| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil (mesylate) perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Belumosudil (mesylate)_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EXT1 | exostosin glycosyltransferase 1 | 0.119846 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0759741 |
| RPLP1 | ribosomal protein, large, P1 | 0.0750565 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.065861 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0642023 |
| LMO7 | LIM domain 7 | 0.0617492 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0573158 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0517419 |
| SMAD3 | SMAD family member 3 | 0.0505098 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0490359 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0474341 |
| FBXO32 | F-box protein 32 | 0.0470892 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0467044 |
| FTL | ferritin, light polypeptide | 0.0437095 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0433137 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0426439 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0407138 |
| EXPH5 | exophilin 5 | 0.0391947 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0380361 |
| SGMS2 | sphingomyelin synthase 2 | 0.0346016 |
| EMP1 | epithelial membrane protein 1 | 0.0340907 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0337637 |
| RPL34 | ribosomal protein L34 | 0.0334148 |
| TLE4 | transducin-like enhancer of split 4 | 0.0327183 |
| RPL35A | ribosomal protein L35a | 0.0326376 |
| S100A10 | S100 calcium binding protein A10 | 0.0323594 |
| MYO1E | myosin IE | 0.0321434 |
| RPS2 | ribosomal protein S2 | 0.0320223 |
| RND3 | Rho family GTPase 3 | 0.0314033 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0301349 |
| RPS4X | ribosomal protein S4, X-linked | 0.0298278 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0282376 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0273838 |
| VCL | vinculin | 0.0271323 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0270055 |
| HMGB1 | high mobility group box 1 | 0.026492 |
| FOXO1 | forkhead box O1 | 0.0263933 |
| SIK3 | SIK family kinase 3 | 0.0262898 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | 0.0259202 |
| RPL21 | ribosomal protein L21 | 0.0257336 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0255219 |
| RPL23 | ribosomal protein L23 | 0.0255168 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.025124 |
| RPLP0 | ribosomal protein, large, P0 | 0.0248645 |
| YBX1 | Y box binding protein 1 | 0.0248553 |
| RPS19 | ribosomal protein S19 | 0.024838 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.024808 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0241801 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0240732 |
| RPL4 | ribosomal protein L4 | 0.0235526 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0232611 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | 0.0230426 |
| CCNYL1 | cyclin Y-like 1 | 0.0229991 |
| ATP5F1E | ATP synthase F1 subunit epsilon | 0.0229045 |
| FOXO3 | forkhead box O3 | 0.0228016 |
| SHROOM3 | shroom family member 3 | 0.0227425 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0226197 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0213793 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.0213392 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0213074 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0212251 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0211708 |
| H1-0 | H1.0 linker histone | 0.0210688 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0210468 |
| MYOF | myoferlin | 0.0206739 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0205546 |
| SLMAP | sarcolemma associated protein | 0.0200215 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0197516 |
| RASEF | RAS and EF-hand domain containing | 0.0194817 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0192894 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0190715 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0189958 |
| RPL39 | ribosomal protein L39 | 0.0187077 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0183461 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0180631 |
| RPL12 | ribosomal protein L12 | 0.017631 |
| HBP1 | HMG-box transcription factor 1 | 0.0175733 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0175271 |
| NT5DC3 | 5'-nucleotidase domain containing 3 | 0.0174536 |
| ATF3 | activating transcription factor 3 | 0.0173601 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.0173237 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.017191 |
| IRS2 | insulin receptor substrate 2 | 0.0170637 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0169904 |
| EFNB2 | ephrin-B2 | 0.0168494 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0165921 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0165744 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0162319 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0161412 |
| GNAS | GNAS complex locus | 0.01582 |
| HMGN2 | high mobility group nucleosomal binding domain 2 | 0.0156433 |
| PLK2 | polo-like kinase 2 | 0.0155579 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0155184 |
| CRY1 | cryptochrome circadian clock 1 | 0.0154495 |
| ADM | adrenomedullin | 0.0153078 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.0152789 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0151677 |
| RPL7 | ribosomal protein L7 | 0.0149312 |
| INTS6 | integrator complex subunit 6 | 0.0149107 |
