| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil (mesylate) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belumosudil (mesylate)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.060327 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0355327 |
| FAM13A | family with sequence similarity 13, member A | 0.0338896 |
| HELZ | helicase with zinc finger | 0.0331322 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0310013 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0304827 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0292277 |
| VEGFA | vascular endothelial growth factor A | 0.0289345 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0283634 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0279875 |
| ZNF148 | zinc finger protein 148 | 0.0274683 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0263673 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0257327 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0255577 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0251982 |
| NDRG1 | N-myc downstream regulated 1 | 0.0246299 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0233792 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0227983 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0226802 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0224404 |
| GOLGA4 | golgin A4 | 0.0217265 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0216249 |
| INTS6 | integrator complex subunit 6 | 0.0214956 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0213583 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0206468 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0203472 |
| MYO1E | myosin IE | 0.0194951 |
| DNMBP | dynamin binding protein | 0.0194309 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0192556 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0191757 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0189796 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0189494 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0188055 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0186373 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0179719 |
| AP1G1 | adaptor-related protein complex 1, gamma 1 subunit | 0.0176648 |
| RPS12 | ribosomal protein S12 | 0.0175403 |
| STK38L | serine/threonine kinase 38 like | 0.017316 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0172621 |
| EGR1 | early growth response 1 | 0.017073 |
| RPS2 | ribosomal protein S2 | 0.0170659 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0170117 |
| TRPA1 | transient receptor potential cation channel, subfamily A, member 1 | 0.0169749 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0165539 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0163094 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0162977 |
| SRP54 | signal recognition particle 54kDa | 0.0162589 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0162245 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0161797 |
| RNF150 | ring finger protein 150 | 0.0161613 |
| FMN1 | formin 1 | 0.0161276 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.0160985 |
| HDGF | hepatoma-derived growth factor | 0.0160852 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0160431 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0159177 |
| RPL34 | ribosomal protein L34 | 0.0157574 |
| RPL37A | ribosomal protein L37a | 0.0153949 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.0153553 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | 0.0153473 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0152556 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0152125 |
| FERMT2 | fermitin family member 2 | 0.0150933 |
| MED13L | mediator complex subunit 13-like | 0.0150804 |
| EP300 | E1A binding protein p300 | 0.0150798 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0149863 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0148323 |
| RPL4 | ribosomal protein L4 | 0.0147928 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0146776 |
| RPS8 | ribosomal protein S8 | 0.0146534 |
| RHOA | ras homolog family member A | 0.0145837 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0144956 |
| GAPVD1 | GTPase activating protein and VPS9 domains 1 | 0.0144704 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0144391 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0143942 |
| YTHDC1 | YTH domain containing 1 | 0.0143807 |
| ZNF532 | zinc finger protein 532 | 0.0143651 |
| USP34 | ubiquitin specific peptidase 34 | 0.0141615 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0141199 |
| CXXC5 | CXXC finger protein 5 | 0.0140673 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0139565 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0137112 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0136397 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0136324 |
| CREBBP | CREB binding protein | 0.0135841 |
| SCFD1 | sec1 family domain containing 1 | 0.0135304 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0135108 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0135088 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0134395 |
| OSBP | oxysterol binding protein | 0.0134368 |
| POTEF | POTE ankyrin domain family, member F | 0.0134073 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0133832 |
| RAB30 | RAB30, member RAS oncogene family | 0.0133775 |
| MYADM | myeloid-associated differentiation marker | 0.0133716 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.013343 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0133249 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0132412 |
| NUMB | numb homolog (Drosophila) | 0.0130714 |
| EXOC4 | exocyst complex component 4 | 0.0130472 |
