| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil (mesylate) perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belumosudil (mesylate)_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.202973 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.188018 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.130627 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.124913 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.120519 |
| MT2A | metallothionein 2A | 0.115118 |
| CD44 | CD44 molecule (Indian blood group) | 0.0923156 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0801883 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0723267 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0721371 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0647371 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0613751 |
| UBC | ubiquitin C | 0.057715 |
| AHNAK | AHNAK nucleoprotein | 0.057506 |
| INHBA | inhibin, beta A | 0.0541236 |
| PCBP3 | poly(rC) binding protein 3 | 0.0503229 |
| MT1X | metallothionein 1X | 0.0472439 |
| ASPH | aspartate beta-hydroxylase | 0.0444467 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0433779 |
| ENO1 | enolase 1, (alpha) | 0.0428469 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0417974 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0413092 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0398755 |
| AXL | AXL receptor tyrosine kinase | 0.0386797 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0379601 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.037558 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0374451 |
| STC1 | stanniocalcin 1 | 0.0372955 |
| CLMP | CXADR-like membrane protein | 0.0364975 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0359256 |
| RPL4 | ribosomal protein L4 | 0.0357097 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0354775 |
| RNF24 | ring finger protein 24 | 0.0351552 |
| EMP1 | epithelial membrane protein 1 | 0.0348149 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0342631 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0340949 |
| SEPTIN9 | septin 9 | 0.0322841 |
| NAV1 | neuron navigator 1 | 0.032118 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.031251 |
| NAV2 | neuron navigator 2 | 0.0299127 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0297181 |
| MT1E | metallothionein 1E | 0.0294579 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0289196 |
| PDE10A | phosphodiesterase 10A | 0.0283971 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0279992 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0279725 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0278895 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0273122 |
| DUSP6 | dual specificity phosphatase 6 | 0.0267861 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0264668 |
| CCND1 | cyclin D1 | 0.0249468 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0247202 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0245676 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | 0.0244522 |
| LMNA | lamin A/C | 0.0237733 |
| YBX3 | Y box binding protein 3 | 0.0237343 |
| GPC5 | glypican 5 | 0.0236133 |
| FNIP1 | folliculin interacting protein 1 | 0.0232082 |
| RPS8 | ribosomal protein S8 | 0.0230706 |
| FAM13A | family with sequence similarity 13, member A | 0.0227359 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0226295 |
| PTMA | prothymosin, alpha | 0.0225578 |
| MLPH | melanophilin | 0.0224883 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0218577 |
| LAMB3 | laminin, beta 3 | 0.0217483 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0215077 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.021196 |
| DST | dystonin | 0.0206092 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0205704 |
| FAM107B | family with sequence similarity 107, member B | 0.0205572 |
| ANGPTL4 | angiopoietin-like 4 | 0.0201982 |
| RPL12 | ribosomal protein L12 | 0.0199694 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0198716 |
| RPLP0 | ribosomal protein, large, P0 | 0.0198127 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0197616 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0196975 |
| SDC4 | syndecan 4 | 0.019693 |
| RPL34 | ribosomal protein L34 | 0.0194398 |
| SMAD3 | SMAD family member 3 | 0.0192363 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0191916 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0189234 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0185896 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0184973 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0183271 |
| ARFGEF3 | ARFGEF family member 3 | 0.0181603 |
| G0S2 | G0/G1 switch 2 | 0.0181467 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0176177 |
| CSPP1 | centrosome and spindle pole associated protein 1 | 0.0171681 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0170374 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0169982 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0169377 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0168904 |
| CDCP1 | CUB domain containing protein 1 | 0.0168841 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0165563 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0165034 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0163568 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0163456 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0160992 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.0158098 |