| KRT20 | keratin 20, type I | 0.0148305 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | -0.0924387 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0918185 |
| NDRG1 | N-myc downstream regulated 1 | -0.0872238 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0811637 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0784205 |
| ANXA2 | annexin A2 | -0.0780133 |
| WASF2 | WAS protein family, member 2 | -0.0719167 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0706009 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0704605 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0688862 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0684431 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.0661916 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0650867 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0648918 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0633841 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0614905 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0610085 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0572612 |
| LDHA | lactate dehydrogenase A | -0.0572365 |
| ACTN4 | actinin, alpha 4 | -0.0564298 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0558342 |
| PGK1 | phosphoglycerate kinase 1 | -0.0552663 |
| NF1 | neurofibromin 1 | -0.0543549 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0541935 |
| PTK2 | protein tyrosine kinase 2 | -0.0540161 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.052607 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0507176 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.050142 |
| FRY | furry homolog (Drosophila) | -0.0495819 |
| DST | dystonin | -0.0490811 |
| DGKH | diacylglycerol kinase, eta | -0.0480529 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0474862 |
| DIAPH2 | diaphanous-related formin 2 | -0.0473707 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0462563 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0462311 |
| CANX | calnexin | -0.0459214 |
| ASPH | aspartate beta-hydroxylase | -0.0434768 |
| STK24 | serine/threonine kinase 24 | -0.043325 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0431507 |
| AGR2 | anterior gradient 2 | -0.0430752 |
| JUP | junction plakoglobin | -0.0427382 |
| ITGA6 | integrin, alpha 6 | -0.0422533 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0418413 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0418279 |
| RNF213 | ring finger protein 213 | -0.0414805 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0413151 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0397186 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.039718 |
| HDLBP | high density lipoprotein binding protein | -0.0397122 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.039653 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0392187 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0385443 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0383563 |
| HM13 | histocompatibility (minor) 13 | -0.0381409 |
| LYZ | lysozyme | -0.0378545 |
| ACTG1 | actin gamma 1 | -0.0365005 |
| EXOC4 | exocyst complex component 4 | -0.0364744 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0364623 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0363337 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0361434 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.036024 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0358679 |
| CD2AP | CD2-associated protein | -0.0357422 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0355974 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0355302 |
| TPM4 | tropomyosin 4 | -0.0349046 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0344466 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0338295 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0337797 |
| ATXN1 | ataxin 1 | -0.0335678 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0333998 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0329777 |
| EGR1 | early growth response 1 | -0.0329424 |
| MUC13 | mucin 13, cell surface associated | -0.0327929 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0327394 |
| TMEM123 | transmembrane protein 123 | -0.0326922 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0326163 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0325891 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0324483 |
| RRBP1 | ribosome binding protein 1 | -0.031862 |
| UGT1A6 | UDP glucuronosyltransferase 1 family, polypeptide A6 | -0.0317905 |
| FNBP4 | formin binding protein 4 | -0.0315237 |
| TMSB10 | thymosin beta 10 | -0.0313385 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0310495 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0306571 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0306344 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0303329 |
| PYGB | phosphorylase, glycogen; brain | -0.0301918 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0300696 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0300251 |
| HYOU1 | hypoxia up-regulated 1 | -0.0299751 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | -0.0299433 |
| RPS3 | ribosomal protein S3 | -0.0299145 |
| GOLGB1 | golgin B1 | -0.0296208 |
| COG5 | component of oligomeric golgi complex 5 | -0.0293304 |
| KLF12 | Kruppel-like factor 12 | -0.0292035 |
| THOC2 | THO complex 2 | -0.0284278 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0283726 |
| BPTF | bromodomain PHD finger transcription factor | -0.0283294 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0280691 |
