| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil (mesylate) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Belumosudil (mesylate)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.171651 |
| LMO7 | LIM domain 7 | 0.138236 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.101044 |
| RPS8 | ribosomal protein S8 | 0.097185 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.08943 |
| RAI14 | retinoic acid induced 14 | 0.0882313 |
| MTSS1 | metastasis suppressor 1 | 0.0874031 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0848512 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.084751 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0825438 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0794002 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.076299 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0721059 |
| CD44 | CD44 molecule (Indian blood group) | 0.0682074 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0681175 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0645756 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0638751 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0630873 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | 0.0608322 |
| UBC | ubiquitin C | 0.0594879 |
| H1-0 | H1.0 linker histone | 0.0593375 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0591092 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0536903 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0533245 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0526107 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0513265 |
| RPS6 | ribosomal protein S6 | 0.0484158 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0478146 |
| RPL4 | ribosomal protein L4 | 0.0474254 |
| HLA-E | major histocompatibility complex, class I, E | 0.0467519 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0456399 |
| AHNAK | AHNAK nucleoprotein | 0.04506 |
| CALB1 | calbindin 1, 28kDa | 0.0448013 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0446417 |
| RPS3 | ribosomal protein S3 | 0.0430832 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0425904 |
| RASAL2 | RAS protein activator like 2 | 0.0412684 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0411512 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.03986 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0391843 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0391093 |
| INTS6 | integrator complex subunit 6 | 0.0379264 |
| ANXA1 | annexin A1 | 0.0377579 |
| SQSTM1 | sequestosome 1 | 0.0376051 |
| CNTNAP3 | contactin associated protein-like 3 | 0.0374945 |
| SULF2 | sulfatase 2 | 0.0359582 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0357775 |
| DOK5 | docking protein 5 | 0.0357586 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0356843 |
| RPL13A | ribosomal protein L13a | 0.0353086 |
| DUSP6 | dual specificity phosphatase 6 | 0.03482 |
| NAV2 | neuron navigator 2 | 0.0335817 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0335645 |
| JMJD1C | jumonji domain containing 1C | 0.0330164 |
| RNF217 | ring finger protein 217 | 0.0315503 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0307501 |
| RPS12 | ribosomal protein S12 | 0.029977 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0294453 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0286622 |
| HMGA2 | high mobility group AT-hook 2 | 0.0284176 |
| MT1E | metallothionein 1E | 0.0281973 |
| RPS25 | ribosomal protein S25 | 0.0279069 |
| FAM107B | family with sequence similarity 107, member B | 0.0278049 |
| RPL37 | ribosomal protein L37 | 0.0272072 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0269776 |
| HDAC9 | histone deacetylase 9 | 0.0269168 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.0266178 |
| RND3 | Rho family GTPase 3 | 0.0264847 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0263581 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0259253 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0256924 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0250007 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0246823 |
| RPL12 | ribosomal protein L12 | 0.0244896 |
| PRSS23 | protease, serine, 23 | 0.0243312 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0240969 |
| PTK2 | protein tyrosine kinase 2 | 0.0237231 |
| RPL8 | ribosomal protein L8 | 0.0232715 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0232468 |
| MEGF6 | multiple EGF-like-domains 6 | 0.0232467 |
| EMP1 | epithelial membrane protein 1 | 0.0228968 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0226488 |
| HSPA1A | heat shock 70kDa protein 1A | 0.022622 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0226089 |
| RPL21 | ribosomal protein L21 | 0.0222962 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | 0.0222781 |
| RACK1 | receptor for activated C kinase 1 | 0.0221164 |
| CSTB | cystatin B (stefin B) | 0.0221137 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0217093 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0214761 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0214568 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0211138 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.021069 |
| RPLP0 | ribosomal protein, large, P0 | 0.0208529 |
| PDGFB | platelet-derived growth factor beta polypeptide | 0.0204145 |
| RPS23 | ribosomal protein S23 | 0.0202301 |
