.00768367 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.00767966 |
| MSN | moesin | 0.0076533 |
| RPL3 | ribosomal protein L3 | 0.00763058 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.00755257 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VGF | VGF nerve growth factor inducible | -0.163394 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.161821 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.132459 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.125513 |
| VIM | vimentin | -0.120503 |
| NLGN1 | neuroligin 1 | -0.111123 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.110222 |
| FN1 | fibronectin 1 | -0.106215 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.102891 |
| TMSB10 | thymosin beta 10 | -0.101265 |
| GPC6 | glypican 6 | -0.0908448 |
| HLA-B | major histocompatibility complex, class I, B | -0.0867741 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0686281 |
| S100A6 | S100 calcium binding protein A6 | -0.0598451 |
| PTMA | prothymosin, alpha | -0.0590716 |
| ACTG1 | actin gamma 1 | -0.0507976 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0506612 |
| DCT | dopachrome tautomerase | -0.0472275 |
| MACROD2 | MACRO domain containing 2 | -0.0461969 |
| ASPH | aspartate beta-hydroxylase | -0.0439495 |
| RPL35A | ribosomal protein L35a | -0.0422967 |
| FRMD4A | FERM domain containing 4A | -0.0422425 |
| GDF15 | growth differentiation factor 15 | -0.0414701 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0406905 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0406117 |
| PGK1 | phosphoglycerate kinase 1 | -0.0403209 |
| SCFD2 | sec1 family domain containing 2 | -0.0397888 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0376942 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0353857 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0342959 |
| NAV3 | neuron navigator 3 | -0.0339796 |
| OXR1 | oxidation resistance 1 | -0.0330891 |
| FTL | ferritin, light polypeptide | -0.0329423 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0325716 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0325031 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0319776 |
| FMN1 | formin 1 | -0.0316864 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0311676 |
| TRIM2 | tripartite motif containing 2 | -0.0311266 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0304937 |
| RPLP1 | ribosomal protein, large, P1 | -0.0301084 |
| CDK14 | cyclin-dependent kinase 14 | -0.0299282 |
| CD63 | CD63 molecule | -0.0298564 |
| CALD1 | caldesmon 1 | -0.0295351 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0275679 |
| GNAS | GNAS complex locus | -0.0274693 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0267777 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0267672 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0266758 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0266675 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0264573 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0263278 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0260652 |
| RPL34 | ribosomal protein L34 | -0.0259333 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0258152 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0257292 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | -0.0255393 |
| EHBP1 | EH domain binding protein 1 | -0.0253525 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0253384 |
| B2M | beta-2-microglobulin | -0.0253374 |
| RPS19 | ribosomal protein S19 | -0.0251851 |
| PTCHD4 | patched domain containing 4 | -0.024903 |
| TPI1 | triosephosphate isomerase 1 | -0.0248192 |
| IER3 | immediate early response 3 | -0.024747 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0247433 |
| CTSD | cathepsin D | -0.024622 |
| COL19A1 | collagen, type XIX, alpha 1 | -0.0245647 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0243719 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0243237 |
| NDRG1 | N-myc downstream regulated 1 | -0.0240207 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0237797 |
| GHR | growth hormone receptor | -0.0234267 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0231953 |
| POTEF | POTE ankyrin domain family, member F | -0.0227024 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0226673 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0225757 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0225196 |
| ENO1 | enolase 1, (alpha) | -0.0222921 |
| IGF2 | insulin-like growth factor 2 | -0.0222326 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0220092 |
| HLA-A | major histocompatibility complex, class I, A | -0.0217472 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0217434 |
| S100A9 | S100 calcium binding protein A9 | -0.021741 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0217021 |
| PDE10A | phosphodiesterase 10A | -0.0216363 |
| RUNX1 | runt-related transcription factor 1 | -0.0211323 |
| SFTPA2 | surfactant protein A2 | -0.0210425 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0210108 |
| RPS24 | ribosomal protein S24 | -0.0207442 |
| TNNC1 | troponin C type 1 (slow) | -0.0206816 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0203346 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0203147 |
| CALR | calreticulin | -0.0201773 |
| LMNA | lamin A/C | -0.0201723 |
| ZNF704 | zinc finger protein 704 | -0.0201646 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0198857 |
| TAGLN2 | transgelin 2 | -0.0193861 |
| RPL31 | ribosomal protein L31 | -0.0192252 |
| MTDH | metadherin | -0.0191365 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0191126 |
