| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil (mesylate) perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Belumosudil (mesylate)_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0605121 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0583682 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0518873 |
| RAD51B | RAD51 paralog B | 0.0500392 |
| TBC1D5 | TBC1 domain family, member 5 | 0.04406 |
| SMAD3 | SMAD family member 3 | 0.0437943 |
| SVIL | supervillin | 0.038098 |
| ITGB8 | integrin, beta 8 | 0.0351054 |
| SSH2 | slingshot protein phosphatase 2 | 0.0336154 |
| MACROD2 | MACRO domain containing 2 | 0.0330065 |
| SMYD3 | SET and MYND domain containing 3 | 0.0316587 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0315904 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0312454 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0312166 |
| VMP1 | vacuole membrane protein 1 | 0.0289777 |
| AXL | AXL receptor tyrosine kinase | 0.0277399 |
| PLS3 | plastin 3 | 0.0257974 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | 0.0252365 |
| ZNF148 | zinc finger protein 148 | 0.0251197 |
| PCBP2 | poly(rC) binding protein 2 | 0.0248818 |
| PRELID2 | PRELI domain containing 2 | 0.0246086 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0239538 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0236838 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0233207 |
| RPL4 | ribosomal protein L4 | 0.0228854 |
| PTK2 | protein tyrosine kinase 2 | 0.0228478 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0227848 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0226043 |
| RNF145 | ring finger protein 145 | 0.022194 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0217737 |
| SNX9 | sorting nexin 9 | 0.0217558 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0215705 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0208995 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0206145 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0206005 |
| BICC1 | BicC family RNA binding protein 1 | 0.0204229 |
| SEPTIN9 | septin 9 | 0.0203854 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0203492 |
| RPL3 | ribosomal protein L3 | 0.0202517 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0201026 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | 0.0200544 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0198552 |
| POTEF | POTE ankyrin domain family, member F | 0.0196568 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | 0.0195714 |
| PNN | pinin, desmosome associated protein | 0.0195647 |
| DIAPH1 | diaphanous-related formin 1 | 0.0194343 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0194026 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0194017 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.019265 |
| ECT2 | epithelial cell transforming 2 | 0.0191685 |
| ZNF644 | zinc finger protein 644 | 0.0188027 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0187268 |
| ANXA11 | annexin A11 | 0.0186536 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0184444 |
| ZNF638 | zinc finger protein 638 | 0.0183037 |
| ATP13A3 | ATPase type 13A3 | 0.0182803 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0182567 |
| RUNX1 | runt-related transcription factor 1 | 0.0180601 |
| TPM3 | tropomyosin 3 | 0.0179596 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0178731 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0176876 |
| PDGFC | platelet derived growth factor C | 0.0176376 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0176226 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0176106 |
| PHIP | pleckstrin homology domain interacting protein | 0.0175938 |
| PARD3 | par-3 family cell polarity regulator | 0.0172772 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0172108 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.0171491 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0171092 |
| FAM168B | family with sequence similarity 168, member B | 0.0168508 |
| KAZN | kazrin, periplakin interacting protein | 0.0166228 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0166128 |
| RPL21 | ribosomal protein L21 | 0.0165804 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0164243 |
| FOSL1 | FOS-like antigen 1 | 0.0163421 |
| TMCC1 | transmembrane and coiled-coil domain family 1 | 0.0163115 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0161813 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0161416 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0160845 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0160262 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0159683 |
| MSI2 | musashi RNA-binding protein 2 | 0.0159479 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0156743 |
| HELLS | helicase, lymphoid-specific | 0.0155987 |
| RCOR3 | REST corepressor 3 | 0.0155827 |
| AGRN | agrin | 0.0154468 |
| MATR3 | matrin 3 | 0.015403 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0153698 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0153434 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0152821 |
| NOTCH2 | notch 2 | 0.0151781 |
| CCDC50 | coiled-coil domain containing 50 | 0.0151289 |
| HELZ | helicase with zinc finger | 0.0151075 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.015066 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0150324 |