| RPL31 | ribosomal protein L31 | 0.020226 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0201528 |
| IFI44L | interferon-induced protein 44-like | 0.0201029 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0200321 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | -0.173186 |
| NDRG1 | N-myc downstream regulated 1 | -0.136213 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.119459 |
| BCL2L1 | BCL2-like 1 | -0.0962735 |
| POTEF | POTE ankyrin domain family, member F | -0.0941101 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0828805 |
| CUL4B | cullin 4B | -0.0821938 |
| ITGA6 | integrin, alpha 6 | -0.0791185 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0790264 |
| SULF1 | sulfatase 1 | -0.0666459 |
| ANLN | anillin, actin binding protein | -0.0653581 |
| PLAT | plasminogen activator, tissue | -0.0650737 |
| RBM39 | RNA binding motif protein 39 | -0.0639491 |
| KRT17 | keratin 17, type I | -0.0551781 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0543156 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0542122 |
| RIN2 | Ras and Rab interactor 2 | -0.0532525 |
| MSN | moesin | -0.0526912 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0518579 |
| ASPH | aspartate beta-hydroxylase | -0.0515394 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -0.050725 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0506017 |
| MYOF | myoferlin | -0.0493679 |
| TMSB10 | thymosin beta 10 | -0.0470847 |
| PGK1 | phosphoglycerate kinase 1 | -0.0468925 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.046035 |
| FOXO1 | forkhead box O1 | -0.0454626 |
| EFHD2 | EF-hand domain family, member D2 | -0.0447172 |
| CANX | calnexin | -0.0441338 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0429773 |
| SERINC3 | serine incorporator 3 | -0.0427585 |
| OGA | O-GlcNAcase | -0.0423099 |
| PLEC | plectin | -0.0418735 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0413659 |
| TPX2 | TPX2, microtubule-associated | -0.0402182 |
| MCL1 | myeloid cell leukemia 1 | -0.0400137 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0398908 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.0394235 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | -0.0389434 |
| SMAD3 | SMAD family member 3 | -0.0387714 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | -0.0379294 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0376788 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0373072 |
| NEK7 | NIMA-related kinase 7 | -0.0370278 |
| SPAG9 | sperm associated antigen 9 | -0.0368897 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0364018 |
| ARRDC3 | arrestin domain containing 3 | -0.0355134 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.03471 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0341799 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.033855 |
| RPS21 | ribosomal protein S21 | -0.0337699 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0332915 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0332018 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0330417 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0327903 |
| TPM4 | tropomyosin 4 | -0.0327766 |
| FN1 | fibronectin 1 | -0.0327152 |
| LNPEP | leucyl/cystinyl aminopeptidase | -0.0326055 |
| PDLIM1 | PDZ and LIM domain 1 | -0.0325965 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0324667 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.032197 |
| IGF2 | insulin-like growth factor 2 | -0.0320266 |
| CLINT1 | clathrin interactor 1 | -0.0320257 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0319488 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0316152 |
| RPS2 | ribosomal protein S2 | -0.0315091 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0312927 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -0.0312486 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0312165 |
| EZR | ezrin | -0.031063 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0306627 |
| PODXL | podocalyxin-like | -0.0305517 |
| EPHA2 | EPH receptor A2 | -0.0299008 |
| CAPRIN2 | caprin family member 2 | -0.0296885 |
| LMNA | lamin A/C | -0.0296877 |
| BLCAP | bladder cancer associated protein | -0.0296077 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0292902 |
| PRELID2 | PRELI domain containing 2 | -0.0287144 |
| METTL15 | methyltransferase like 15 | -0.0285619 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0280386 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0280084 |
| MATR3 | matrin 3 | -0.0279402 |
| NUP58 | nucleoporin 58 | -0.0279031 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0278939 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0278725 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0278463 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0278259 |
| FAR1 | fatty acyl CoA reductase 1 | -0.0276656 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | -0.0276305 |
| PKM | pyruvate kinase, muscle | -0.0274617 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0273162 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.027262 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | -0.0271613 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0271262 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0271246 |
| XPO1 | exportin 1 | -0.0270679 |
| TNS4 | tensin 4 | -0.0270577 |
| TXNRD1 | thioredoxin reductase 1 | -0.0269797 |
| FOSL1 | FOS-like antigen 1 | -0.0268096 |
| NRG1 | neuregulin 1 | -0.0267443 |
