| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Belumosudil (mesylate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Belumosudil (mesylate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0985018 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0903865 |
| INTS6 | integrator complex subunit 6 | 0.0750257 |
| TLE4 | transducin-like enhancer of split 4 | 0.0676442 |
| VCL | vinculin | 0.0599291 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0588133 |
| ENO1 | enolase 1, (alpha) | 0.0586685 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.05351 |
| TENM3 | teneurin transmembrane protein 3 | 0.0501849 |
| DST | dystonin | 0.0491205 |
| ATXN1 | ataxin 1 | 0.0447142 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0424134 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0411482 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0408595 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0407194 |
| ASPH | aspartate beta-hydroxylase | 0.0397373 |
| PLSCR1 | phospholipid scramblase 1 | 0.0393232 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0387996 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0385358 |
| ERBIN | erbb2 interacting protein | 0.0374245 |
| PHACTR1 | phosphatase and actin regulator 1 | 0.0360416 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0359457 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0358673 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0356213 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0352149 |
| RIGI | RNA sensor RIG-I | 0.0346849 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.034521 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.034465 |
| SMAD3 | SMAD family member 3 | 0.0340552 |
| CALD1 | caldesmon 1 | 0.0338817 |
| PRELID2 | PRELI domain containing 2 | 0.0323541 |
| NAV2 | neuron navigator 2 | 0.0309911 |
| RAD51B | RAD51 paralog B | 0.0299811 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0299612 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0298875 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0284071 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0283971 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.028057 |
| COL5A1 | collagen, type V, alpha 1 | 0.0278369 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0275854 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.0265394 |
| FNIP1 | folliculin interacting protein 1 | 0.0257335 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0255326 |
| DNAH11 | dynein, axonemal, heavy chain 11 | 0.0255245 |
| FHIT | fragile histidine triad | 0.0248445 |
| AEBP2 | AE binding protein 2 | 0.0246299 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0246287 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.0242343 |
| RNF213 | ring finger protein 213 | 0.0237162 |
| SEPTIN9 | septin 9 | 0.023694 |
| RPL4 | ribosomal protein L4 | 0.0234475 |
| TNS3 | tensin 3 | 0.0230477 |
| SQSTM1 | sequestosome 1 | 0.0228925 |
| SP100 | SP100 nuclear antigen | 0.0228818 |
| IFI44L | interferon-induced protein 44-like | 0.0228393 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.022424 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | 0.0223293 |
| EPC2 | enhancer of polycomb homolog 2 (Drosophila) | 0.0221916 |
| HDAC9 | histone deacetylase 9 | 0.0219319 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | 0.0217322 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0216212 |
| MYO1E | myosin IE | 0.0214954 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0213171 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0212849 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0210133 |
| KLF12 | Kruppel-like factor 12 | 0.0208689 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0208673 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0208624 |
| PRKCA | protein kinase C, alpha | 0.0208292 |
| FLNA | filamin A, alpha | 0.0206789 |
| UBC | ubiquitin C | 0.0206461 |
| TUFT1 | tuftelin 1 | 0.0205507 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0203195 |
| EXOC4 | exocyst complex component 4 | 0.0201322 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0199993 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0199365 |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) | 0.0199162 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0197787 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0194898 |
| CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.0194436 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0193738 |
| TPM3 | tropomyosin 3 | 0.0193038 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0192155 |
| NABP1 | nucleic acid binding protein 1 | 0.0192098 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0188618 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.01876 |
| MX1 | MX dynamin-like GTPase 1 | 0.0186075 |
| SLC12A8 | solute carrier family 12, member 8 | 0.0182057 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0181079 |
| RBBP6 | retinoblastoma binding protein 6 | 0.0181033 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0180341 |
| FAM219A | family with sequence similarity 219, member A | 0.0179741 |
| IPO9 | importin 9 | 0.0179216 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0179107 |
| NRXN3 | neurexin 3 | 0.0179079 |
| CUX1 | cut-like homeobox 1 | 0.0178417 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0178057 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.0177413 |