| DENND5B | DENN/MADD domain containing 5B | 0.0157383 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.185269 |
| CDH13 | cadherin 13 | -0.172598 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.128313 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.121574 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.103071 |
| VCL | vinculin | -0.0967323 |
| TMSB10 | thymosin beta 10 | -0.0965506 |
| EGR1 | early growth response 1 | -0.0851229 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0577518 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0496124 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.047407 |
| COL5A1 | collagen, type V, alpha 1 | -0.0468391 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0463119 |
| RTN4 | reticulon 4 | -0.0457054 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0453398 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0450796 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0435094 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0433699 |
| RAD51B | RAD51 paralog B | -0.0418887 |
| CANX | calnexin | -0.0388524 |
| TNNC1 | troponin C type 1 (slow) | -0.0387817 |
| IGF2 | insulin-like growth factor 2 | -0.0387679 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0386493 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0384596 |
| CALD1 | caldesmon 1 | -0.0381069 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0375697 |
| PRELID2 | PRELI domain containing 2 | -0.0374505 |
| ACTG1 | actin gamma 1 | -0.0365671 |
| ACTN1 | actinin, alpha 1 | -0.0349258 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0345371 |
| RPL37A | ribosomal protein L37a | -0.0340102 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.033867 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0334236 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0331675 |
| VASP | vasodilator-stimulated phosphoprotein | -0.0321884 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0319828 |
| PLEC | plectin | -0.0314864 |
| FLNA | filamin A, alpha | -0.0310357 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0308191 |
| MCL1 | myeloid cell leukemia 1 | -0.0301677 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0297197 |
| VMP1 | vacuole membrane protein 1 | -0.0294777 |
| SPAG9 | sperm associated antigen 9 | -0.0292915 |
| RPS29 | ribosomal protein S29 | -0.0292047 |
| PGK1 | phosphoglycerate kinase 1 | -0.0285304 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0284811 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0280954 |
| RPS12 | ribosomal protein S12 | -0.0280587 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0276396 |
| ACTN4 | actinin, alpha 4 | -0.0274202 |
| POTEF | POTE ankyrin domain family, member F | -0.0271316 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0270484 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0268338 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0258363 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | -0.0257004 |
| CLIC4 | chloride intracellular channel 4 | -0.0256209 |
| TPM4 | tropomyosin 4 | -0.0255566 |
| MSN | moesin | -0.0251592 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0251367 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0250937 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0249799 |
| TPM1 | tropomyosin 1 (alpha) | -0.0246461 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0242796 |
| NABP1 | nucleic acid binding protein 1 | -0.0239703 |
| TUBB6 | tubulin, beta 6 class V | -0.0237125 |
| FTL | ferritin, light polypeptide | -0.0236452 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0236167 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0234815 |
| DIAPH2 | diaphanous-related formin 2 | -0.023423 |
| RBM39 | RNA binding motif protein 39 | -0.0232353 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0228855 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | -0.0227934 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0227524 |
| RPL38 | ribosomal protein L38 | -0.0221993 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0221251 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0220153 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0219833 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0219628 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0218503 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0218182 |
| RPLP2 | ribosomal protein, large, P2 | -0.0215816 |
| FMN1 | formin 1 | -0.0209538 |
| HDLBP | high density lipoprotein binding protein | -0.0205253 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | -0.0205044 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0204412 |
| USP22 | ubiquitin specific peptidase 22 | -0.0200767 |
| LDHA | lactate dehydrogenase A | -0.0199997 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0197917 |
| WDR1 | WD repeat domain 1 | -0.0197579 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0196981 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0195807 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0194252 |
| PLS3 | plastin 3 | -0.0193199 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0193029 |
| CLTC | clathrin, heavy chain (Hc) | -0.0192894 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0189831 |
| ARF4 | ADP-ribosylation factor 4 | -0.0188616 |
| RPS3 | ribosomal protein S3 | -0.0188323 |
| OGA | O-GlcNAcase | -0.0186103 |
| RASA3 | RAS p21 protein activator 3 | -0.0183289 |