| RPL5 | ribosomal protein L5 | 0.0130344 |
| GDF15 | growth differentiation factor 15 | 0.0130218 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.120839 |
| LSAMP | limbic system-associated membrane protein | -0.109554 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.0827649 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0769403 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0677167 |
| EXT1 | exostosin glycosyltransferase 1 | -0.059009 |
| IGF2 | insulin-like growth factor 2 | -0.0574705 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0504568 |
| FRMD4A | FERM domain containing 4A | -0.0488489 |
| SYT1 | synaptotagmin I | -0.0470136 |
| COL3A1 | collagen, type III, alpha 1 | -0.0450641 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0447522 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0431672 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0427513 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0421787 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0416723 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0408089 |
| PLAT | plasminogen activator, tissue | -0.0406218 |
| KLHL13 | kelch-like family member 13 | -0.0406048 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0396387 |
| NREP | neuronal regeneration related protein | -0.0395889 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0384967 |
| MAP1B | microtubule-associated protein 1B | -0.0378468 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.036829 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0359861 |
| GPC5 | glypican 5 | -0.0346629 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0344972 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0344812 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0341927 |
| CADM2 | cell adhesion molecule 2 | -0.0313658 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0309261 |
| PCDH9 | protocadherin 9 | -0.0309076 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0306381 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0303299 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0297359 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0297055 |
| NBEA | neurobeachin | -0.0286516 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0286462 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0286431 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0279053 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0274524 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0262983 |
| PHF3 | PHD finger protein 3 | -0.0261405 |
| ZNF804A | zinc finger protein 804A | -0.0260437 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0257048 |
| ACTG1 | actin gamma 1 | -0.0255261 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0253728 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0252386 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0248336 |
| KCNT2 | potassium channel, sodium activated subfamily T, member 2 | -0.0241589 |
| NEK7 | NIMA-related kinase 7 | -0.0240322 |
| ANTXR1 | anthrax toxin receptor 1 | -0.023735 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0232865 |
| AEBP2 | AE binding protein 2 | -0.0229638 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0228274 |
| FOXP1 | forkhead box P1 | -0.0226841 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | -0.02238 |
| CDK12 | cyclin-dependent kinase 12 | -0.0223343 |
| TOX | thymocyte selection-associated high mobility group box | -0.0220554 |
| EDEM3 | ER degradation enhancer, mannosidase alpha-like 3 | -0.02173 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0216708 |
| LPIN1 | lipin 1 | -0.0215232 |
| RUNX1 | runt-related transcription factor 1 | -0.0214634 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0213142 |
| RNF213 | ring finger protein 213 | -0.0211729 |
| ATRNL1 | attractin-like 1 | -0.0211617 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0209536 |
| CENPF | centromere protein F, 350/400kDa | -0.0209378 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0209172 |
| MAP4 | microtubule-associated protein 4 | -0.0208265 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0205871 |
| DPH6 | diphthamine biosynthesis 6 | -0.0204801 |
| AOPEP | aminopeptidase O (putative) | -0.0204719 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0200302 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0198263 |
| FHIT | fragile histidine triad | -0.0197768 |
| CCND1 | cyclin D1 | -0.0196607 |
| STK17A | serine/threonine kinase 17a | -0.0196471 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0193292 |
| SCG2 | secretogranin II | -0.0193214 |
| COL4A6 | collagen, type IV, alpha 6 | -0.0192513 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0191968 |
| ITGA1 | integrin, alpha 1 | -0.0191215 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0191159 |
| ESRRG | estrogen-related receptor gamma | -0.0189649 |
| GLCCI1 | glucocorticoid induced 1 | -0.018937 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0188888 |
| PHF14 | PHD finger protein 14 | -0.0185691 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0184424 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0182843 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | -0.018283 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0182128 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0180936 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0179041 |
| YME1L1 | YME1-like 1 ATPase | -0.0178713 |
| ANKRD50 | ankyrin repeat domain 50 | -0.0177785 |
| RPL38 | ribosomal protein L38 | -0.0174654 |
| TNRC6B | trinucleotide repeat containing 6B | -0.017429 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0174148 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.01739 |