| ZNF804A | zinc finger protein 804A | 0.0176697 |
| FBXO32 | F-box protein 32 | 0.0176628 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.20594 |
| FTL | ferritin, light polypeptide | -0.169747 |
| MT2A | metallothionein 2A | -0.160093 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.155272 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.136184 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.132434 |
| HLA-B | major histocompatibility complex, class I, B | -0.112548 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0983603 |
| ATP13A3 | ATPase type 13A3 | -0.0755568 |
| MT1X | metallothionein 1X | -0.0725547 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0693634 |
| CD44 | CD44 molecule (Indian blood group) | -0.0644539 |
| DEK | DEK proto-oncogene | -0.064266 |
| PTMA | prothymosin, alpha | -0.0641756 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0604198 |
| RPL35A | ribosomal protein L35a | -0.0602681 |
| ADM | adrenomedullin | -0.0589862 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.058401 |
| TXNRD1 | thioredoxin reductase 1 | -0.0520695 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0519895 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0501048 |
| GOLGA4 | golgin A4 | -0.0486376 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0486011 |
| TMSB4X | thymosin beta 4, X-linked | -0.0478913 |
| TMSB10 | thymosin beta 10 | -0.0470084 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0466861 |
| CALR | calreticulin | -0.0464173 |
| VIM | vimentin | -0.0440001 |
| ARF4 | ADP-ribosylation factor 4 | -0.0437421 |
| ANXA2 | annexin A2 | -0.0426354 |
| JUN | jun proto-oncogene | -0.042571 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0423279 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0419554 |
| B2M | beta-2-microglobulin | -0.0411492 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0402782 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0401009 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0399155 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0394456 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0394442 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0392356 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0389488 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0385038 |
| TUBB | tubulin, beta class I | -0.0384832 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0383037 |
| NUP58 | nucleoporin 58 | -0.0380471 |
| S100A6 | S100 calcium binding protein A6 | -0.0376194 |
| FOSL1 | FOS-like antigen 1 | -0.0375634 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0375316 |
| NOP58 | NOP58 ribonucleoprotein | -0.0370275 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0363187 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0351634 |
| PGK1 | phosphoglycerate kinase 1 | -0.0346664 |
| TPD52 | tumor protein D52 | -0.0340883 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0339348 |
| PFN1 | profilin 1 | -0.0338677 |
| RLF | rearranged L-myc fusion | -0.0333515 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0332811 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0328053 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | -0.0327532 |
| USP3 | ubiquitin specific peptidase 3 | -0.0323174 |
| RBM39 | RNA binding motif protein 39 | -0.0321772 |
| HMGB1 | high mobility group box 1 | -0.0318543 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0315058 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0312134 |
| PPME1 | protein phosphatase methylesterase 1 | -0.030982 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0309606 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0309489 |
| FAR1 | fatty acyl CoA reductase 1 | -0.0308598 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0307281 |
| RPLP2 | ribosomal protein, large, P2 | -0.0303606 |
| S100A10 | S100 calcium binding protein A10 | -0.0297453 |
| RPL12 | ribosomal protein L12 | -0.0293712 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.029331 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0292054 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0289297 |
| POSTN | periostin, osteoblast specific factor | -0.0287575 |
| TFG | TRK-fused gene | -0.0287212 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0281917 |
| MPZL1 | myelin protein zero-like 1 | -0.0280713 |
| CANX | calnexin | -0.0278724 |
| NDRG1 | N-myc downstream regulated 1 | -0.0274159 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -0.027383 |
| MORF4L2 | mortality factor 4 like 2 | -0.0272721 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0271793 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0270123 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0269375 |
| RBM25 | RNA binding motif protein 25 | -0.0269374 |
| AFAP1 | actin filament associated protein 1 | -0.0269261 |
| SEPTIN7 | septin 7 | -0.0267398 |
| IER3 | immediate early response 3 | -0.0266721 |
| YBX1 | Y box binding protein 1 | -0.0264654 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0264312 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0262353 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0261523 |
| GOLT1B | golgi transport 1B | -0.026149 |
| RAI1 | retinoic acid induced 1 | -0.0259024 |
| RPL35 | ribosomal protein L35 | -0.0258451 |
| SRP54 | signal recognition particle 54kDa | -0.0257686 |
| HMGB2 | high mobility group box 2 | -0.0257364 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0257184 |
