| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil (mesylate) perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belumosudil (mesylate)_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CP | ceruloplasmin (ferroxidase) | 0.139472 |
| APOL1 | apolipoprotein L, 1 | 0.136939 |
| MMP7 | matrix metallopeptidase 7 | 0.126403 |
| FNDC3B | fibronectin type III domain containing 3B | 0.118199 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0993792 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0868986 |
| EFNA5 | ephrin-A5 | 0.0741452 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0736521 |
| B2M | beta-2-microglobulin | 0.0714135 |
| HLA-B | major histocompatibility complex, class I, B | 0.0712889 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0581632 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0581278 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0561487 |
| PTMA | prothymosin, alpha | 0.0561349 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0554805 |
| MT2A | metallothionein 2A | 0.0522064 |
| ENO1 | enolase 1, (alpha) | 0.052013 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0493619 |
| TMC5 | transmembrane channel-like 5 | 0.0486227 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0476317 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0463852 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0451743 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.0442994 |
| SMAD3 | SMAD family member 3 | 0.0436875 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0433917 |
| RNF213 | ring finger protein 213 | 0.0427596 |
| PLAT | plasminogen activator, tissue | 0.0427574 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0418186 |
| LCN2 | lipocalin 2 | 0.0415774 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0393788 |
| TGM2 | transglutaminase 2 | 0.0388517 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0386009 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0385514 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.035774 |
| EGR1 | early growth response 1 | 0.0356503 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.0356499 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0343915 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0338979 |
| RAD51B | RAD51 paralog B | 0.033872 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0337645 |
| PCDH7 | protocadherin 7 | 0.0336686 |
| ANXA4 | annexin A4 | 0.0335997 |
| CMIP | c-Maf inducing protein | 0.0331745 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0331688 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0331323 |
| KRT19 | keratin 19, type I | 0.0326626 |
| NRG3 | neuregulin 3 | 0.0326615 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0314472 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0308935 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0303167 |
| C3 | complement component 3 | 0.0303044 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0301673 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0301097 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0300208 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0299305 |
| HLA-A | major histocompatibility complex, class I, A | 0.0298253 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0295385 |
| PKM | pyruvate kinase, muscle | 0.0295174 |
| MX2 | MX dynamin-like GTPase 2 | 0.0294127 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.028121 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0279855 |
| HLA-E | major histocompatibility complex, class I, E | 0.0275709 |
| MX1 | MX dynamin-like GTPase 1 | 0.0273353 |
| PRKCA | protein kinase C, alpha | 0.0268065 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0267586 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.026526 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0261827 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.0259939 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0259472 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0258299 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0257809 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0257645 |
| ST8SIA6 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 | 0.0255708 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0255538 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.025511 |
| SP100 | SP100 nuclear antigen | 0.0246969 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0246694 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0246598 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0246572 |
| NDRG1 | N-myc downstream regulated 1 | 0.0242123 |
| VEGFA | vascular endothelial growth factor A | 0.0240758 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0240407 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0237388 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0236471 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0235822 |
| GBP4 | guanylate binding protein 4 | 0.0232199 |
| SGMS2 | sphingomyelin synthase 2 | 0.0231813 |
| PARD3 | par-3 family cell polarity regulator | 0.0231309 |
| MYO1E | myosin IE | 0.0231239 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0229331 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0223941 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0223046 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0222083 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0221398 |
| MT1E | metallothionein 1E | 0.0219939 |
| MUC1 | mucin 1, cell surface associated | 0.0218945 |
| CFB | complement factor B | 0.021893 |
| PMP22 | peripheral myelin protein 22 | 0.0218832 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0218301 |
| FAM107B | family with sequence similarity 107, member B | 0.0215921 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.112387 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0865467 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0822398 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0773588 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0717029 |
| RTN4 | reticulon 4 | -0.0711034 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0695126 |
| TMSB10 | thymosin beta 10 | -0.0678822 |
| SPAG9 | sperm associated antigen 9 | -0.0637856 |
| ASPH | aspartate beta-hydroxylase | -0.0619851 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0600616 |
| ANXA2 | annexin A2 | -0.0574685 |
| ACTG1 | actin gamma 1 | -0.0553548 |
| MAP1B | microtubule-associated protein 1B | -0.0553335 |
| LAMB3 | laminin, beta 3 | -0.0502155 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0446864 |
| VIM | vimentin | -0.043548 |
| PLAU | plasminogen activator, urokinase | -0.0432462 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0431758 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0386829 |
| RBM39 | RNA binding motif protein 39 | -0.0369848 |
| CANX | calnexin | -0.0363209 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0330879 |
| RASA2 | RAS p21 protein activator 2 | -0.0314167 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.0308515 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0307478 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0298284 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0297936 |
| OGA | O-GlcNAcase | -0.0297476 |
| TXNRD1 | thioredoxin reductase 1 | -0.0294896 |
| LAMC2 | laminin, gamma 2 | -0.0294604 |
| HMGA1 | high mobility group AT-hook 1 | -0.0293542 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0286319 |
| ABI1 | abl-interactor 1 | -0.0285381 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.028388 |
| MYO5B | myosin VB | -0.0279007 |
| NEK7 | NIMA-related kinase 7 | -0.0277172 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0275069 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0275045 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0273409 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0271789 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0271137 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0270595 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0265674 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0264005 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0262953 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0262389 |
| TOP1 | topoisomerase (DNA) I | -0.025901 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0258781 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0258037 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | -0.0252347 |
| EREG | epiregulin | -0.024946 |
| TMSB4X | thymosin beta 4, X-linked | -0.0247905 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0247899 |
| CDC73 | cell division cycle 73 | -0.0247586 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0245559 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0241461 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0236364 |
| BCL2L1 | BCL2-like 1 | -0.0234913 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0234053 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0229256 |
| USP3 | ubiquitin specific peptidase 3 | -0.0228631 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0225307 |
| PGK1 | phosphoglycerate kinase 1 | -0.0224797 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0224248 |
| ACTN4 | actinin, alpha 4 | -0.0223776 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0222664 |
| CLTC | clathrin, heavy chain (Hc) | -0.0222404 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0221816 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.0221703 |
| AREG | amphiregulin | -0.0219758 |
| IRF6 | interferon regulatory factor 6 | -0.0217767 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0217658 |
| CDK17 | cyclin-dependent kinase 17 | -0.0214855 |
| VCL | vinculin | -0.0214145 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0213833 |
| CCNL1 | cyclin L1 | -0.0213331 |
| FTL | ferritin, light polypeptide | -0.0212875 |
| FNBP1L | formin binding protein 1-like | -0.0212487 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0211685 |
| TFG | TRK-fused gene | -0.0210956 |
| POTEF | POTE ankyrin domain family, member F | -0.021076 |
| ATP11B | ATPase, class VI, type 11B | -0.0210526 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | -0.020731 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.0207005 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0205882 |
| WIPF2 | WAS/WASL interacting protein family, member 2 | -0.0204482 |
| NPTN | neuroplastin | -0.0204016 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0202577 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0198756 |
| TP53BP2 | tumor protein p53 binding protein 2 | -0.0198644 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0195198 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0194622 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0194286 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.019419 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0194128 |
| OCIAD2 | OCIA domain containing 2 | -0.0193989 |
| KIF5B | kinesin family member 5B | -0.0193454 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0190443 |
| TMEM123 | transmembrane protein 123 | -0.0187767 |