| PRRC2C | proline-rich coiled-coil 2C | 0.015015 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0150104 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0149876 |
| ZNF292 | zinc finger protein 292 | 0.0148865 |
| LMNB1 | lamin B1 | 0.0148455 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.389325 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.287207 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.165086 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.104018 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.093975 |
| TPM4 | tropomyosin 4 | -0.0932936 |
| ACTG1 | actin gamma 1 | -0.0839393 |
| LAMB3 | laminin, beta 3 | -0.0827112 |
| FTL | ferritin, light polypeptide | -0.0780795 |
| CANX | calnexin | -0.0756697 |
| ASPH | aspartate beta-hydroxylase | -0.0740534 |
| ANXA2 | annexin A2 | -0.0666931 |
| PTMA | prothymosin, alpha | -0.062201 |
| KRT7 | keratin 7, type II | -0.0619468 |
| CCND1 | cyclin D1 | -0.0616433 |
| RPS8 | ribosomal protein S8 | -0.0551477 |
| HMGA1 | high mobility group AT-hook 1 | -0.0545616 |
| AHNAK | AHNAK nucleoprotein | -0.0527235 |
| MT2A | metallothionein 2A | -0.0520912 |
| LDHA | lactate dehydrogenase A | -0.0520842 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0514512 |
| TMSB4X | thymosin beta 4, X-linked | -0.0514457 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0498776 |
| S100A10 | S100 calcium binding protein A10 | -0.0486028 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0484887 |
| CALR | calreticulin | -0.0476885 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0455704 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0454313 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0436601 |
| RPLP0 | ribosomal protein, large, P0 | -0.0419138 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0418072 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0413214 |
| TMSB10 | thymosin beta 10 | -0.040308 |
| RPL12 | ribosomal protein L12 | -0.0388865 |
| RPL35A | ribosomal protein L35a | -0.0380154 |
| RPL34 | ribosomal protein L34 | -0.0369575 |
| NDRG1 | N-myc downstream regulated 1 | -0.0368443 |
| GOLGA4 | golgin A4 | -0.0366782 |
| RACK1 | receptor for activated C kinase 1 | -0.036571 |
| IER3 | immediate early response 3 | -0.0364669 |
| SEC24D | SEC24 family member D | -0.0344251 |
| INTS6 | integrator complex subunit 6 | -0.0343867 |
| HDLBP | high density lipoprotein binding protein | -0.0338512 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0324347 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0319366 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0316285 |
| RPS24 | ribosomal protein S24 | -0.0315845 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0314484 |
| FLNB | filamin B, beta | -0.0308774 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0307972 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0306119 |
| KRT18 | keratin 18, type I | -0.0304128 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0302916 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0301694 |
| GOLGB1 | golgin B1 | -0.0301657 |
| VCAN | versican | -0.0301161 |
| RPL7A | ribosomal protein L7a | -0.0300472 |
| DSG2 | desmoglein 2 | -0.0300312 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0293598 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0292134 |
| RTN3 | reticulon 3 | -0.0290014 |
| SQSTM1 | sequestosome 1 | -0.0289473 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0287819 |
| MTDH | metadherin | -0.0285972 |
| MKI67 | marker of proliferation Ki-67 | -0.0285958 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0285778 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0283821 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0280382 |
| ARF1 | ADP-ribosylation factor 1 | -0.027186 |
| KRT19 | keratin 19, type I | -0.0270437 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0270394 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0268012 |
| CLDN1 | claudin 1 | -0.0267847 |
| UPP1 | uridine phosphorylase 1 | -0.0267825 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0267095 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0266197 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0258785 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0258037 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0255638 |
| HMGB1 | high mobility group box 1 | -0.0255457 |
| MORF4L2 | mortality factor 4 like 2 | -0.0254667 |
| RPL9 | ribosomal protein L9 | -0.0254343 |
| RPS6 | ribosomal protein S6 | -0.025312 |
| HM13 | histocompatibility (minor) 13 | -0.0250928 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0249313 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0248256 |
| SEPTIN7 | septin 7 | -0.0248067 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0245199 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0242243 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -0.0241506 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0241012 |
| SCFD1 | sec1 family domain containing 1 | -0.0238436 |
| RRBP1 | ribosome binding protein 1 | -0.0238148 |
| SRP72 | signal recognition particle 72kDa | -0.0238004 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor | -0.0237687 |
| EGFR | epidermal growth factor receptor | -0.0236391 |
| LAMC2 | laminin, gamma 2 | -0.0233499 |
| WDR45B | WD repeat domain 45B | -0.0232714 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0230648 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0227757 |
